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Author got my RX for Sativex today!!!!
bobbyD

2005-04-25, 5:51 pm

hi there folks

i picked up my RX for SATIVEX this morning from my doctor,, i will have my
rx filled and get the meds in approx 2-3 weeks,,, from my pharmacy.

i plan to test this medication like itested the synthetic crap,, meaning i
will onlu use sativex and not smoke,, unless it is useless and i get no help
from it,,,

bobbyD


Michael

2005-04-25, 10:50 pm

bobbyD wrote:

> hi there folks
>
> i picked up my RX for SATIVEX this morning from my doctor,, i will
> have my rx filled and get the meds in approx 2-3 weeks,,, from my
> pharmacy.
> i plan to test this medication like itested the synthetic crap,,
> meaning i will onlu use sativex and not smoke,, unless it is useless
> and i get no help from it,,,
>
> bobbyD


What's the Rx say, Bob? Dosage and whatnot?

Please call the pharmacy and get the pricing info, would you? I've been
pestering Bayer for weeks and they won't spill it... not to mention that
(see below) they told me only 6 days ago that they don't know when it will
be released for sale or how much they will charge for it.

((U))
M


----- Original Message -----
From: "MedInfo" <canada.medinfo@bayer.com>
To: <muirhead@haidagwaii.net>
Sent: Tuesday April 19, 2005 1:27 PM
Subject: Re: Sativex dosages, availability and retail pricing?


Thank you for your enquiry about Sativex®.


Sativex® has been developed by GW to provide a medically acceptable
cannabis-derived product for the treatment of the debilitating symptoms of
Multiple Sclerosis (MS) and severe neuropathic pain. The product is a whole
plant medicinal cannabis extract containing tetranabinex
(tetrahydrocannabinol -
THC) and nabidiolex (cannabidiol - CBD) as its principal components. The
medicine is administered by means of a spray into the mouth.


Approved in Canada on April 19, 2005, Sativex is the first cannabis-derived
pharmaceutical product ever approved as adjunctive treatment for relief of
neuropathic pain symptoms in Multiple Sclerosis.

Since its approval, Bayer HealthCare and GW Pharmaceuticals have been
focused on
finalizing distribution plans designed to ensure a sufficient and continuous
supply for Canadian patients living with Multiple Sclerosis.

We expect to have Sativex available through Canadian pharmacies in late
spring
of this year.

Sativex has been developed and is manufactured by GW pharmaceuticals, based
in
the UK. In Canada, Bayer HealthCare, Pharmaceuticals Division has the
exclusive
rights to market Sativex.

As with all controlled substances, highly specialized distribution
requirements
and controls must be put in place.
Bayer HealthCare will inform healthcare professionals and other stakeholders
in
a timely fashion on Sativex availability.


Since Sativex is a prescription drug in order to obtain it, you may have a
prescription from a Canadian physician.


If you want to learn more about Sativex, please visit GW Pharmaceuticals web
site at www.gwpharm.com


I hope this information is helpful. If you have further questions, please
contact Bayer Medical Information at 1-800-265-7382. Thank you for your
interest in Bayer pharmaceutical products.


Sincerely,




Olga NKÉMAIGNI, Pharm.D.
Healthcare Division
Bayer Inc.
77 Belfield Road
Toronto, Ontario, M9W 1G6
Medical Information /Drug Safety Specialist
Information Médicale/Innocuité des Médicaments
Tel: 1-800-265-7382
Fax: 1-866-232-0565




"Michael" <muirhead@haidagwaii.net> on 19/04/2005 03:23:00 PM

To: <canada.medinfo@bayer.com>
cc:

Subject: Sativex dosages, availability and retail pricing?

I have multiple sclerosis and I've been reading the press about your product
partnership with GW Pharmaceuticals and today's announcement of Sativex's
approval by Health Canada.

