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New drug / controlling emotional outbursts
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| ironjustice@aol.com 2005-04-27, 8:52 am |
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Source: American Academy of Neurology (AAN) Released: Fri
01-Apr-2005, 11:00 ET
Embargo expired: Thu 14-Apr-2005, 13:30 ET
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Drug May Help MS Patients with Laughing, Crying Spells
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Description
A new drug may help people with multiple sclerosis (MS) who have a
condition that leaves them unable to control their emotions, according
to research.
Newswise - A new drug may help people with multiple sclerosis (MS)
who have a condition that leaves them unable to control their emotions,
according to research that will be presented at the American Academy of
Neurology 57th Annual Meeting in Miami Beach, Fla., April 9 - 16,
2005.
Called pseudobulbar affect, the condition results in episodes of
uncontrollable laughing or crying that may be inappropriate or not
related to the situation. The condition can also occur with other
neurological disorders such as amyotrophic lateral sclerosis (ALS),
Alzheimer's disease, stroke, and brain injury.
For the study, 150 people with MS and pseudobulbar affect received
either the drug AVP-923, which is a combination of the drugs
dextromethorphan hydrobromide and quinidine sulfate, or a placebo for
12 weeks. The study participants kept a diary tracking the number of
laughing/crying episodes they experienced each day, as well as any side
effects, and were assessed at four clinic visits.
Of those taking the drug, 84 percent reported improvement in the
condition, compared to 49 percent of those on placebo. Those taking the
drug had 46 percent fewer emotional episodes during the study than
those who received the placebo. They also reported overall improvement
in the condition and improvement in their quality of life, quality of
relationships, and amount of pain they experienced. Those taking the
drug reported the side effect of dizziness more often than those taking
the placebo did.
"This is the first drug designed specifically for this condition,"
said neurologist Hillel Panitch, MD, of the university of Vermont
College of Medicine in Burlington, VT. "The only treatment now is
antidepressants, which can have unpleasant side effects."
Panitch said the treatment showed improvements as early as the first
week of treatment.
The study was supported by Avanir Pharmaceuticals, which is developing
the drug AVP-923.
The American Academy of Neurology, an association of more than 18,000
neurologists and neuroscience professionals, is dedicated to improving
patient care through education and research. A neurologist is a doctor
with specialized training in diagnosing, treating and managing
disorders of the brain and nervous system such as Alzheimer's
disease, epilepsy, multiple sclerosis, Parkinson's disease, and
stroke.
For more information about the American Academy of Neurology, visit
http://www.aan.com.
Editor's Note: Dr. Panitch will present this research during a
scientific platform session at 1:30 p.m. on Thursday, April 14, in Room
A 101-105 of the Miami Beach Convention Center.
He will be available for media questions during a briefing at 10:00
a=2Em., Wednesday, April 13 in the on-site Press Interview Room, room
A107. All listed times are Eastern Time (ET).
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=A9 2005 Newswise. All Rights Reserved.
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Tom
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| Mary Fisher 2005-04-27, 11:49 am |
| Oh no, not here as well!
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| GT Tick 2005-04-27, 5:56 pm |
| Oh yeah, when Tommy boy gets frustrated from standing for hours in front
of the glory hole at the local public loo with no results he rushes home
to flog his keyboard in private.
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Re: New drug / controlling emotional outbursts
Group: alt.support.mult-sclerosis Date: Wed, Apr 27, 2005, 3:26pm
(CDT+6) From: mary.fisher@zetnet.co.uk (Mary=A0Fisher)
Oh no, not here as well!
*****Don't Cry Because It's Over...Smile Because It Happened.*****
Visit Me At Tick's Place...
http://community-2.webtv.net/OLTICK/TICKSPLACE/
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