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| Abstract. The bactericidal action of silver (0) nanoparticles and
amoxicillin on Escherichia coli is studied, respectively. Increasing
concentration of both amoxicillin (0–0.525 mg ml-1) and silver
nanoparticles (0–40 µg ml-1) showed a higher antibacterial effect in
Luria–Bertani (LB) medium. Escherichia coli cells have different
bactericidal sensitivity to them. When amoxicillin and silver
nanoparticles are combined, it results in greater bactericidal
efficiency on Escherichia coli cells than when they were applied
separately. Dynamic tests on bacterial growth indicated that
exponential and stationary phases are greatly decreased and delayed in
the synergistic effect of amoxicillin and silver nanoparticles. In
addition, the effect induced by a preincubation with silver
nanoparticles is examined. The results show that solutions with more
silver nanoparticles have better antimicrobial effects. One
hypothesized mechanism is proposed to explain this phenomenon.
http://www.iop.org/EJ/abstract/0957-4484/16/9/082
In other words silver is an ESSENTIAL supplement.
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