Home > Archive > Lasik Eyes Surgery > August 2006 > Acanthamoeba keratitis after LASIK. Her eyes are ruined, may need corneal transplant!





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Author Acanthamoeba keratitis after LASIK. Her eyes are ruined, may need corneal transplant!
Ace

2006-08-25, 8:27 am

PURPOSE: To report a case of Acanthamoeba infection following LASIK.
METHODS: A 20-year-old woman developed pain, redness, decreased vision,
and corneal infiltrate in the right eye 15 days after bilateral LASIK.
She did not use contact lenses postoperatively. Patient examination 3
months after surgery revealed a large, central, full-thickness corneal
infiltrate with multiple satellite lesions in the right eye. Corneal
scrapings were taken and the flap excised, and submitted for
histopathologic examination. RESULTS: Microscopic examination of smears
revealed Acanthamoeba cysts and non-nutrient agar showed a significant
growth of Acanthamoeba. Histopathology examination of the excised flap
demonstrated numerous Acanthamoeba cysts in tissue sections. The
infiltrate was treated with a combination of topical polyhexamethylene
biguanide, chlorhexidine, atropine sulfate, and oral itraconazole and
resolved within 2 months. CONCLUSIONS: Laser in situ keratomileusis can
be complicated by Acanthamoeba infection. Microbiologic evaluation is
essential for accurate early diagnosis and treatment.

Ace

2006-08-30, 9:33 pm


Ace wrote:
> PURPOSE: To report a case of Acanthamoeba infection following LASIK.
> METHODS: A 20-year-old woman developed pain, redness, decreased vision,
> and corneal infiltrate in the right eye 15 days after bilateral LASIK.
> She did not use contact lenses postoperatively. Patient examination 3
> months after surgery revealed a large, central, full-thickness corneal
> infiltrate with multiple satellite lesions in the right eye. Corneal
> scrapings were taken and the flap excised, and submitted for
> histopathologic examination. RESULTS: Microscopic examination of smears
> revealed Acanthamoeba cysts and non-nutrient agar showed a significant
> growth of Acanthamoeba. Histopathology examination of the excised flap
> demonstrated numerous Acanthamoeba cysts in tissue sections. The
> infiltrate was treated with a combination of topical polyhexamethylene
> biguanide, chlorhexidine, atropine sulfate, and oral itraconazole and
> resolved within 2 months. CONCLUSIONS: Laser in situ keratomileusis can
> be complicated by Acanthamoeba infection. Microbiologic evaluation is
> essential for accurate early diagnosis and treatment.




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