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Home > Archive > Pathology > May 2005 > Multiple trauma / N-6 polynsaturated fatty acids
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Multiple trauma / N-6 polynsaturated fatty acids
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| ironjustice@aol.com 2005-05-02, 5:52 pm |
| Prostaglandins Leukot Essent Fatty Acids. 2005 May;72(5):357-62.
Related Articles, Links
N-6 polynsaturated fatty acids confer hemodynamic stability in an
experimental model of multiple trauma.
Efstathopoulos N, Bathrellos E, Giamarellos-Bourboulis EJ, Lazarettos
J, Papalois A, Grecka P, Nikolaou V.
2nd Department of Orthopaedics, university of Athens, Medical School,
Greece.
Immunonutrition with diets enriched in polyunsaturated fatty acids
(PUFAs) are becoming mandatory for multiple trauma patients. Solutions
containing single n-6 PUFAs were administered intravenously in an
experimental model of trauma. Thirty-five rabbits were studied; 13
controls; 10 administered gamma-linolenic acid (GLA) 30 min after
fracture of the right femor; and 12 arachidonic acid (AA). Systolic,
diastolic and mean arterial pressures and heart rate were recorded;
serum levels of tumor necrosis factor-alpha (TNFalpha), malondialdehyde
(MDA) and nitrate were estimated before and after therapy. Mean
survival of controls, of animals treated with GLA and of animals
treated with AA was 0.80, 1.41 and 3.60 days, respectively.
Administration of PUFAs induced higher levels of blood pressure; that
of AA decreased serum TNFalpha and tissue bacterial load compared to
controls. Intravenous administration of n-6 PUFAs conferred hemodynamic
stability and increased survival in a model of trauma rendering further
research mandatory.
PMID: 15850717 [PubMed - in process]
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Who loves ya.
Tom
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| montygram 2005-05-02, 5:52 pm |
| This is an interesting study, and consistent with what I have been
saying about Eskimos and their high consumptions of omega 3 PUFAs.
PUFAs are powerful, like medication. The omega 3s are bad for trauma,
which anyone who knows about the high death rates among Eskimos on
tradtional diets (often due to minor blunt force trauma) realizes. The
omega 6 PUFAs, of which arachidonic is the most potent, have the
opposite effect. They ramp up blood pressure, promote clotting, etc.
A study I saw on yahoo health yesterday made the point, only they were
saying you don't want this on a regular basis - otherwise, you will
have high blood pressure. Never confuse pathological conditions with
maintaining health - would you take chemotherapy to prevent cancer?
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| Andrew Heenan 2005-05-02, 5:52 pm |
| "montygram" <nazztrader@lycos.com>
> Is a crossposting idiot.
> Stop crossposters by using this message as
> a reply to all groups *except your own*,
> then block the sender (killfile).
> It takes a few seconds to excommunicate
> the idiots, and the more people that do it,
> the sooner they'll learn.
> Keep The Internet Free - of Idiots
Andrew
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| Robert 2005-05-02, 10:54 pm |
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"Andrew Heenan" <andrew4@heenan.net> wrote in message
news:d56a25$h2p$1@news7.svr.pol.co.uk...
> "montygram" <nazztrader@lycos.com>
>
> Andrew
Andrew, will you please stop crossposting.
>
>
>
>
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| Robert 2005-05-02, 10:54 pm |
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<ironjustice@aol.com> wrote in message
news:1115055557.819391.18380@f14g2000cwb.googlegroups.com...
> Prostaglandins Leukot Essent Fatty Acids. 2005 May;72(5):357-62.
> Related Articles, Links
>
>
Are you saying that people should have a diet rich in 6 Puff's before they
have multiple trauma?
That last one is a good point, "homodynamic
stability and increased survival in a model of trauma rendering further
research mandatory."
Why is that mandatory if they already proved it?
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