Drugs psychedelic - Clearing up misconceptions regarding LSD.

Author

Clearing up misconceptions regarding LSD.

Zxotch

2006-01-08, 11:37 am

This may end up being crossposted or seperately posted to different
groups. I apologize, but my newsreader has been acting strange lately.

While I am by no means uninitiated in terms of having taken LSD and
myriad other psychedelics in general, I am fairly unclear on how LSD in
particular affects the chemical processes in my brain. Of course, there
is a wealth of information regarding just this subject all over the
internet. However, I must stress that I am not a professional chemist.
I therefore come here, to a.d.p, in the hopes that some of you
Leary-esque gurus can "break it down for me."

Let me start by explaining it as I understand it. I am under the notion
that LSD stimulates the seratonin receptors in one's brain. These same
receptors are responsible for managing input from other senses, such as
sight and sound. Since they are being overstimulated, they produce the
various distortions one may note during a trip, such as trails, so on,
and so forth.

Although I also have only a very cursory understanding of
schizophrenia, I have been told that LSD causes a chemical reaction
that is not unlike schizophrenia. And that one may safely describe an
acid trip as "becoming severely schizophrenic." Is this true?

My third question is somewhat personal and specific, and also connected
to the previous question. When I was quite young, my mother was
diagnosed as a paranoid schizophrenic, with delusional tendencies.
Although it has been many, many years since that day, and I have never
shown any symptoms of mental illness, I often wonder if psychedelics
could aggravate this "genetic predilection." As I mentioned earlier, I
have tripped many times. I've also had my share of bad trips. I've
always dealt with the latter as well as can be expected, and have never
felt as though I was pushing myself too far mentally. However, I cannot
help but wonder if I am taking a dangerous risk in taking psychedelics,
LSD in particular.

Any advice from knowledgeable sources would be appreciated.

-----

The Edge... There is no honest way to explain it, because the only ones
who know where it is are the ones who have gone over.-- H.S. Thompson

Veszpertin - The Psychedelic Pope ~..~ His Most En

2006-02-25, 8:30 pm

LSD only remains in your body for 20 minutes
but it causes your brain to go into an 8 to 12 hour
supersensory mode in a neural loop over and over
again until it reaches its peak data input abilities
to obsorb the input data it is trying to consume
then as the peak happens at around 4 to 6 hours
the result of the brain shifting down again from overdrive to third
gear then second gear then first gear where you return to your normal
perceptive
self but with the memories of the entire events
occuring you become enlightened to details of things more clearly and
with a greater depth of
perception of all the input senses.

~xy~

2006-02-25, 8:30 pm

> with the memories of the entire events
> occuring you become enlightened to details of things more clearly and
> with a greater depth of
> perception of all the input senses.

O,
Yes,
Indeedy !

norway.stoner@gmail.com

2006-02-25, 8:30 pm

this link http://www.erowid.org/chemicals/lsd/lsd_faq.shtml should
clear up every question you may ever have about LSD with reputable
sources listed. It's the facts and not all the bs that floats around
the media, gov., schools, ect. Check it out you won't be disappointed i
promise. Because whats mentioned above isn't even close to correct.

hominid420

2006-02-28, 12:53 pm

"Zxotch" <awakenotdreaming@aol.com> wrote in message
news:1136587912.643498.63110@g47g2000cwa.googlegroups.com...
> This may end up being crossposted or seperately posted to different
> groups. I apologize, but my newsreader has been acting strange lately.
>
> While I am by no means uninitiated in terms of having taken LSD and
> myriad other psychedelics in general, I am fairly unclear on how LSD in
> particular affects the chemical processes in my brain. Of course, there
> is a wealth of information regarding just this subject all over the
> internet. However, I must stress that I am not a professional chemist.
> I therefore come here, to a.d.p, in the hopes that some of you
> Leary-esque gurus can "break it down for me."
>
> Let me start by explaining it as I understand it. I am under the notion
> that LSD stimulates the seratonin receptors in one's brain. These same
> receptors are responsible for managing input from other senses, such as
> sight and sound. Since they are being overstimulated, they produce the
> various distortions one may note during a trip, such as trails, so on,
> and so forth.

