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Increased erythropoiesis / red blood cells / metabolic syndrome
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| ironjustice@aol.com 2005-06-06, 11:52 am |
| http://tinyurl.com/82q4g
<<snip>>
We conclude that enhanced erythropoiesis could be a new, hitherto
unrecognized component of the metabolic syndrome.
<<snip>>
Diabetes Research and Clinical Practice
Article in Press, Corrected Proof - Note to users
doi:10.1016/j.diabres.2005.01.005
Copyright =A9 2005 Elsevier Ireland Ltd All rights reserved.
Increased erythropoiesis and subclinical inflammation as part of the
metabolic syndrome
T=2E Mardia, d, e, S. Tokera, b, d, e, S. Melamedc, d, e, A. Shiromb, e,
D=2E Zeltsera, d, e, I. Shapiraa, d, e, S. Berlinera, d, e, , and O.
Rogowskia, d, e
aDepartment of Medicine "D" and Institute for Special Medical
Examinations (MALRAM), Tel Aviv Sourasky Medical Center, Tel Aviv,
affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel
Aviv, 6 Weizman Street, Tel Aviv 64239, Israel
bFaculty of Management, Tel Aviv University, Tel Aviv, Israel
cNational Institute of Occupational and Environmental Health, Raanana,
Israel
dSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
eTel Aviv Medical Center Inflammation Survey (TAMCIS) Group, Tel Aviv,
Israel
Received 7 June 2004; revised 25 November 2004; accepted 10 January
2005. Available online 3 March 2005.
Abstract
Recent studies have suggested the insulin resistance might be
accompanied by enhanced erythropoiesis. We have examined this
association in individuals with the metabolic syndrome (MS) who in
addition to insulin resistance harbor a chronic low grade inflammation.
This study is relevant because chronic inflammation might have a
suppressive effect on erythropoiesis. 280 and 554 non-smoking women and
men with respective age of 46.4 =B1 9.3 (mean =B1 S.D.) and 44.0 =B1 11.0
years are included. A significant correlation was noted between the
numbers of the components of the MS and the inflammatory biomarkers
including the white blood cell count, high sensitivity C-reactive
protein, fibrinogen concentrations and the erythrocyte sedimentation
rate. In addition, a significant correlation (r =3D 0.157, p =3D 0.008) was
noted between the number of components of the MS and the number of red
blood cells in the peripheral blood in women. The same was true for men
(r =3D 0.192, p < 0.0005). We conclude that enhanced erythropoiesis could
be a new, hitherto unrecognized component of the MS. The enhanced
erythropoiesis could give an erroneous impression of general "good"
health in these individuals.
Keywords: Erythropoiesis; Metabolic syndrome; Inflammation
Abbreviations: MS, metabolic syndrome; TAMCIS, Tel Aviv Medical Center
Inflammation Survey; WBCC, white blood cell count; ESR, erythrocyte
sedimentation rate; hs-CRP, high sensitivity C-reactive protein; HOMA,
homeostasis model assessment; BMI, body mass index; RBC, red blood
cells; PMN, polymorphonuclears; BP, blood pressure
Corresponding author. Tel.: +972 3 6973133; fax: +972 3 6974961.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.=ADcom
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DEAD PEOPLE WALKING
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| |
| Herman Rubin 2005-06-06, 5:54 pm |
| In article <1118076665.057228.301960@f14g2000cwb.googlegroups.com>,
ironjustice@aol.com <ironjustice@aol.com> wrote:
>http://tinyurl.com/82q4g
><<snip>>
>We conclude that enhanced erythropoiesis could be a new, hitherto
>unrecognized component of the metabolic syndrome.
><<snip>>
>Diabetes Research and Clinical Practice
>Article in Press, Corrected Proof - Note to users
>doi:10.1016/j.diabres.2005.01.005
>Copyright =A9 2005 Elsevier Ireland Ltd All rights reserved.
>Increased erythropoiesis and subclinical inflammation as part of the
>metabolic syndrome
>T=2E Mardia, d, e, S. Tokera, b, d, e, S. Melamedc, d, e, A. Shiromb, e,
>D=2E Zeltsera, d, e, I. Shapiraa, d, e, S. Berlinera, d, e, , and O.
>Rogowskia, d, e
<aDepartment of Medicine "D" and Institute for Special Medical
<Examinations (MALRAM), Tel Aviv Sourasky Medical Center, Tel Aviv,
<affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel
<Aviv, 6 Weizman Street, Tel Aviv 64239, Israel
<bFaculty of Management, Tel Aviv University, Tel Aviv, Israel
<cNational Institute of Occupational and Environmental Health, Raanana,
<Israel
<dSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
<eTel Aviv Medical Center Inflammation Survey (TAMCIS) Group, Tel Aviv,
<Israel
>Received 7 June 2004; revised 25 November 2004; accepted 10 January
>2005. Available online 3 March 2005.
>Abstract
>Recent studies have suggested the insulin resistance might be
>accompanied by enhanced erythropoiesis. We have examined this
>association in individuals with the metabolic syndrome (MS) who in
>addition to insulin resistance harbor a chronic low grade inflammation.