Can you tell me when this product is likely to be available in Canadian
pharmacies, what sort of dose-ranges are likely to be prescribed, and what
the approximate price (a ballpark figure is fine) of the product will be?
--
Michael Muirhead
Queen Charlotte City, BC









Dove 1

2005-04-25, 10:50 pm

Oh bobbyD - That sounds like a good plan -- I hope it is wonderful --
for you - and maybe later for all of us !
When you mentioned synthetic "crap" -do you mean the medicine that was
manufactured also from cannibus in a pill form ? Does it not work ?
I wish you relief from pain :-)))

Michael

2005-04-25, 10:50 pm

Dove 1 wrote:

> Oh bobbyD - That sounds like a good plan -- I hope it is wonderful --
> for you - and maybe later for all of us !
> When you mentioned synthetic "crap" -do you mean the medicine that was
> manufactured also from cannibus in a pill form ? Does it not work ?


Apparently, it does work, but how *well* it works is still sort of a trade
secret.

It's not in a pill form, but in a spray that you squirt under your tonguue
(or between cheek and gum)... it's absorbed there only a little slower than
by inhaling smoke - and it's less toxic because there are no combustion
products.

That said... it's going to be damned expensive compared to even the very
best bud on the planet. My guess (it's *only* a guess) is that it will be
over $3 per squirt-dose (2.7/2.5mg of THC/CBD).

For comparison, I get approximately the same dose of both compounds from
about 20mg of good bud. A quarter ounce of good bud (28 grams = 1400
"sativex-sized" doses) costs me $100 at most, which means I pay 7/10 of a
cent per dose (actually a *very* tiny dose: I usually smoke about 3 to 5
times that much at once, and I know Bob sometimes smokes the equivalent of
more than 100 "standard" Sativex doses at a go.)

If I pay 0.7 cents per "standard dose" and Sativex is going to cost $3 for
the same dose... that would make the cost of Sativex more than 420 times the
cost of the bud I usually have around.

> I wish you relief from pain :-)))



QQQte@webtv.net

2005-04-25, 10:50 pm

whoa' money indeed spells greed for the needy.

please, please correct me if i'm wrong but i read somewhere that the
cost of meds in the states are so high because we have to cover the cost
for the lower amount of money that canadian's have to pay..... is this
b.s? or have i one more time let the news take me for a spin?.... dory

........" There is so much good in the worst of us and so much bad in
the best of us that its rather hard to discern which of us ought to
reform the rest of us"...........
.........Alain Fournier.........

Michael

2005-04-26, 8:50 am

QQQte@webtv.net wrote:

> whoa' money indeed spells greed for the needy.
>
> please, please correct me if i'm wrong but i read somewhere that the
> cost of meds in the states are so high because we have to cover the
> cost for the lower amount of money that canadian's have to pay.....
> is this b.s?


It's utter BS, Dory.

For starters, GW is a British company, and Canada is the only place on earth
where it's legal for them to sell their Sativex product. The USA has
nothing whatsoever to do with it, and quite frankly, they don't *want*
anything to do with it, because releasing it for sale in the US means
admitting that the cannabis plant has medical uses, exactly the opposite of
what US law has said for decades.

The fact that Sativex has been approved in Canada is a direct slap in the
face to almost 70 years of US (and over 80 years of Canadian) lies,
persecution and government-sanctioned killing.

On top of that, the world's biggest pharmas spend the bulk of their real
money in the USA, and the bulk of their American expenditures go to pay for
advertizing, doctor-travel for seminars, and other marketing costs, for
legal and regulatory expenses, and for lobbying the Federal and State
governments to allow them to make more money and spend less.

All the talk about the US subsidizing other countries, and about the cost of
R&D pushing the price of drugs upward was debunked long ago by the
industry's own submissions to the US Congress.


