| ironjustice@aol.com 2006-03-22, 3:41 pm |
| Decreased plasma antioxidants in patients with Alzheimer's disease.
Kim TS, Pae CU, Yoon SJ, Jang WY, Lee NJ, Kim JJ, Lee SJ, Lee C, Paik
IH, Lee CU
Int J Geriatr Psychiatry. 2006 Mar 13;
OBJECTIVES: It has been suggested that oxidative injuries have an
important role in the pathogenesis of Alzheimer's disease (AD). In this
study, we assess whether the plasma levels of albumin, bilirubin, and
uric acid would be altered in the AD patients compared to those of the
healthy controls. Furthermore, we tried to find the correlations
between plasma antioxidant levels and the cognitive function in AD
patients. METHODS: The plasma albumin, bilirubin, and uric acid levels
were measured by standard methods in 101 AD patients and 101 healthy
controls. The Korean version of the Mini Mental Status Examination
(MMSE-K) was used to evaluate the cognitive functions of AD patients.
RESULTS: A significant reduction in the albumin, bilirubin, and uric
acid levels in the AD group was found compared to those of the control
group. The scores of MMSE-K showed the positive correlation with
albumin level in the AD group after adjusting confounding factors such
as body mass index, gender and age. CONCLUSION: This study showed that
oxidative injuries could be involved in the pathogenesis of AD, as well
as indicating that some antioxidant might be associated with the
cognitive functions in AD. Copyright (c) 2006 John Wiley & Sons, Ltd.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking
|