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Author MUSe and other questions. (Need advice from you guys!)
stryped

2006-09-05, 4:23 pm

x-no-archive:yes

Hi all.
I don't know if you remember me, but I have had problems with PE. I
sometimes have minor problems with erection but with help (from wife) I
am always able to have intercourse. (Although sometimes erection leaves
a lot to be desired).

I am 35 and seem to be in good physical health. I run 4 miles 3 or more
days a week. I watch what I eat. I am 6 feet tall and about 177 lbs.

Abyway, I have been wanting to try something that may allow me to have
an erection after ejaculation due to the PE and something that would
help get a firmer erection. About 2 years ago I took I think 50 mg.
Viagra and also a Paxil pill. I read a study that this could
significantly length the amount of time you last. Well, I took it on an
empty stomach. About 20 minutes later I ate supper and drank a beer. My
wife said my lips looked red. Suddenly my face was red and on fire. So
bad I had to sit in front of a fan. Also, my heart started beating
about 100 bpm. I thought I was going to die. It went away before bed
though.

A day or so later I started having periods where I felt like I had to
make myself breath. I also had periods for several months after that in
the evening where I would feel that something was not right, I would
get sick at my stomach and dizzy and felt like something was just not
right. I went to two cardiologists. I had a normal stress test, normal
ekg (twice) normal echocardiogram, I wore an even monitor for a month
and also a 24 hour monitor. Everything was normal expect for periods
of SVT's and short runs of tachycardia. (Which I am not sure but I
think were there even before the Viagra).

I have not had any of those episodes for over a year.

To make a long story short, I wrote a letter to my family doctor asking
about MUSE. To my surprise they called me and asked me where I send the
prescription. Has anyone had any bad reactions to it? I am thinking
about taking the first dose at my local hospital on the weekend just to
see what reaction if any I could have. I have read it can lower blood
pressure but in very few people. (In trials, I think 3% of 1500
people.) I have been checking my blood pressure with a wrist cuff at
work and it has been: 105/55, 108/55, 100/70, 119/67, 114/57. My
resting pulse averages from 42-57. (I guess because I exercise.) Most
people I hear from have no effects from it other than the pain and
buring. That would be ok I think, I just don't want it to do anything
else. I have been checked out the last two years by family doctors and
cardiologist, had blood work, etc. No problems.
But I don't want to get back to where I was after the Viagra. I
thought something was wrong with me and I was going to die.

What do you guys think? Also, can I keep MUSe in my freezer in the
garage? My wife does not want me on medication for my PE even though we
talked about it. So, I would rather not tell her about it until I see
how it works. (With her of course!)

Also, I know many of you would say, go see a urologist. But my
insurance will not pay for anything "sexually related" I went to a
urologist for this last year and he was less then helpful and I had to
pay the entire bill.

LMac

2006-09-05, 4:23 pm

OK, one more time. I think that there's enough discussion so that you
can make up your own mind on this one. It's your choice to make.

First, review the posts on the PE & MUSE thread that ran from 8/15/06
thru 8/21/06 -- cull the good info from those posts. My reading of that
thread showed a consensus that it would be difficult to absorb enough
Alprostadil into one's bloodstream to trigger hypotension. However,
that consensus is a majority view and few of the members of this group
have the extreme reaction to vasodialators that you describe.

I assume that your "3%" figure came from the clinical trials data:

< http://www.drugs.com/pdr/muse_urethral_suppository.html >

(Specifically in the Precautions and Warnings section.)

My own advice: Since you have had rather extreme reactions to other
vasodialators, you probably fall into that 3%. The smartmoney says to
avoid MUSE.

One more factor: Using this med without your spouse's knowledge will
probably add psychological stress to any pharmacological response.

Forget MUSE.