> or have i one more time let the news take me for a
> spin?.... dory
>
> ......." There is so much good in the worst of us and so much bad in
> the best of us that its rather hard to discern which of us ought to
> reform the rest of us"...........
> .........Alain Fournier.........



rose

2005-04-26, 5:51 pm

bobbyD wrote:
>
> i plan to test this medication like itested the synthetic crap,,

meaning i
> will onlu use sativex and not smoke,, unless it is useless and i get

no help
> from it,,,


good luck, bob, ii'll be really interested in hearing about how it
works for you!

rose

bobbyD

2005-04-26, 10:56 pm


"Dove 1" <Yonna1@webtv.net> wrote in message
news:17475-426D8F7A-568@storefull-3355.bay.webtv.net...
> Oh bobbyD - That sounds like a good plan -- I hope it is wonderful --
> for you - and maybe later for all of us !


me too if anything my desire is to stop or cut out smoking,,


> When you mentioned synthetic "crap" -do you mean the medicine that was
> manufactured also from cannibus in a pill form ? Does it not work ?


i mean Marinol, and Nabilone / Cesamet

the reason it is crap??? it is totally man made synthetic crap,, it does
nothing for me and i gave it a good ole try too, i stopped smoking and used
only the pills,,,

the pills contained 1mg of synthetic thc,, whereas my marijuana has on
average 200-240mgs of thc in each Gram, i roll 2 joints per gram - thats
100-120mgs of pure marijuana extract in each joint of MY medicine,,,

we will see if this stuff works,, and i may be not helped at all but you
could be ,, i smoke a 1/2 ounce of marijuana everyday!!! ,, 1/2 ounce!!!

bobbyD


> I wish you relief from pain :-)))
>



bobbyD

2005-04-26, 10:56 pm


"Michael" <muirhead@haidagwaii.net> wrote in message
news:y5CdnYZKJei3NfDfRVn-og@qcislands.net...
> Dove 1 wrote:
>
>
> Apparently, it does work, but how *well* it works is still sort of a trade
> secret.
>
> It's not in a pill form, but in a spray that you squirt under your tonguue
> (or between cheek and gum)... it's absorbed there only a little slower
> than by inhaling smoke - and it's less toxic because there are no
> combustion products.
>
> That said... it's going to be damned expensive compared to even the very
> best bud on the planet. My guess (it's *only* a guess) is that it will
> be over $3 per squirt-dose (2.7/2.5mg of THC/CBD).
>
> For comparison, I get approximately the same dose of both compounds from
> about 20mg of good bud. A quarter ounce of good bud (28 grams = 1400
> "sativex-sized" doses) costs me $100 at most,


a 1/4 ouce is 7 grams,, and are you paying 100 bucks a 1/4??? or is it 100
an ounce??? let me know eh???


which means I pay 7/10 of a
> cent per dose (actually a *very* tiny dose: I usually smoke about 3 to 5
> times that much at once, and I know Bob sometimes smokes the equivalent of
> more than 100 "standard" Sativex doses at a go.)


basically i measure my usage by the amount of Zig Zag packs i empty, per
week!!!!

but i keep myself flooded with marijuana and i feel fantastic,,, well
fantasticker than my un-normal self.

i smoke more pot than most pot smokers can handle,,,

i f i get a small bit of relieff from this sativex spray, i will be happy
and i know it would benefit most of you better,, as i am so used to massive
doses of marijuana when i stop and i compensate with sprayed marijuana i
might not get the same amount of marijuana per day,, and i might feel that
loss of medication intake,, thats how i can measure if it works,, to go
without anything but the spray,, and see if it helps by itself,,,


>
> If I pay 0.7 cents per "standard dose" and Sativex is going to cost $3 for
> the same dose... that would make the cost of Sativex more than 420 times
> the cost of the bud I usually have around.
>
>
>


good info
bob


bobbyD

2005-04-26, 10:56 pm


"rose" <rosedawn_scott@yahoo.com> wrote in message
news:1114535393.662667.189890@o13g2000cwo.googlegroups.com...
> bobbyD wrote:
> meaning i
> no help
>
> good luck, bob, ii'll be really interested in hearing about how it
> works for you!
>
> rose
>


i will keep you all informed,, i hope it has some efficacy,, but so far it
seems the dose will be alot lower than what i need in my experience to
obtain medical symptom relief,,,to any extent.

