| plz.spam.here@gmail.com 2006-10-17, 4:28 pm |
| This is the drug that Ortho Biotech licensed from Curis in late 2002.
Unfortunately there is no evidence that Ortho has done anything with
BMP-7 since then. Is this because it is puts their current blockbuster
drug Procit/Epoetin (http://www.orthobiotech.com/procrit.html) at risk?
I really hope not, but who knows?
BMP-7 and the Kidney, Introduction:
Several recent studies have demonstrated unequivocally that
administration of bone morphogenic protein-7 (BMP-7) has a therapeutic
effect in various animal models of acute and chronic renal injury
(Table 1). However, the underlying mechanisms of BMP-7 action in the
kidney remained largely unknown in these initial reports. Here, novel
aspects regarding the biology of BMP-7 in the kidney will be discussed.
Full study: http://ndt.oxfordjournals.org/cgi/content/full/21/3/568
Ortho licensing BMP-7 from Curis:
http://curis.com/product_detail.php?id=3
How can we get Ortho to actually do something with BMP-7, besides
sitting on it?
P.
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