....Lmac


stryped wrote:
> x-no-archive:yes
>
> Hi all.
> I don't know if you remember me, but I have had problems with PE. I
> sometimes have minor problems with erection but with help (from wife) I
> am always able to have intercourse. (Although sometimes erection leaves
> a lot to be desired).
>
> I am 35 and seem to be in good physical health. I run 4 miles 3 or more
> days a week. I watch what I eat. I am 6 feet tall and about 177 lbs.
>
> Abyway, I have been wanting to try something that may allow me to have
> an erection after ejaculation due to the PE and something that would
> help get a firmer erection. About 2 years ago I took I think 50 mg.
> Viagra and also a Paxil pill. I read a study that this could
> significantly length the amount of time you last. Well, I took it on an
> empty stomach. About 20 minutes later I ate supper and drank a beer. My
> wife said my lips looked red. Suddenly my face was red and on fire. So
> bad I had to sit in front of a fan. Also, my heart started beating
> about 100 bpm. I thought I was going to die. It went away before bed
> though.
>
> A day or so later I started having periods where I felt like I had to
> make myself breath. I also had periods for several months after that in
> the evening where I would feel that something was not right, I would
> get sick at my stomach and dizzy and felt like something was just not
> right. I went to two cardiologists. I had a normal stress test, normal
> ekg (twice) normal echocardiogram, I wore an even monitor for a month
> and also a 24 hour monitor. Everything was normal expect for periods
> of SVT's and short runs of tachycardia. (Which I am not sure but I
> think were there even before the Viagra).
>
> I have not had any of those episodes for over a year.
>
> To make a long story short, I wrote a letter to my family doctor asking
> about MUSE. To my surprise they called me and asked me where I send the
> prescription. Has anyone had any bad reactions to it? I am thinking
> about taking the first dose at my local hospital on the weekend just to
> see what reaction if any I could have. I have read it can lower blood
> pressure but in very few people. (In trials, I think 3% of 1500
> people.) I have been checking my blood pressure with a wrist cuff at
> work and it has been: 105/55, 108/55, 100/70, 119/67, 114/57. My
> resting pulse averages from 42-57. (I guess because I exercise.) Most
> people I hear from have no effects from it other than the pain and
> buring. That would be ok I think, I just don't want it to do anything
> else. I have been checked out the last two years by family doctors and
> cardiologist, had blood work, etc. No problems.
> But I don't want to get back to where I was after the Viagra. I
> thought something was wrong with me and I was going to die.
>
> What do you guys think? Also, can I keep MUSe in my freezer in the
> garage? My wife does not want me on medication for my PE even though we
> talked about it. So, I would rather not tell her about it until I see
> how it works. (With her of course!)
>
> Also, I know many of you would say, go see a urologist. But my
> insurance will not pay for anything "sexually related" I went to a
> urologist for this last year and he was less then helpful and I had to
> pay the entire bill.
>

stryped

2006-09-05, 4:23 pm


LMac wrote:[vbcol=seagreen]
> OK, one more time. I think that there's enough discussion so that you
> can make up your own mind on this one. It's your choice to make.
>
> First, review the posts on the PE & MUSE thread that ran from 8/15/06
> thru 8/21/06 -- cull the good info from those posts. My reading of that
> thread showed a consensus that it would be difficult to absorb enough
> Alprostadil into one's bloodstream to trigger hypotension. However,
> that consensus is a majority view and few of the members of this group
> have the extreme reaction to vasodialators that you describe.
>
> I assume that your "3%" figure came from the clinical trials data:
>
> < http://www.drugs.com/pdr/muse_urethral_suppository.html >
>
> (Specifically in the Precautions and Warnings section.)
>
> My own advice: Since you have had rather extreme reactions to other
> vasodialators, you probably fall into that 3%. The smartmoney says to
> avoid MUSE.
>
> One more factor: Using this med without your spouse's knowledge will
> probably add psychological stress to any pharmacological response.
>
> Forget MUSE.
>
> ...Lmac
>
>
> stryped wrote:

I guess I was thinking that since MUSE works differently that it would
not have the side effects. Yes, I did get the 3% from the drug website.
I also wonder if some of the after effects of the Viagra were
pshychological. (Although the inital reaction after taking it was not).

So, basically there is no hope then if you say I cant take any
vasodialators?

Wanderer

2006-09-05, 4:23 pm

On Tue, 5 Sep 2006 11:59:41 -0400, stryped wrote
(in article <1157471981.705274.196240@e3g2000cwe.googlegroups.com> ):

>
> LMac wrote:
>
> I guess I was thinking that since MUSE works differently that it would
> not have the side effects. Yes, I did get the 3% from the drug website.
> I also wonder if some of the after effects of the Viagra were
> pshychological. (Although the inital reaction after taking it was not).
>
> So, basically there is no hope then if you say I cant take any
> vasodialators?
>


