Impotence Support

Author

Vera Abbott

2005-09-23, 5:47 pm

Hi; has any one here taken any medication, i.e. cardizem(?) that has caused
ED, and been able to overcome the problem? My partner had a mini stroke 6
yrs ago, and was given that. My doctor says "cardizem would not have caused
the problem. It was something else.", yet I have a book that says cardizem
can do it.
Jarta65@shaw.ca

2005-09-23, 5:47 pm

Vera Abbott wrote:
> Hi; has any one here taken any medication, i.e. cardizem(?) that has caused
> ED, and been able to overcome the problem? My partner had a mini stroke 6
> yrs ago, and was given that. My doctor says "cardizem would not have caused
> the problem. It was something else.", yet I have a book that says cardizem
> can do it.
> Jarta65@shaw.ca
>
>
Biovail's web site lists "impotence" as a reported side effect. Go to:
<http://www.cardizemla.com/pi.asp> and click on "prescribing
information." It doesn't appear with any percentage of incidence so is
shown as a "minor" or "other" effect. That may mean it was reported
anecdotally rather than being an item of investigation during the
trials. The trial folks may not have asked any questions of male trial
subjects regarding ED. Or, their population wasn't very sexually active
during the trial and the issue never surfaced as statistically significant.

Remember too that a stroke or TIA may damage the neurological pathways
that help complete the stimulation-to-erection circuitry. I've had
several small sensory TIAs over the past five years. My obvious TIAs
have usually been auditory or visual. At the same time, I've noted that
some of the old stimulation paths haven't worked as they once did.
Fortunately, the good lord gave us more that one way to skin a cat and
my wife is able to explore some alternatives that do work.

PJ

Peabody

2005-09-23, 5:47 pm

Vera Abbott says...

> Hi; has any one here taken any medication, i.e.
> cardizem(?) that has caused ED, and been able to
> overcome the problem? My partner had a mini stroke 6 yrs
> ago, and was given that. My doctor says "cardizem would
> not have caused the problem. It was something else.",
> yet I have a book that says cardizem can do it.

I take 300 mg per day, and I don't believe it has caused
that problem. I've been off of it a few times while trying
other drugs, and didn't notice any change during those
periods.

However, diltiazem (the generic name) can result in a
buildup of estrogen in some men, which could indirectly
result in ED, and even gynecomastia (breast development).
The drug is a moderate Cytochrome P450-3A4 inhibitor, and
can reduce the rate at which estrogens are metabolized and
removed from the body.

It's not clear to me why your partner is taking Cardizem.
Is it to treat high blood pressure? If so, you could try
switching to another kind of med for a few months to see if
it makes any difference. Maybe an ARB (angiotensin receptor
blocker) like losartan, which shouldn't cause problems, and
is thought by some to actually benefit sexual function.

Muerta

2005-09-24, 7:58 am

"Vera Abbott" <Jarta65@shaw.ca> wrote in message
news:mOgXe.511929$s54.263391@pd7tw2no...
> Hi; has any one here taken any medication, i.e. cardizem(?) that has
> caused ED, and been able to overcome the problem? My partner had a mini
> stroke 6 yrs ago, and was given that. My doctor says "cardizem would not
> have caused the problem. It was something else.", yet I have a book that
> says cardizem can do it.
> Jarta65@shaw.ca
>
>

I was on cardizem for an irregular heart beat for about 6 mos., then
switched to cartia and have used it since.

I'm pretty senisitive to drugs and ED, and have not had a single problem
with it.

We all react differently, however.

Jarta65

2005-09-26, 4:58 pm

I'm not certain if PJ got my reply or not, but in '99 my partner was found
to have a small cyst in his left lung, and had 1/4 of the lung removed, then
shortly thereafter, he had a mini-strke. I can't remember what all was
prescribed, but cardizem was one. He became forgetful, often taking the car
downtown, and coming back without it, having forgotten where he left it. He
quit taking all of the meds, because he was becoming terrified of what was
happening, and the doctor was no help at all. Jarta65
"Peabody" <waybackKILLSPAM44@yahoo.com> wrote in message
news:v8lXe.83129$Zp.72008@lakeread04...
> Vera Abbott says...
>
>
> I take 300 mg per day, and I don't believe it has caused
> that problem. I've been off of it a few times while trying
> other drugs, and didn't notice any change during those
> periods.
>
> However, diltiazem (the generic name) can result in a
> buildup of estrogen in some men, which could indirectly
> result in ED, and even gynecomastia (breast development).
> The drug is a moderate Cytochrome P450-3A4 inhibitor, and
> can reduce the rate at which estrogens are metabolized and
> removed from the body.
>
> It's not clear to me why your partner is taking Cardizem.
> Is it to treat high blood pressure? If so, you could try
> switching to another kind of med for a few months to see if
> it makes any difference. Maybe an ARB (angiotensin receptor
> blocker) like losartan, which shouldn't cause problems, and
> is thought by some to actually benefit sexual function.
>
>