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Home > Archive > Kidney Failure > March 2005 > Ace Inhibitors can signifcantly delay Kidney Disease (ESRD)
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Ace Inhibitors can signifcantly delay Kidney Disease (ESRD)
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| Billy the Kid ney 2005-03-19, 6:25 pm |
| Hello,
I'm sending this as general information as I think it may help some of
you out there.
In several centers doctors are now prescribing a small dosage of Ace
inhibitors (a blood pressure drug) in order to delay the onset of ESRD
in children. Studies on mice with Alport's Syndrome show a
"significant"
prolonging of kidney function when treatment is started early.
Apparently, scaring from proteinuria is dramatically reduced. My
kids take just one small pill a day (2.5mg) and the insurance company
pays. The treatment should benefit many types of kidney diseases.
My center, in Cologne, Germany (Merheim Medical Center), is one of the
top centers for Alport Syndrome. They believe the treatment can delay
ESRD in children by 10 to 15 years!! This is especially important in
Alport Syndrome boys, who usually progress to ESRD by about age 20.
For girls the benefits are expected to last a lifetime!! In addition,
some centers are now prescribing Omega Fish Oil and Vitamin E for
additional protection. Unfortunately, I do not know of any sites in
other countries working with this treatment. But, most doctors should
already know about it.
Additionally, my doctors have prescribed it to me in order to help
protect my transplanted kidney of 18 years.
STUDY: "Pre-emptive Ramipril Therapy Delays Renal Failure and Reduces
Renal Fibrosis in ... Mice with Alport Syndrome", Dr. Oliver Gross,
Cologne Merheim Medical Center
LINK:
www.alport.de/english/Paper%20Ramipril.pdf
Regards,
Bill in Germany
Kidney Transplant, Ohio State University, 1987.
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| In article <e4db8a47.0502180320.2703cf77@posting.google.com>,
ski-1967@t-email.de (Billy the Kid ney) wrote:
> Hello,
>
> I'm sending this as general information as I think it may help some of
> you out there.
>
> In several centers doctors are now prescribing a small dosage of Ace
> inhibitors (a blood pressure drug) in order to delay the onset of ESRD
> in children.
It's standard in the US for diabetics to be put on ACE inhibitors or
ARBs to protect the kidneys, as well as those with proteinuria over 1
g/day and other adults at risk of developing significant kidney disease.
At least, it's the standard recommendation; many in the US have trouble
affording even 'cheap' drugs like ACE inhibitors.
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
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| Homefinders 2005-03-19, 6:25 pm |
| Hi Billy,
You said, "Additionally, my doctors have prescribed it to me in order to
help protect my transplanted kidney of 18 years".
Unfortunately, you didn't say what "it" is. Is it the Ace inhibitor, the
Vitamin E or the Omega Fish Oil? They were all mentioned in the same
paragraph.
Judanne
"Billy the Kid ney" <ski-1967@t-email.de> wrote in message
news:e4db8a47.0502180320.2703cf77@posting.google.com...
> Hello,
>
> I'm sending this as general information as I think it may help some of
> you out there.
>
> In several centers doctors are now prescribing a small dosage of Ace
> inhibitors (a blood pressure drug) in order to delay the onset of ESRD
> in children. Studies on mice with Alport's Syndrome show a
> "significant"
> prolonging of kidney function when treatment is started early.
> Apparently, scaring from proteinuria is dramatically reduced. My
> kids take just one small pill a day (2.5mg) and the insurance company
> pays. The treatment should benefit many types of kidney diseases.
>
> My center, in Cologne, Germany (Merheim Medical Center), is one of the
> top centers for Alport Syndrome. They believe the treatment can delay
> ESRD in children by 10 to 15 years!! This is especially important in
> Alport Syndrome boys, who usually progress to ESRD by about age 20.