on the side,, i am also testing my new strains i have,, , 8 strains ready,
to test,, one i think will measure in the high 26-29% thc range,,

i also have a new hydrophonic method that is guaranteed to grow 30% thc
marijuana,, i am testing too,,,, it all has to do with heat temperature of
the water,, keeping it at one temp and never letting it fluctuate,, plus
some root airation,,, that allows you to grow plant in the air,, no soil no
water,,, misted sprays into hanging open roots,, -airophonics its called,,
so i keep busy these days,,

bobbyD


Michael

2005-04-26, 10:56 pm

bobbyD wrote:

> "Michael" <muirhead@haidagwaii.net> wrote in message
> news:y5CdnYZKJei3NfDfRVn-og@qcislands.net...
>
> a 1/4 ouce is 7 grams,, and are you paying 100 bucks a 1/4??? or is
> it 100 an ounce??? let me know eh???
>
>
> which means I pay 7/10 of a
>
> basically i measure my usage by the amount of Zig Zag packs i empty,
> per week!!!!
>
> but i keep myself flooded with marijuana and i feel fantastic,,, well
> fantasticker than my un-normal self.
>
> i smoke more pot than most pot smokers can handle,,,
>
> i f i get a small bit of relieff from this sativex spray, i will be
> happy and i know it would benefit most of you better,, as i am so
> used to massive doses of marijuana when i stop and i compensate with
> sprayed marijuana i might not get the same amount of marijuana per
> day,, and i might feel that loss of medication intake,, thats how i
> can measure if it works,, to go without anything but the spray,, and
> see if it helps by itself,,,
>
>
> good info
> bob



Michael

2005-04-26, 10:56 pm

Oooops.... premature emission...

bobbyD wrote:

> "Michael" <muirhead@haidagwaii.net> wrote in message
> news:y5CdnYZKJei3NfDfRVn-og@qcislands.net...


>
> a 1/4 ouce is 7 grams,, and are you paying 100 bucks a 1/4??? or is
> it 100 an ounce??? let me know eh???


That's at the very *most*, Bob.

I use so little pot that it's rarely necessary for me to buy more than an
eighth at a time, and that lasts for several weeks. A quarter of most bud
runs about $70-85 around here, but stuff like this
http://qcislands.ca/muirhead/PurtyBud.jpg
can cost $50 for an eighth.



> which means I pay 7/10 of a
>
> basically i measure my usage by the amount of Zig Zag packs i empty,
> per week!!!!


That's kind of how I figgered it. I know you smoke a great deal to manage
pain... I smoke only a little bit to manage spaticity and spasm.


> but i keep myself flooded with marijuana and i feel fantastic,,, well
> fantasticker than my un-normal self.
>
> i smoke more pot than most pot smokers can handle,,,


I could *handle* it... I just couldn't feed or walk my friggin' *dog* after
smoking like that! :-))))


> i f i get a small bit of relieff from this sativex spray, i will be
> happy and i know it would benefit most of you better,,


I'm guessing that it'll be a little (not much) more effective than either
Cesamet (synthetic cannabidiol) or Marinol (synthetic THC) alone... but I'm
also guessing that you'll find the 6-sprays-a-day dosage limit doesn't do
very much for pain alone. If the pain were neurogenic or due to muscle
spasm, it might help more, but my gut feeling is that if you use THC/CBD to
do what morphine does, you'll need a lot of it.

