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Home > Archive > Kidney Failure > March 2005 > curious about two drugs for kidney failure?
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curious about two drugs for kidney failure?
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| Sensipar and Procrit ?
Does anyone have any experience with either of these two meds ?
Thanks,
Rick
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| Lizz Parsons 2005-03-19, 6:25 pm |
| Procrit is used to increase red blood cell production to help
anemia... not a specific kidney med.
It was actually developed for chemo patients, and you'll see
commercials for it from time to time.
Not sure about sensipar.
~Lizz
Kidney Recipient: 8/23/04
UCSF
On Tue, 8 Mar 2005 18:53:31 -0600, "rick" <gorwell1984@comcast.net>
wrote:
>Sensipar and Procrit ?
>
>Does anyone have any experience with either of these two meds ?
>
>Thanks,
>Rick
>
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| In article <b9Kdne2SDecf1LPfRVn-hg@comcast.com>,
"rick" <gorwell1984@comcast.net> wrote:
> Sensipar and Procrit ?
>
> Does anyone have any experience with either of these two meds ?
Procrit is used to treat anemia (and from the labs you posted, you're
not anemic). Sensipar is used for patients on dialysis with
hyperparathyrodism caused by the dialysis. These drugs do not treat
kidney disease, but complications of kidney disease/failure.
The drugs used to treat/slow the progress of kidney disease are: ACE
inhibitors, ARBs (both ACE inhibitors and ARBs are hypotensive agents
that have protective properties on the kidneys, even in the absence of
high blood pressure), corticosteroids and fish oil (for certain kidney
diseases). Some diseases, like FSGS, show almost no response to any
treatment, but ACE inhibitors or ARBs are tried anyway, while others,
like diabetic nephropathy, repsond well to ACE inhibitor/ARB therapy.
IgA Nephropathy repsonds well to fish oil, but most other kidney
diseases show no change.
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
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| "(and from the labs you posted, you're
not anemic)."
REP,
Even though my red blood cell count is 4.16 , hemoglobin 12.5 and hematocrit
36.8 ? Those indicies (numbers) don't necessarily relate to anemia ?
How low would the above numbers need to be before I would be considered
anemic?
Thanks,
Rick
"REP" <rep@inanna.com> wrote in message
news:397a81F5o0kbpU1@individual.net...
> In article <b9Kdne2SDecf1LPfRVn-hg@comcast.com>,
> "rick" <gorwell1984@comcast.net> wrote:
>
>
> Procrit is used to treat anemia (and from the labs you posted, you're
> not anemic). Sensipar is used for patients on dialysis with
> hyperparathyrodism caused by the dialysis. These drugs do not treat
> kidney disease, but complications of kidney disease/failure.
>
> The drugs used to treat/slow the progress of kidney disease are: ACE
> inhibitors, ARBs (both ACE inhibitors and ARBs are hypotensive agents
> that have protective properties on the kidneys, even in the absence of
> high blood pressure), corticosteroids and fish oil (for certain kidney
> diseases). Some diseases, like FSGS, show almost no response to any
> treatment, but ACE inhibitors or ARBs are tried anyway, while others,
> like diabetic nephropathy, repsond well to ACE inhibitor/ARB therapy.
> IgA Nephropathy repsonds well to fish oil, but most other kidney
> diseases show no change.
>
> --
> "Did Father shoot him? I will eat Grandfather for dinner."
> - Helen Keller, on learning of the death of her grandfather
| |
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| In article <BcqdnR-yeOv567PfRVn-uA@comcast.com>,
"rick" <gorwell1984@comcast.net> wrote:
> "(and from the labs you posted, you're
> not anemic)."
>
> REP,
> Even though my red blood cell count is 4.16 , hemoglobin 12.5 and hematocrit
> 36.8 ? Those indicies (numbers) don't necessarily relate to anemia ?
Normal range RBC 3.6-5.1; yours is 4.16 or NORMAL. Normal range
homoglobin is 11.5-15.0; yours is 12.5 or NORMAL. Normal hematocrit is
34.0-46.0; yours is 36.8 or NORMAL.
So no, you're not anemic. You're a long, long way from anemic. Your
kidneys are fine, too - at least from the numbers you gave, and assuming
the slightly elevated BUN is from your enlarged prostate. Worry about
keeping your diabetes under control, and not this stuff.
> How low would the above numbers need to be before I would be considered
> anemic?
Let your doctor tell you.
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
| |
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| I don't know why the "normal" reference ranges vary from lab to lab. Per my
GP, they take the patient's age, gender, medical history, family history,
etc into consideration when figuring the reference ranges. My doctor
explained this much to me several years ago. My wife goes to the same doctor
and her CBC goes to the same exact lab that mine does. But her reference
ranges are different than with mine on many things, I.E. RBC, hemoglobin,
just to name a few. Plus her glucose even is 110 max on her reference range
where mine is 120. That's because of my diabetes (per my doctor).
Anyway, all of the numbers I gave above were abnormal acording to (both) the
lab and my doctor?
Rick
"REP" <rep@inanna.com> wrote in message
news:397cdkF55i02aU1@individual.net...
> In article <BcqdnR-yeOv567PfRVn-uA@comcast.com>,
> "rick" <gorwell1984@comcast.net> wrote:
>
>
> Normal range RBC 3.6-5.1; yours is 4.16 or NORMAL. Normal range
> homoglobin is 11.5-15.0; yours is 12.5 or NORMAL. Normal hematocrit is
> 34.0-46.0; yours is 36.8 or NORMAL.
>
> So no, you're not anemic. You're a long, long way from anemic. Your
> kidneys are fine, too - at least from the numbers you gave, and assuming
> the slightly elevated BUN is from your enlarged prostate. Worry about
> keeping your diabetes under control, and not this stuff.
