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Author Trimix success
dgmoore@erols.com

2006-09-03, 4:22 pm

A couple of weeks ago I reported that, after all other meds (V, C, L,
Muse, Caverject, Edex,) had failed, my uro tried a test shot of Trimix
in his office with little success (my ED has gotten progressively worse
over the past 5 years and has now become total).

At the same time, I reported to my internist that, having lost over 30
pounds, I seem to be overmedicated for blood pressure as evidenced by
several bouts of low BP (80s over 50s). He agreed and eliminated one of
my meds (HCTZ) and cut the other two in half (Toprol XL and Cozaar).

Last night, with little expectation of success, I took 20 mg of Levitra
followed an hour later with with .5 cc of trimix. About 30 minutes
later I wasn't noticing much response, but my wife finished her shower
and came to bed, and much to my surprise, everthing worked - we had the
best (and only successful) encounter in over a year.

I had pretty much given up on the pharmaceutical approach and had
decided to go for an implant, but now I think I'll give Trimix a few
more tries and see if this remains consistent.

Even if the trimix continues to work, I still need surgery to correct a
problem with Peyronies disease - we have tried to treat it medically
for over two years with no success. While it is not quite severe enough
to prevent sex, it causes enough discomfort to make me want to get it
fixed. If I'm having surgery anyway, and with the likelihood that
trimix won't work for me forever, I still think it might make sense to
go ahead with the implant anyway. The idea of two closely related
surgeries in succession doesn't make much sense to me - I might as well
get the whole thing done at once.

Any thoughts?

Thanks
Dave

LMac

2006-09-03, 4:22 pm

Thoughts? Absolutely: Congratulations Dave!
Suggest give the body a good three months to adjust to the new med
regimen. Lots of tissue changes to be made. Hope the BP stays in
control for you.
It's hard to give up a winning combination but you might try
dialing down the Levitra a bit as well. ...Lmac

dgmoore@erols.com wrote:
> A couple of weeks ago I reported that, after all other meds (V, C, L,
> Muse, Caverject, Edex,) had failed, my uro tried a test shot of Trimix
> in his office with little success (my ED has gotten progressively worse
> over the past 5 years and has now become total).
>
> At the same time, I reported to my internist that, having lost over 30
> pounds, I seem to be overmedicated for blood pressure as evidenced by
> several bouts of low BP (80s over 50s). He agreed and eliminated one of
> my meds (HCTZ) and cut the other two in half (Toprol XL and Cozaar).
>
> Last night, with little expectation of success, I took 20 mg of Levitra
> followed an hour later with with .5 cc of trimix. About 30 minutes
> later I wasn't noticing much response, but my wife finished her shower
> and came to bed, and much to my surprise, everthing worked - we had the
> best (and only successful) encounter in over a year.
>
> I had pretty much given up on the pharmaceutical approach and had
> decided to go for an implant, but now I think I'll give Trimix a few
> more tries and see if this remains consistent.
>
> Even if the trimix continues to work, I still need surgery to correct a
> problem with Peyronies disease - we have tried to treat it medically
> for over two years with no success. While it is not quite severe enough
> to prevent sex, it causes enough discomfort to make me want to get it
> fixed. If I'm having surgery anyway, and with the likelihood that
> trimix won't work for me forever, I still think it might make sense to
> go ahead with the implant anyway. The idea of two closely related
> surgeries in succession doesn't make much sense to me - I might as well
> get the whole thing done at once.
>
> Any thoughts?
>
> Thanks
> Dave
>

Muerta

2006-09-04, 4:23 pm


<dgmoore@erols.com> wrote in message
news:1157304242.643165.240190@74g2000cwt.googlegroups.com...
> . He agreed and eliminated one of
> my meds (HCTZ)


*Big step up!*


>and cut the other two in half (Toprol XL and Cozaar).
>


OK, you were on a thiazide diuretic *and* a beta blocker?

And you are here wondering why you can't get an erection?

I don't know if you had lurked long, or read anything about how your meds
affect sexual performance, but either one of those drugs can make you go
limp by themselves. Combined.............

No doubt that eliminating the HVTZ let you finally get a little bit of
function. Although I have recently seen a dissenting opinion that I trust,
the majority of people have had very good results with cozaar, and it is
reported to be a very pro-sexual drug.