> as i am so
> used to massive doses of marijuana when i stop and i compensate with
> sprayed marijuana i might not get the same amount of marijuana per
> day,, and i might feel that loss of medication intake,, thats how i
> can measure if it works,, to go without anything but the spray,, and
> see if it helps by itself,,,


It'll probably help. It'll probably help very little in comparison to
your regular smoke, though. :-(

I know you're involved in some cannabis resin/oil based med development
work, and if this is the route you'd like to try for your meds (it beats
smoking, at least most of the time) you oughta work on an oral-absorption
thing like this, but in a much greater strength... for instance, say, 50/50
THC/CBD and total dose of 25mg per spray.

2 to 4 sprays of something like that (q2h or q3h) would probably do you just
fine, wouldn't it?

>
> good info
> bob



rose

2005-04-29, 11:52 am

bobbyD wrote:
> i will keep you all informed,, i hope it has some efficacy,, but so

far it
> seems the dose will be alot lower than what i need in my experience

to
> obtain medical symptom relief,,,to any extent.


hey bob, have you got the rx yet? does it have ingredient percentages,
like how much THC, CBD on the label? and i'm really curious about the
dosage instructions as well -- how do they say a person SHOULD be using
sativex?

> i also have a new hydrophonic method that is guaranteed to grow 30%

thc
> marijuana,, i am testing too,,,, it all has to do with heat

temperature of
> the water,, keeping it at one temp and never letting it fluctuate,,

plus
> some root airation,,, that allows you to grow plant in the air,, no

soil no
> water,,, misted sprays into hanging open roots,, -airophonics its

called,,
> so i keep busy these days,,


airoponics, that's a new one on me, it sounds great if it works!

hey bob, i have a question about hydro-stuff. i've always been an
outside gardener, the plants love our climate, during grow season we've
got a natural 12/12 sunlight/dark cycle, the stalks get really strong,
like tree branches almost, and i grow them in pots to keep them short
and bushy, rather than tall and spindly -- i've had really good fortune
growing this way, and it's definitely my pref. now that we've got our
back fence rebuilt, the yard is very private, great place for growing.
i'd continue doing it that way, EXCEPT, the new local medpot regs say
that i have to grow inside, which is new to me.

shortly after prop 215 passed, back in the mid 90s, i tried growing in
a closet, but my closets are just so TINY that all i could fit in there
was one fan, one light, and two plants. been trying to think of where i
could kind of cordon off an area and make an indoor gardening area. but
another thing i wonder about is cost -- both 'can i afford it?' and
also, a year or so ago, we hard about DEA 'hydro-raids' on private
homes wher epeople were suspected of growing weed because their G&E
bills seemed to reflect it. one individual who was picked up in the
raid had a home greenhouse -- i mean all LEGAL plants, it just cost him
a lot to keep them growing. so they let this dude go. but, if that's
how they're trying to find people who are growing pot, and it's the
feds and not the locals who show up -- they're not going to honor or
care about my medical exemption, i don't think. i've got a good
relationship with the local sheriffs, i've got NO relationship with the
DEA, and i'd like to keep it that way!!!

i think the aeroponics sounds FASCINATING, but i wonder -- would it
entail giving the feds ammo to come bust me in the form of a gas and
electric bill that indicates i'm running a 'grow-op' -- ???? i'm
permitted up to 24 plants, but never grow that many, probably more like
10 at a time at MOST.

it's the season and i haven't planted anything yet, cuz i'm still
trying to figure out the best way to go about it.

rose

bobbyD

2005-04-29, 5:51 pm


"rose" <rosedawn_scott@yahoo.com> wrote in message
news:1114790139.998880.83560@f14g2000cwb.googlegroups.com...
> bobbyD wrote:
> far it
> to
>
> hey bob, have you got the rx yet? does it have ingredient percentages,
> like how much THC, CBD on the label? and i'm really curious about the
> dosage instructions as well -- how do they say a person SHOULD be using
> sativex?


my pharmacist is waiting for her supplier to get back to her,, i got the
runaround from Bayer,, they just regurgitated the news release,,

late spring is all they will say,, maybe 2-3 weeks or so,,,

michael did some math and it looks like ;

my dose is start at 3 sprays per day ..

