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Home > Archive > Kidney Failure > February 2006 > *High* Protein/Input Please
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*High* Protein/Input Please
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| Just came from my first consultation with the nephrologist. I was referred
to him because My 24 hour urine protein was 2850. Diabetic diagnosed for
appx 2 years but BG was rarely over 200. and is well controlled. As for
neuropathy--I had carpal tunnel release in right hand and need the left
done. Also have chronic spotty numbness in both feet. Water retention,
edema. I was always thin but have gained the past several years since
difficult-to-control hypothyroid--am now taking 275 mcg synthroid daily.
That's a lot! The most overweight I've been is 20/25 pounds. HGBA1C was 5.9
in July and creat. was .9 I now have to have more bloodwork scheduled as
well as ultrasound then biopsy if no explanation found for the high protein.
I am 53 with 2 elementary school age sons, so I'd like to stick around for a
while ;-) . How uncommon is it to have protein level this high with no
evidence of kidney failure? Are there any nutrients that might help? I feel
exhausted most of the time. Thanks much!
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| Pierre 2006-02-25, 9:56 pm |
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"Gini" <gini@verizon.com> wrote in message
news:VlhAf.193$Jn1.152@trndny01...
How uncommon is it to have protein level this high with no
> evidence of kidney failure? Are there any nutrients that might help? I
> feel exhausted most of the time. Thanks much!
>
It's not uncommon at all. Proteinuria can be heavy even if you still have
normal kidney function (for now, anyway, as proteinuria definitely is a risk
factor for progression to chronic renal insufficiency). But the level of
proteinuria itself is not directly related to kidney function, and it also
doesn't necessarily increase as kidney function is lost. Better get that
under control though!
Pierre
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| In article <VlhAf.193$Jn1.152@trndny01>, "Gini" <gini@verizon.com>
wrote:
> Just came from my first consultation with the nephrologist. I was referred
> to him because My 24 hour urine protein was 2850. Diabetic diagnosed for
> appx 2 years but BG was rarely over 200. and is well controlled. As for
> neuropathy--I had carpal tunnel release in right hand and need the left
> done. Also have chronic spotty numbness in both feet. Water retention,
> edema. I was always thin but have gained the past several years since
> difficult-to-control hypothyroid--am now taking 275 mcg synthroid daily.
> That's a lot! The most overweight I've been is 20/25 pounds. HGBA1C was 5.9
> in July and creat. was .9 I now have to have more bloodwork scheduled as
> well as ultrasound then biopsy if no explanation found for the high protein.
> I am 53 with 2 elementary school age sons, so I'd like to stick around for a
> while ;-) . How uncommon is it to have protein level this high with no
> evidence of kidney failure? Are there any nutrients that might help? I feel
> exhausted most of the time. Thanks much!
You probably have diabetic nephropathy, but only a biopsy will confirm
that. That is a kidney disease common in diabetics (chances are that you
were diabetic years before you were diagnosed, unless it was brought on
by steroids). You have near-nephrotic-level proteinuria, which would be
3000 mg/24 hours (3 gms). It is possible to have benign proteinuria, but
at that rate, it is not terribly likely; it is more likely that there is
some underlying disease. That does not mean that your kidneys are
failing, or if they are, you are probably in the very early stages of
failure, and some 20+ years away from dialysis.
There are no dietary measures you can take; however, it may be a good
idea to stop taking ALL NSAIDs (ibuprofen, Aleve, Toradol, etc) as they
all increase proteinuria. Your doctor may put you on either ACE
inhibitors or ARBs; both are are antihypertensives routinely given to
even normotensive diabetics to delay or retard the progress of kidney
disease, and they both can slow proteinuria (ARBs ar usually prescribed
if one cannot tolerate the side-effects of ACE inhibitors).
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
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"Pierre" <nospamemail@anonymous.com> wrote in message
news:xaiAf.22267$xk1.609745@news20.bellglobal.com...
>
> "Gini" <gini@verizon.com> wrote in message
> news:VlhAf.193$Jn1.152@trndny01...
> How uncommon is it to have protein level this high with no
>
> It's not uncommon at all. Proteinuria can be heavy even if you still have
> normal kidney function (for now, anyway, as proteinuria definitely is a
> risk factor for progression to chronic renal insufficiency). But the level
> of proteinuria itself is not directly related to kidney function, and it
> also doesn't necessarily increase as kidney function is lost. Better get
> that under control though!
