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Home > Archive > Lasik Eyes Surgery > May 2005 > LASIK patients! Read about your sick corneas!
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LASIK patients! Read about your sick corneas!
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| Cornea
Volume 24(1) January 2005 pp 92-102
Pathologic Findings in Postmortem Corneas After Successful Laser In Situ
Keratomileusis
Kramer, Theresa R MD, MBA; Chuckpaiwong, Varintorn MD; Dawson, Daniel G MD;
L'Hernault, Nancy; Grossniklaus, Hans E MD; Edelhauser, Henry F PHD
From the Emory Eye Center, Emory University, Atlanta, GA.
Received for publication February 23, 2004
Excerpts from text:
Pathologic Findings
Gross examination of the corneas was notable for hazy areas of scarring at
the wound margin of the LASIK flap in 95% of corneas.
On light microscopy, the corneal stroma in or adjacent to the lamellar wound
was marked by several pathologic changes including eosinophilic deposits,
PAS-positive
extracellular matrix material, and varying numbers and types of keratocytes,
while on TEM, electron-dense granular material, activated keratocytes, and
quiescent keratocytes with small (0.25-2 [mu]m diameter) intracytoplasmic
vacuoles were detected in the same regions. Eosinophilic deposits were found
in the wound in 43 of 43 corneas, and PAS-positive material was found in the
wound in 43 of 43 corneas (Fig. 3A and B). On TEM, deposits of
electron-dense granular material interspersed with randomly ordered collagen
fibrils were seen in the
lamellar wound and adjacent to keratocytes (Fig. 4A,B). Activated
keratocytes (ie, prominent rough endoplasmic reticulum, mitochondria, golgi,
and electron dense material filled vesicles) were present in or adjacent to
the wound in 4 of 33 corneas (Fig. 5A). Vacuolated keratocytes with small
variably sized vacuoles were present in or adjacent to the wound in 32 of 33
corneas. The abundance and size of the vacuolations in the keratocytes
correlated slightly
with the length of postoperative period, with grading levels 2 and 3 being
more common in the early postoperative period. Additionally, in all cases in
which electron-dense granular material was particularly abundant, an
activated or a quiescent keratocyte was located in the immediate area.
Intracytoplasmic stress fiber bundles in keratocytes suggestive of
myofibroblast differentiation were identified in only one cornea at the
wound margin. Further immunohistochemical analysis is underway to positively
identify and locate keratocytes with myofibroblastic differentiation. In one
cornea, extracellular vacuoles were identified in the stroma .
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| serebel 2005-05-01, 5:57 pm |
| In other words, the cornea has been altered so people can see again.
This is truly evil.
SErebel
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| ycdbsoya 2005-05-02, 11:51 am |
| So, the RS was a success, but the patient died?
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| Glenn - USAEyes.org 2005-05-02, 5:53 pm |
| With or without refractive surgery, you are not going to get out of
life alive.
Glenn Hagele
Executive Director
Council for Refractive Surgery Quality Assurance
Email to glenn dot hagele at usaeyes dot org
http://www.USAEyes.org
http://www.ComplicatedEyes.org
I am not a doctor.
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| Richard 2005-05-02, 5:53 pm |
| Glenn - USAEyes.org <glenn.hageleSTOPSPAM@USAEyes.org> wrote in
news:1k3d71duqqdcbvl3c344m4prmb3cdsia7r@4ax.com:
> With or without refractive surgery, you are not going to get out of
> life alive.
>
Damnit, there you go dashing my hopes.
--
Richard
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| Glenn - USAEyes.org 2005-05-02, 10:54 pm |
| Yea, I've been known to do that now and again.
8^)
Glenn Hagele
Executive Director
Council for Refractive Surgery Quality Assurance
Email to glenn dot hagele at usaeyes dot org
http://www.USAEyes.org
http://www.ComplicatedEyes.org
I am not a doctor.
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| serebel 2005-05-02, 10:54 pm |
| For a piece of garbage like Frank Boydston, yup it was a success, was
yours ?
SErebel
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| LASIKtruth 2005-05-07, 10:52 pm |
| No, the cornea has been trashed by doctors who know this is happening and
keep this information from patients, denying them informed consent. Anybody
who really understood LASIK would not want it for their own eyes. This is
why Glenn didn't have is CRSQA surgeons perform LASIK on him. Glenn will
never have LASIK because he knows it's too risky and reduces overall visual
quality.
"serebel" <serebel@aol.com> wrote in message
news:1114920558.536650.211590@o13g2000cwo.googlegroups.com...
> In other words, the cornea has been altered so people can see again.
> This is truly evil.
>
> SErebel
>
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| serebel 2005-05-07, 10:52 pm |
| Now how would you convince the millions of happy post lasik people?
SErebel
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