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Home > Archive > Pathology > April 2006 > Complete removal of iron / epilepsy
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Complete removal of iron / epilepsy
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| ironjustice@aol.com 2006-04-04, 11:43 am |
| <<snip>>
complete removal of cavernoma-surrounding hemosiderin-stained brain
tissue may improve epileptic outcome
<<snip>>
Seizure Outcome after Resection of Cavernous Malformations Is Better
When Surrounding Hemosiderin-stained Brain Also Is Removed.
Baumann CR, Schuknecht B, Lo Russo G, Cossu M, Citterio A, Andermann F,
Siegel AM
Epilepsia. 2006 Mar ; 47(3): 563-6
Summary: Purpose: Considering the epileptogenic effect of
cavernoma-surrounding hemosiderin, assumptions are made that resection
only of the cavernoma itself may not be sufficient as treatment of
symptomatic epilepsy in patients with cavernous malformations. The
purpose of this study was to test the hypothesis whether seizure
outcome after removal of cavernous malformations may be related to the
extent of resection of surrounding hemosiderin-stained brain tissue.
Methods: In this retrospective study, 31 consecutive patients with
pharmacotherapy-refractory epilepsy due to a cavernous malformation
were included. In all patients, cavernomas were resected, and all
patients underwent pre- and postoperative magnetic resonance imaging
(MRI). We grouped patients according to MRI findings (hemosiderin
completely removed versus not/partially removed) and compared seizure
outcome (as assessed by the Engel Outcome Classification score) between
the two groups. Results: Three years after resection of cavernomas,
patients in whom hemosiderin-stained brain tissue had been removed
completely had a better chance for a favorable long-term seizure
outcome compared with those with detectable postoperative hemosiderin
(p = 0.037). Conclusions: Our study suggests that complete removal of
cavernoma-surrounding hemosiderin-stained brain tissue may improve
epileptic outcome after resection of cavernous malformations.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking
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| So, translate that into Canadian English, Bub, not doctorese.
--
===========================================
Paul J. Chiasson
http://www3.ns.sympatico.ca/paul.chiasson/
paul.chiasson@ns.sympatico.ca
vsmon@ns.sympatico.ca
ai714@chebucto.ns.ca
==========================================
<ironjustice@aol.com> wrote in message
news:1144144912.061905.320050@t31g2000cwb.googlegroups.com...
> <<snip>>
> complete removal of cavernoma-surrounding hemosiderin-stained
> brain
> tissue may improve epileptic outcome
> <<snip>>
>
> Seizure Outcome after Resection of Cavernous Malformations Is
> Better
> When Surrounding Hemosiderin-stained Brain Also Is Removed.
> Baumann CR, Schuknecht B, Lo Russo G, Cossu M, Citterio A,
> Andermann F,
> Siegel AM
> Epilepsia. 2006 Mar ; 47(3): 563-6
>
> Summary: Purpose: Considering the epileptogenic effect of
> cavernoma-surrounding hemosiderin, assumptions are made that
> resection
> only of the cavernoma itself may not be sufficient as treatment
> of
> symptomatic epilepsy in patients with cavernous malformations.
> The
> purpose of this study was to test the hypothesis whether
> seizure
> outcome after removal of cavernous malformations may be related
> to the
> extent of resection of surrounding hemosiderin-stained brain
> tissue.
> Methods: In this retrospective study, 31 consecutive patients
> with
> pharmacotherapy-refractory epilepsy due to a cavernous
> malformation
> were included. In all patients, cavernomas were resected, and
> all
> patients underwent pre- and postoperative magnetic resonance
> imaging
> (MRI). We grouped patients according to MRI findings
> (hemosiderin
> completely removed versus not/partially removed) and compared
> seizure
> outcome (as assessed by the Engel Outcome Classification score)
> between
> the two groups. Results: Three years after resection of
> cavernomas,
> patients in whom hemosiderin-stained brain tissue had been
> removed
> completely had a better chance for a favorable long-term
> seizure
> outcome compared with those with detectable postoperative
> hemosiderin
> (p = 0.037). Conclusions: Our study suggests that complete
> removal of
> cavernoma-surrounding hemosiderin-stained brain tissue may
> improve
> epileptic outcome after resection of cavernous malformations.
>
> Who loves ya.
> Tom
>
>
> Jesus Was A Vegetarian!
> http://jesuswasavegetarian.7h.com
>
>
> Man Is A Herbivore!
> http://pages.ivillage.com/ironjustice/manisaherbivore
>
>
> DEAD PEOPLE WALKING
> http://pages.ivillage.com/ironjustice/deadpeoplewalking
>
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| Nah! Jesus ate my cinnamon rolls, cabbage rolls, and egg rolls.
He was always one for "Rollin' On Down the Highway" of life.
--
===========================================
Paul J. Chiasson
http://www3.ns.sympatico.ca/paul.chiasson/
paul.chiasson@ns.sympatico.ca
vsmon@ns.sympatico.ca
ai714@chebucto.ns.ca
==========================================
<ironjustice@aol.com> wrote in message
news:1144521483.722325.301670@i39g2000cwa.googlegroups.com...
>
> In the animal model of epilepsy they induce epilepsy BY ..
> introduction
> of iron into the brain of the animal.
>
> Sooooo.. it comes of no 'surprise' that BY removal of iron /
> hemosiderin .. there is functional / improved .. recovery ..
> when in
> FACT the iron is what is causing the epilepsy to begin .. with
> ..
>
> But 'they' will argue that .. fact ..
>
> Who loves ya.
> Tom
>
>
> Jesus Was A Vegetarian!
> http://jesuswasavegetarian.7h.com
>
>
> Man Is A Herbivore!
> http://pages.ivillage.com/ironjustice/manisaherbivore
>
>
> DEAD PEOPLE WALKING
> http://pages.ivillage.com/ironjustice/deadpeoplewalking
>
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