===
Thanks Pierre! You have provided encouragement. I had wondered whether the
proteinuria
can be transient. My urine became darker about a year ago but lately it has
been normal color.
===
===
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"REP" <rep@inanna.com> wrote
"Gini" wrote:
>
...............................[vbcol=seagreen]
> You probably have diabetic nephropathy, but only a biopsy will confirm
> that. That is a kidney disease common in diabetics (chances are that you
> were diabetic years before you were diagnosed, unless it was brought on
> by steroids). You have near-nephrotic-level proteinuria, which would be
> 3000 mg/24 hours (3 gms). It is possible to have benign proteinuria, but
> at that rate, it is not terribly likely; it is more likely that there is
> some underlying disease. That does not mean that your kidneys are
> failing, or if they are, you are probably in the very early stages of
> failure, and some 20+ years away from dialysis.
===
Thanks REP. No steroids. The nephrologist said I could have had undetected
diabetes
but I did have a baby in 1995 and I'm presuming since so much blood/urine is
taken when pregnant, they whould have detected high BG and protein. So,
my best guess is that diabetes and proteinuria began at some point in the
last
10 years, although I've been to he doc frequently while trying to get my
hypothroid
and BP under control. My GP has told me to not take nsaids at all. I did
take a lot
of ibuprofen for migraines since my 30s but quit taking it after I was put
on atenolol for migraine
prevention 10 years ago. I haven't had a migraine since. I was put on
accupril
about two years ago when diabetes was diagnosed. Thanks again for your
input. It has been very
helpful.
===
===
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| Pierre 2006-02-25, 9:56 pm |
| Hi Gini
Just so there's no misunderstanding, the kind of proteinuria you get from
having diabetes is not really transient. The *high level* of proteinuria may
be transient in that it can be managed down to a more reasonable level with
the right medication. But as I said in my previous post, it is something
that MUST be followed-up. By the time you have any proteinuria, which is
defined as more than 150mg per day, and if it is being caused by the
kidneys, then you already have kidney damage which must be dealt with. In a
person with diabetes, chances are it's diabetic nephropathy (but it could be
other types of nephropathy too).
Pierre
"Gini" <gini@verizon.com> wrote in message news:hGpAf.244$Jn1.77@trndny01...
>
> Thanks Pierre! You have provided encouragement. I had wondered whether the
> proteinuria
> can be transient. My urine became darker about a year ago but lately it
> has been normal color.
> ===
> ===
>
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"Pierre" <nospamemail@anonymous.com> wrote in message
news:kprAf.22461$xk1.642364@news20.bellglobal.com...
> Hi Gini
>
> Just so there's no misunderstanding, the kind of proteinuria you get from
> having diabetes is not really transient. The *high level* of proteinuria
> may be transient in that it can be managed down to a more reasonable level
> with the right medication. But as I said in my previous post, it is
> something that MUST be followed-up. By the time you have any proteinuria,
> which is defined as more than 150mg per day, and if it is being caused by
> the kidneys, then you already have kidney damage which must be dealt with.
> In a person with diabetes, chances are it's diabetic nephropathy (but it
> could be other types of nephropathy too).
===
Thank you, Pierre. Understood. I know I am in for a lot of doctor
appointments!
(Fortunately, we have good insurance.)
===
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| In article <kprAf.22461$xk1.642364@news20.bellglobal.com>,
"Pierre" <nospamemail@anonymous.com> wrote:
> Hi Gini
>
> Just so there's no misunderstanding, the kind of proteinuria you get from
> having diabetes is not really transient. The *high level* of proteinuria may
> be transient in that it can be managed down to a more reasonable level with
> the right medication. But as I said in my previous post, it is something
> that MUST be followed-up. By the time you have any proteinuria, which is
> defined as more than 150mg per day, and if it is being caused by the
> kidneys, then you already have kidney damage which must be dealt with. In a
> person with diabetes, chances are it's diabetic nephropathy (but it could be
> other types of nephropathy too).
Or glomerulosclerosis! Then again, I had proteinuria for years before I
became diabetic (I have FSGS, confirmed by biopsy).
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
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