>This study is relevant because chronic inflammation might have a
>suppressive effect on erythropoiesis. 280 and 554 non-smoking women and
>men with respective age of 46.4 =B1 9.3 (mean =B1 S.D.) and 44.0 =B1 11.0
>years are included. A significant correlation was noted between the
>numbers of the components of the MS and the inflammatory biomarkers
>including the white blood cell count, high sensitivity C-reactive
>protein, fibrinogen concentrations and the erythrocyte sedimentation
>rate. In addition, a significant correlation (r =3D 0.157, p =3D 0.008) was
>noted between the number of components of the MS and the number of red
>blood cells in the peripheral blood in women. The same was true for men
>(r =3D 0.192, p < 0.0005). We conclude that enhanced erythropoiesis could
>be a new, hitherto unrecognized component of the MS. The enhanced
>erythropoiesis could give an erroneous impression of general "good"
>health in these individuals.
These correlations have STATISTICAL significance, but very
little PRACTICAL significance. Nor do they indicate anything
causal in either direction.
--
This address is for information only. I do not claim that these views
are those of the Statistics Department or of Purdue University.
Herman Rubin, Department of Statistics, Purdue University
hrubin@stat.purdue.edu Phone: (765)494-6054 FAX: (765)494-0558
| |
| ironjustice@aol.com 2005-06-06, 10:52 pm |
| >Nor do they indicate anything
causal in either direction. <
Increased erythropoiesis .. has been shown to INCREASE .. viscosity ..
Viscosity of the blood HAS been shown to be related to .. health ..
So .. technically .. increased erythropoiesis .. HAS .. been found to
BE related TO .. disease .. DUE TO .. the INCREASE in viscosity ..
But that comes from just KNOWING .. what .. the outcomes .. OF ..
increased viscosity and / or of the increased erythropoiesis ..
Increased viscosity has been shown to result in the symptoms of ..
inflammation ..
Evidenced BY the accidental use of 'too thick' of substituted food in
the feeding line ..
Oops ..
Mysterious .. ways ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.=ADcom
Man Is A Herbivore!
http://pages.ivillage.com/iron=ADju...manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/iron=ADju...adpeoplewalking
| |
|
| On 6 Jun 2005 20:23:41 -0700, "ironjustice@aol.com"
<ironjustice@aol.com> Huffed and Puffed the following into the madness
of usenet:
>causal in either direction. <
>
>
>Increased erythropoiesis .. has been shown to INCREASE .. viscosity ..
>
>Viscosity of the blood HAS been shown to be related to .. health ..
>
>So .. technically .. increased erythropoiesis .. HAS .. been found to
>BE related TO .. disease .. DUE TO .. the INCREASE in viscosity ..
>
>But that comes from just KNOWING .. what .. the outcomes .. OF ..
>increased viscosity and / or of the increased erythropoiesis ..
>
>Increased viscosity has been shown to result in the symptoms of ..
>inflammation ..
>
>Evidenced BY the accidental use of 'too thick' of substituted food in
>the feeding line ..
>
>Oops ..
>
>Mysterious .. ways ..
>
>Who loves ya.
>Tom
I don't think anyone could have shown how insane tom aka ironjustice
really is any better than this post did.
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| ironjustice@aol.com 2005-06-07, 8:54 am |
| Nephron. 1992;61(2):214-6. Related Articles, Links
Phlebotomy for erythropoietin-induced malignant hypertension.
Fahal IH, Yaqoob M, Ahmad R.
Regional Renal Unit, Royal Liverpool University, UK.
Four patients on regular dialysis treatment whose blood pressure was
well controlled, developed malignant hypertension while receiving
maintenance recombinant human erythropoietin (r-Hu-EPO). None of these
patients had a haematocrit greater than 35% at any stage, and
clinically, none had any evidence of fluid overload. Initially, they
were all managed by stopping r-Hu-EPO and intensification of
antihypertensive therapy. However, none of the patients responded, and
venesection of 500 ml of blood was performed in each case with swift
and sustained response.
Publication Types:
Case Reports
PMID: 1630548 [PubMed - indexed for MEDLINE]
---------------------------------------------------------------------------=
-----
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.=ADcom
Man Is A Herbivore!
http://pages.ivillage.com/iron=ADju...manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/iron=ADju...adpeoplewalking
| |
|
| In article <gp6ba1lmg69o8lkk8ajhm76ea7epif49k0@4ax.com>,
Ma?k <youknow@yourenutty.com> wrote:
> On 6 Jun 2005 20:23:41 -0700, "ironjustice@aol.com"
> <ironjustice@aol.com> Huffed and Puffed the following into the madness
> of usenet:
>
>
>
>
> I don't think anyone could have shown how insane tom aka ironjustice
> really is any better than this post did.
>
>
I killfiled him on _all_ of my lists a long time ago. ;-)
--
K.
Sprout the MungBean to reply
"I don't like to commit myself about heaven and hell--you
see, I have friends in both places." --Mark Twain
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