A lot of people get flushing from Viagra, especially at higher doses. 50 mg
is a relatively high dose for someone who doesn't have significant erection
problems. 25 mg or less would probably achieve the same effect without the
extreme flushing. Based on other posts of yours I have read, I think you
should at least consider the fact that might be a hypochondriac. The
after-symptoms that you ascribe to Viagra seem like they might be a
psychological reaction rather than a physical one. A lot of the issues you
have raised in various emails -- baffling symptoms, asking people to pray for
your recovery from ailments that turn out to be imaginary, premature
ejaculation, difficulties being open with your wife, strange reactions to
drugs, erection problems that come and go, etc. -- suggest to me that you
might benefit from some form of psychological counseling. It's possible that
you have some form of inner conflict/guilt regarding sexuality that needs to
be resolved. I hope this opinion doesn't offend you. Like LMac, I doubt that
Muse will prove to be a long-term solution for you. But I doubt you will do
yourself serious harm by trying it out.

Wanderer

stryped

2006-09-05, 4:23 pm

x-no-archive:yes

None of my problems were "imagineary" and I do believe in the power of
prayer. What difficulties have I had about being open with my wife? She
knows the PE is a problem and I have told her that I was reserving the
right to get treatment with or without her.

I just called and the doctor apparently calle din the highest dose for
MUSE, 1000mcg. I am a little afraid to try that much. SHould I ask for
125 or 250 do you think?
Wanderer wrote:
> On Tue, 5 Sep 2006 11:59:41 -0400, stryped wrote
> (in article <1157471981.705274.196240@e3g2000cwe.googlegroups.com> ):
>
>
> A lot of people get flushing from Viagra, especially at higher doses. 50 mg
> is a relatively high dose for someone who doesn't have significant erection
> problems. 25 mg or less would probably achieve the same effect without the
> extreme flushing. Based on other posts of yours I have read, I think you
> should at least consider the fact that might be a hypochondriac. The
> after-symptoms that you ascribe to Viagra seem like they might be a
> psychological reaction rather than a physical one. A lot of the issues you
> have raised in various emails -- baffling symptoms, asking people to pray for
> your recovery from ailments that turn out to be imaginary, premature
> ejaculation, difficulties being open with your wife, strange reactions to
> drugs, erection problems that come and go, etc. -- suggest to me that you
> might benefit from some form of psychological counseling. It's possible that
> you have some form of inner conflict/guilt regarding sexuality that needs to
> be resolved. I hope this opinion doesn't offend you. Like LMac, I doubt that
> Muse will prove to be a long-term solution for you. But I doubt you will do
> yourself serious harm by trying it out.
>
> Wanderer


Muerta

2006-09-06, 4:23 pm


"stryped" <stryped@hotmail.com> wrote in message
news:1157488891.614655.188290@d34g2000cwd.googlegroups.com...
> x-no-archive:yes
>
> What difficulties have I had about being open with my >wife?


Uh, she doesn't want you on meds, so you decide you need meds and choose not
to tell her?

Hmmmm....I got sexual problems...my wife doesn't want me to treat
them........???


Jim

2006-09-06, 4:23 pm


stryped wrote:
> x-no-archive:yes
>
> None of my problems were "imagineary" and I do believe in the power of
> prayer. What difficulties have I had about being open with my wife? She
> knows the PE is a problem and I have told her that I was reserving the
> right to get treatment with or without her.
>
> I just called and the doctor apparently calle din the highest dose for
> MUSE, 1000mcg. I am a little afraid to try that much. SHould I ask for
> 125 or 250 do you think?

_____

According to everything I've heard from my urologists and everything I
have read here and elsewhere, MUSE is probably the least effective ED
drug out there, as well as the one which is most likely to cause penile
pain.

My suggestion: Take what the doctor ordered and see what happens.

Jim

itazuke

2006-09-08, 4:22 pm

I echo Jim's comments; MUSE is the least effective stimulant etc. Not
only that, but if your wife "goes down" on you, she's gonna know you
used something. MUSE really tastes NASTY. Most everyone who ever
tried it, HATED it. Canadian MD's used to really push it on to their
patients. I hope that got stopped.
John
Jim wrote:
> stryped wrote:
> _____
>
> According to everything I've heard from my urologists and everything I
> have read here and elsewhere, MUSE is probably the least effective ED
> drug out there, as well as the one which is most likely to cause penile
> pain.
>
> My suggestion: Take what the doctor ordered and see what happens.
>
> Jim


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