move up to 6 sprays max per day

michael syas it might have in the 6 total spray the same amount of thc etc
as in 1g of smoked pot,, at 15-16 % thc levels,,,

so i wait for the drug to get to my pharmacy so i can try it.

bobbyD


>
> thc
> temperature of
> plus
> soil no
> called,,
>
> airoponics, that's a new one on me, it sounds great if it works!
>
> hey bob, i have a question about hydro-stuff. i've always been an
> outside gardener, the plants love our climate, during grow season we've
> got a natural 12/12 sunlight/dark cycle, the stalks get really strong,
> like tree branches almost, and i grow them in pots to keep them short
> and bushy, rather than tall and spindly -- i've had really good fortune
> growing this way, and it's definitely my pref. now that we've got our
> back fence rebuilt, the yard is very private, great place for growing.
> i'd continue doing it that way, EXCEPT, the new local medpot regs say
> that i have to grow inside, which is new to me.
>
> shortly after prop 215 passed, back in the mid 90s, i tried growing in
> a closet, but my closets are just so TINY that all i could fit in there
> was one fan, one light, and two plants. been trying to think of where i
> could kind of cordon off an area and make an indoor gardening area. but
> another thing i wonder about is cost -- both 'can i afford it?' and
> also, a year or so ago, we hard about DEA 'hydro-raids' on private
> homes wher epeople were suspected of growing weed because their G&E
> bills seemed to reflect it. one individual who was picked up in the
> raid had a home greenhouse -- i mean all LEGAL plants, it just cost him
> a lot to keep them growing. so they let this dude go. but, if that's
> how they're trying to find people who are growing pot, and it's the
> feds and not the locals who show up -- they're not going to honor or
> care about my medical exemption, i don't think. i've got a good
> relationship with the local sheriffs, i've got NO relationship with the
> DEA, and i'd like to keep it that way!!!
>
> i think the aeroponics sounds FASCINATING, but i wonder -- would it
> entail giving the feds ammo to come bust me in the form of a gas and
> electric bill that indicates i'm running a 'grow-op' -- ???? i'm
> permitted up to 24 plants, but never grow that many, probably more like
> 10 at a time at MOST.
>
> it's the season and i haven't planted anything yet, cuz i'm still
> trying to figure out the best way to go about it.
>
> rose
>



Fred

2005-04-29, 5:51 pm

"bobbyD" <phatbhatREMOVE@telus.net> wrote in
news:6_vce.12645$tg1.895@edtnps84:
[vbcol=seagreen]
>
> "rose" <rosedawn_scott@yahoo.com> wrote in message
> news:1114790139.998880.83560@f14g2000cwb.googlegroups.com...
>
> my pharmacist is waiting for her supplier to get back to her,, i got
> the runaround from Bayer,, they just regurgitated the news release,,
>
> late spring is all they will say,, maybe 2-3 weeks or so,,,
>
> michael did some math and it looks like ;
>
> my dose is start at 3 sprays per day ..
>
> move up to 6 sprays max per day
>
> michael syas it might have in the 6 total spray the same amount of thc
> etc as in 1g of smoked pot,, at 15-16 % thc levels,,,
>
> so i wait for the drug to get to my pharmacy so i can try it.
>
> bobbyD
>
>

Are you talking about the US or Canada? I would like to get a Sativex Rx if
I can. I recently started smoking again after 2+ years. It really helps my
symptoms. We moved and getting something at the new location was difficult
to say the least. Smoking is inconvenient. I haven't smoked in over a week.
My MS symptoms are coming back with a vengance. After "administration" my
legs would not shake at all. That benefit would last 48 hours. Now I have
really bad spasms in them. I do not see the possibility to smoke until at
least next week. My girlfriend's Mother is visiting until next week and
doing anything around her is not a good idea. I have no problem with
smoking. In college they thought I was going to join a reggae band. Now it
would be more convenient to use a spray.

Fred.
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