> For girls the benefits are expected to last a lifetime!! In addition,
> some centers are now prescribing Omega Fish Oil and Vitamin E for
> additional protection. Unfortunately, I do not know of any sites in
> other countries working with this treatment. But, most doctors should
> already know about it.
>
> Additionally, my doctors have prescribed it to me in order to help
> protect my transplanted kidney of 18 years.
>
> STUDY: "Pre-emptive Ramipril Therapy Delays Renal Failure and Reduces
> Renal Fibrosis in ... Mice with Alport Syndrome", Dr. Oliver Gross,
> Cologne Merheim Medical Center
>
> LINK:
> www.alport.de/english/Paper%20Ramipril.pdf
>
> Regards,
> Bill in Germany
> Kidney Transplant, Ohio State University, 1987.
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| Billy the Kid ney 2005-03-19, 6:25 pm |
| Hi Judanne,
Sorry about the misunderstanding.
I am referring to the Ace Inhibitors as "it" below. My doctors have
prescribed Ace inhititors. Regarding the omega fish oil and vitamin
E, I cannot get a prescriptions for these in Germany, but as my docs
recommend them I buy them myself. Fish Oil (I take about 500 to 1000
mg/day) is cheap at big discounters (e.g. Costcos). Vitamin E I get
from a good multivitamin taken most days (I think my multivitamin
contains about 400IU).
Fish Oil helps blood pressure and also protects the heart.
Regarding the cost: I see it as an investment; but I admit that I may
not take the fish oil and multivitamins every day in order to save
some costs or I just forget.
Regards,
Bill in Germany
Kidney Transplant, Ohio State University, 1987.
_________________
"Homefinders" <judanne@bigpond.net.au> wrote in message news:<inURd.167971$K7.84219@news-server.bigpond.net.au>...
> Hi Billy,
>
> You said, "Additionally, my doctors have prescribed it to me in order to
> help protect my transplanted kidney of 18 years".
>
> Unfortunately, you didn't say what "it" is. Is it the Ace inhibitor, the
> Vitamin E or the Omega Fish Oil? They were all mentioned in the same
> paragraph.
| |
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| "many in the US have trouble
affording even 'cheap' drugs like ACE inhibitors".
You can buy the generic Zestril from online pharmacies for 44 cents per
pill!!! (lisinopril).
I've bought them from internet pharmacies for less than my co-pay insurance
charges me (insurance copay is $15. per month).
Same exact meds I get from Walmart pharmacy.
"REP" <rep@inanna.com> wrote in message
news:37m5jkF5frcuhU1@individual.net...
> In article <e4db8a47.0502180320.2703cf77@posting.google.com>,
> ski-1967@t-email.de (Billy the Kid ney) wrote:
>
>
> It's standard in the US for diabetics to be put on ACE inhibitors or
> ARBs to protect the kidneys, as well as those with proteinuria over 1
> g/day and other adults at risk of developing significant kidney disease.
> At least, it's the standard recommendation; many in the US have trouble
> affording even 'cheap' drugs like ACE inhibitors.
>
> --
> "Did Father shoot him? I will eat Grandfather for dinner."
> - Helen Keller, on learning of the death of her grandfather
| |
|
| In article <Nc2dnefnWYsa7rPfRVn-qg@comcast.com>,
"rick" <gorwell1984@comcast.net> wrote:
> "many in the US have trouble
> affording even 'cheap' drugs like ACE inhibitors".
>
> You can buy the generic Zestril from online pharmacies for 44 cents per
> pill!!! (lisinopril).
>
> I've bought them from internet pharmacies for less than my co-pay insurance
> charges me (insurance copay is $15. per month).
> Same exact meds I get from Walmart pharmacy.
Not everyone has medical insurance or insurance that covers
prescriptions. For older diabetics - a group at highest risk for renal
failure - on Medicare/Medicaid and Social Security, even an extra $15 a
month can be a big bite out of their budgets.
--
"Did Father shoot him? I will eat Grandfather for dinner."
- Helen Keller, on learning of the death of her grandfather
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