>
>
> Let your doctor tell you.
>
> --
> "Did Father shoot him? I will eat Grandfather for dinner."
> - Helen Keller, on learning of the death of her grandfather
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| Then you need another doctor who knows what they are doing because the lab
ranges quoted here are what every doctor I've seen has gone by for the last
12 years. Believe me if your hematocrit were below normal you would feel
it. You'd be lucky to drag your XXX out of bed each day and be able to stay
awake. I can only wish for an 11.5. I haven't been able to get at or above
10.2 in over 2 months and I've been using procrit for 6 months now.
Celeste
"rick" <gorwell1984@comcast.net> wrote in message
news:BcqdnR-yeOv567PfRVn-uA@comcast.com...
> "(and from the labs you posted, you're
> not anemic)."
>
> REP,
> Even though my red blood cell count is 4.16 , hemoglobin 12.5 and
hematocrit
> 36.8 ? Those indicies (numbers) don't necessarily relate to anemia ?
>
> How low would the above numbers need to be before I would be considered
> anemic?
>
> Thanks,
> Rick
>
> "REP" <rep@inanna.com> wrote in message
> news:397a81F5o0kbpU1@individual.net...
>
>
| |
|
| In article <YIMXd.101163$QS5.41378@trndny06>,
"Spot" <NoSpamMe@verizon.net> wrote:
> Then you need another doctor who knows what they are doing because the lab
> ranges quoted here are what every doctor I've seen has gone by for the last
> 12 years. Believe me if your hematocrit were below normal you would feel
> it. You'd be lucky to drag your XXX out of bed each day and be able to stay
> awake. I can only wish for an 11.5. I haven't been able to get at or above
> 10.2 in over 2 months and I've been using procrit for 6 months now.
Per another post from the OP, he also suffers from hypochondria, a real
disorder. The reference ranges from the lab used for this panel may show
he is very slightly out of range, but with a history of poorly
controlled diabetes and enlarged prostate, I'm guessing that there's no
mystery to these results and most certainly no anemia or kidney failure
(or at least no failure so severe as to require Procrit or Sensipar).
Unfortunately for the OP, the best to forestall future kidney problems
is through the tedious work of tight glucose control, and not throwing
handfuls of expensive pills down his throat.
> "rick" <gorwell1984@comcast.net> wrote in message
> news:BcqdnR-yeOv567PfRVn-uA@comcast.com...
> hematocrit
>
>
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
| |
| Richard Archer 2005-03-19, 6:25 pm |
|
"Spot" <NoSpamMe@verizon.net> wrote in message
news:YIMXd.101163$QS5.41378@trndny06...
> Then you need another doctor who knows what they are doing because the lab
> ranges quoted here are what every doctor I've seen has gone by for the
> last
> 12 years. Believe me if your hematocrit were below normal you would feel
> it. You'd be lucky to drag your XXX out of bed each day and be able to
> stay
> awake. I can only wish for an 11.5. I haven't been able to get at or
> above
> 10.2 in over 2 months and I've been using procrit for 6 months now.
>
> Celeste
>
Celeste
I was in a similar position to you a few months back (hb floating around
10) - although I take Aranesp not Procrit.
My doctor first tried increasing the Aranesp dosage, but this failed to have
any effect, then they tried me on Iron infusions (10mg per month - done
whilst on dialysis) this seems to have worked, I'm now bouncing around with
a hb of 11.5-12.0.
It seems that if your Iron stores are low, all the EPO in the world won't
get your hb up.
regards
Richard Archer
> "rick" <gorwell1984@comcast.net> wrote in message
> news:BcqdnR-yeOv567PfRVn-uA@comcast.com...
> hematocrit
>
>
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| Richard,
Thanks for the information but my iron stores are perfectly fine. I am not
lacking in the iron I wish that were the case.........
My problem is the lisinopril that they had to put me on to slow down the
deterioration of transplanted kidney. It has the bad side effect of
repressing hematocrit production. It has slowed down the deteoration of my
transplant from loosing a whopping 21% function in 6 months time down to
about 3% per 6 months. I'll tell you I was scared there for a while until
this stuff stabilized. I was looking at the fact of probably being back on
dialysis by now if it hadn't been for the med changes slowing this down.
It's sucks being whiped out about 2 days out of 7 but if it means that I can
squeeze more time out of this kidney before it gives up I'll put up with it.
I just had to make the adjustment of taking my shot from Wednesday to a
Monday that way by the time I'm whiped out it's on the weekend and it
doesn't affect my work any.
I've always been a person who's hard to get a steady hematocrit on even when
I was on dialysis and doing infed iron my levels would still yo yo around.
Thanks
Celeste ~ going on 8+ years and shooting for a lot more.
"Richard Archer" <mrrichardarcher@nospam.com> wrote in message
news:d0rn4f$fhs$1@newsg4.svr.pol.co.uk...
>
> "Spot" <NoSpamMe@verizon.net> wrote in message
> news:YIMXd.101163$QS5.41378@trndny06...
lab[vbcol=seagreen]
feel[vbcol=seagreen]
> Celeste
>
> I was in a similar position to you a few months back (hb floating around
> 10) - although I take Aranesp not Procrit.
> My doctor first tried increasing the Aranesp dosage, but this failed to
have
> any effect, then they tried me on Iron infusions (10mg per month - done
> whilst on dialysis) this seems to have worked, I'm now bouncing around
with
> a hb of 11.5-12.0.
> It seems that if your Iron stores are low, all the EPO in the world won't
> get your hb up.
>
> regards
>
> Richard Archer
>
of[vbcol=seagreen]
kidney[vbcol=seagreen]
>
>
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