The toprol XL, however, is a beta blocker. You may want to discuss with your
doc about trying replacing the toprol XL with a calcium channel blocker,
even if he has to up the dosage of the cozaar again.

A penile implant is forever, man. There's no going back.

How does your hormone panel look?


Peabody

2006-09-04, 4:23 pm

dgmoore@erols.com says...

> Even if the trimix continues to work, I still need
> surgery to correct a problem with Peyronies disease - we
> have tried to treat it medically for over two years with
> no success. While it is not quite severe enough to
> prevent sex, it causes enough discomfort to make me want
> to get it fixed. If I'm having surgery anyway, and with
> the likelihood that trimix won't work for me forever, I
> still think it might make sense to go ahead with the
> implant anyway. The idea of two closely related
> surgeries in succession doesn't make much sense to me -
> I might as well get the whole thing done at once.


> Any thoughts?


Yes indeed.

When you say you've treated the Peyronie's medically, was
that with a urologist who specializes in Peyronie's? Did it
include verapamil injections? Well, I'm certainly no
expert, but my understanding is that among doctors there is
a very wide variance in competence to treat that disease.
So if you haven't searched for the world's foremost
authority on this in your area, you might want to do that
before surgery.

Also, you may find that if you eliminate the beta blocker as
well as the thiazide diuretic, you may not even need the
trimix, let alone an implant.

Personally, I wouldn't have either of those surgeries
except as an absolute last resort, and only after something
like a fourth opinion. But that's just me.

Good luck. Let us know what happens.

dgmoore@erols.com

2006-09-04, 4:23 pm

My ED started before the BP meds and was succesfully combatted by C, V,
L. After I started on HCTZ, Toprol, Cozaar I had no increase in ED
problems for a couple of years. When V, C, L stopped working I
immediately consulted my internist and urologist. Both believe that my
ED is not related to the BP meds. I then consulted a leading urolgist
specializing in ED and Peyronies - a professor at the U of MD Medical
Center in Baltimore - who gave me a thorough workup and in the end
agreed that the BP meds were not causing my problem. The consensus is
that I have nerve and/or vascular damage from diabetes.

Believe me, I am in no great rush to have surgery, but I have several
medical opinions that surgery is indicated in my case.

I'm not going to do anything at all for a while - I want to see if I
can continue to get results with the trimix, or if it's going to fizzle
in a little while, just like the V, C, L did...

Thanks
Dave

Muerta wrote:
> <dgmoore@erols.com> wrote in message
> news:1157304242.643165.240190@74g2000cwt.googlegroups.com...
>
> *Big step up!*
>
>
>
> OK, you were on a thiazide diuretic *and* a beta blocker?
>
> And you are here wondering why you can't get an erection?
>
> I don't know if you had lurked long, or read anything about how your meds
> affect sexual performance, but either one of those drugs can make you go
> limp by themselves. Combined.............
>
> No doubt that eliminating the HVTZ let you finally get a little bit of
> function. Although I have recently seen a dissenting opinion that I trust,
> the majority of people have had very good results with cozaar, and it is
> reported to be a very pro-sexual drug.
>
> The toprol XL, however, is a beta blocker. You may want to discuss with your
> doc about trying replacing the toprol XL with a calcium channel blocker,
> even if he has to up the dosage of the cozaar again.
>
> A penile implant is forever, man. There's no going back.
>
> How does your hormone panel look?


Jim

2006-09-05, 4:23 pm


dgmoore@erols.com wrote:
....The consensus is
> that I have nerve and/or vascular damage from diabetes.
>
> Believe me, I am in no great rush to have surgery, but I have several
> medical opinions that surgery is indicated in my case.
>
> I'm not going to do anything at all for a while - I want to see if I
> can continue to get results with the trimix, or if it's going to fizzle
> in a little while, just like the V, C, L did...
>
> Thanks
> Dave


________

You didn't mention having diabetes earlier. That adds a complication,
too. You have hypertension, diabetes, and Peyronie's, all three of
which can cause or contribute to ED.

But, if you have had a good experience on T-mix and you have a good
doctor helping you along with dosage levels of that and perhaps mixing
in one of the pill drugs, you have a good shot at getting some years of
satisfactory erectile function.

I'd suggest you look carefully into some of the new treatments for
Peyronie's (including surgical proceedures of which there are several)
before you make a decision. If you can get results from the T-mix and,
say, some pill help, you could postpone the implant surgery for the
time when nothing at all may be working.

Jim

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