Not exactly correct. LSD is beleived to cause the brain to increase
production of, or the release of, the neurochemical dimethyltyptamine.
Dimethyltryptamine triggers R.E.M. sleep and is thought to be essential to
normal human thought processes. Dimethyltryptamine binds to a serotonin
receptor subtype, primarily in the recticular activating system; a structure
atop the brainstem which controls much of the way information is routed
around the brain.All receptor sites which bind to tryptophan derived
neurotransmiters are refered to as serotonin bindind sites even if serotonin
is only weakly active at that site. Because most research was shut down by
the government in the early 70's and dimethyltryptamine itself is a
prohibited substance, data is incomplete. One piece of information
discovered before this line of inquiry was shut down is that LSD is mostly
deactivated in the body within three to five hours after ingestion yet the
effects are just reaching their peak at this point. This implies that LSD
works indirectly by triggering a change in the availibility of the actual
active substance. Despite the heavy restrictions on psychedelic research;
LSD binding sites have been identified in the human brain, particularly in
the pineal gland. This structure regulates the metabolism off all tryptophan
derived neurotranmiters.

Futhermore; dimethyltryptamine can essentially be thought of as
'desoxypsilocin'; That is to say a psilocybin molecule resembles a
dimethyltryptamine molecule so closely it will bind to the same sites. The
level of psilocybin in the brain is directly related to the intensity of its
effect, unlike the case with LSD.

The last point on this portion of your posting is that although LSD is a
derivative of tryptophan, it has no close relation to any known
neurotrasmiter including both serotonin (5-hydroxytrptamine for compareson)
and dimethyltryptamine. Of course this makes you wonder just what the
recently discovered LSD binding sites are supposed to do.
>
> Although I also have only a very cursory understanding of
> schizophrenia, I have been told that LSD causes a chemical reaction
> that is not unlike schizophrenia. And that one may safely describe an
> acid trip as "becoming severely schizophrenic." Is this true?

Nope! Schizophrenia has only a superficial resembalence to LSD intoxication.
The neurochemical which triggers schizophrenia is known as dopamine
(3,4,hydroxy-phenylethylamine) and this is the neurotransmitter which
amphetamines boost. Speed is what will give you schizophernia! And you can
take that as an absolute fact. I did LSD for years and never had an adverse
psychological reaction lasting more than a few days at the very worst. I got
into methamphetamine and had a medically documented schizophrenic episode
lasting over a month and several relapses since, some with no drug use at
all. Now I have to take dopamine blocking medication every day or reality
starts to slip away and it all started with methamphetamine! If you're
worried about your mental health, stay away from all forms of speed. But
don't worry about LSD, its adverse reactions have been greatly exaggerated.
An adverse reaction to LSD is scary but rarely dangerous.
>
> My third question is somewhat personal and specific, and also connected
> to the previous question. When I was quite young, my mother was
> diagnosed as a paranoid schizophrenic, with delusional tendencies.
> Although it has been many, many years since that day, and I have never
> shown any symptoms of mental illness, I often wonder if psychedelics
> could aggravate this "genetic predilection." As I mentioned earlier, I
> have tripped many times. I've also had my share of bad trips. I've
> always dealt with the latter as well as can be expected, and have never
> felt as though I was pushing myself too far mentally. However, I cannot
> help but wonder if I am taking a dangerous risk in taking psychedelics,
> LSD in particular.

Like I said above, don't worry about LSD, but stay the hell away from speed!
>
> Any advice from knowledgeable sources would be appreciated.

I hope I didn't make it too complicated, but I don't know any simple way to
adequately answer your questions.
>
> -----
>
> The Edge... There is no honest way to explain it, because the only ones
> who know where it is are the ones who have gone over.-- H.S. Thompson
>

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