Psoriasis support - palmoplantar keratoderma

Author

palmoplantar keratoderma

krystalgal5

2006-08-07, 8:24 am

Hi
My three year old daughter was recently diagnosed with a rare skin
condition called palmoplantar keratodrema.
It is a condition where the palm of her hands and the soles of her feet
are thicker and extremly dry.
It is a hereditary condition, the unusual part is both her father and
myself don't have and can't find a link to where it has come from.
If anyone has the same condition or knows somone who has it PLEASE
contact me..

kristie13810@hotmail.com
If anyone can help please do..
thanks.

randall

2006-08-07, 4:27 pm

Hi Kristie,

I don't have it and I doubt anyone in the group right now does.

Did you run the pubmed on it?

http://www.ncbi.nlm.nih.gov/entrez/...keratoderma+ppk

#10 in that bunch may be an option. Treatment with 5-FU. You could
run it past your doctor for grins.

http://www.ncbi.nlm.nih.gov/entrez/...l=pubmed_docsum
Treatment of palmoplantar keratoderma with continuous infusion
5-fluorouracil.

* Lienemann AO,
* Colucci VJ,
* Jones MS,
* Trauscht JM.

Franciscan Health System, Tacoma, Washington, USA.

A 49-year-old man electively chose to undergo a trial of intravenous
chemotherapy with 5-fluorouracil (5-FU) for his inherited punctate
palmoplantar keratoderma (PPK). His father also had this skin disorder,
which coincidentally cleared after 2 courses of chemotherapy consisting
of 5-FU and cisplatin to treat his lung cancer, prompting the patient
to undergo this trial of therapy. After the patient's first course of a
5-day continuous infusion (CI) of 5-FU (1000 mg/m2 per day), the
lesions on his hands and feet regressed by approximately 80%. However,
after completion of each course, the lesions seemed to reappear to some
degree. The patient desired to pursue further therapy; therefore, CI
5-FU at a dose of 250 mg/m2 per day (500 mg/d) was instituted, while
pyridoxine was avoided in the hope of causing a hand-foot syndrome that
may provide some long-term benefit. After receiving a 12-week course of
therapy of CI 5-FU at 250 mg/m2 per day, his lesions were approximately
95% improved, with only a few minute punctate keratoses remaining. At
follow-up nearly 4 years later, the lesions remain 90% cleared.

PMID: 15186044

Search the psoriasis newsgroup for more 5-Fu treatments.

Or search all groups for P and 5-fu,
http://groups.google.com/groups/sea...sis&qt_s=Search

Good luck,

let us know how you do.

randall...

krystalgal5 wrote:
> Hi
> My three year old daughter was recently diagnosed with a rare skin
> condition called palmoplantar keratodrema.
> It is a condition where the palm of her hands and the soles of her feet
> are thicker and extremly dry.
> It is a hereditary condition, the unusual part is both her father and
> myself don't have and can't find a link to where it has come from.
> If anyone has the same condition or knows somone who has it PLEASE
> contact me..
>
> kristie13810@hotmail.com
> If anyone can help please do..
> thanks.

JXStern

2006-08-07, 4:27 pm

On 7 Aug 2006 02:28:17 -0700, "krystalgal5" <kristie13810@hotmail.com>
wrote:
>My three year old daughter was recently diagnosed with a rare skin
>condition called palmoplantar keratodrema.
>It is a condition where the palm of her hands and the soles of her feet
>are thicker and extremly dry.
>It is a hereditary condition, the unusual part is both her father and
>myself don't have and can't find a link to where it has come from.
>If anyone has the same condition or knows somone who has it PLEASE
>contact me..

I once shook hands with a guy who had what I'm guessing was that, he
just assured me it was not contagious, ... and I assured him the same
for my psoriasis!

Sorry, that's all I know about it, except he seemed otherwise fine.

J.

giurgiu

2006-08-08, 8:24 am

krystalgal5 wrote:
> Hi
> My three year old daughter was recently diagnosed with a rare skin
> condition called palmoplantar keratodrema.
> It is a condition where the palm of her hands and the soles of her feet
> are thicker and extremly dry.
> It is a hereditary condition, the unusual part is both her father and
> myself don't have and can't find a link to where it has come from.
> If anyone has the same condition or knows somone who has it PLEASE
> contact me..

Hey there, If you want to find out more about these skin problems and
even try a new treatment without ointments or diet only with plants
visit: WWW.deniplant.ro the english version.. my advice is to stop
using ointments for your daughter cause she is still a baby and they
only develop more this disease...

giurgiu

2006-08-08, 8:24 am

Hey i see you have psoriasis aren't you sick of ointments and other
drugs that just heal momentarilly the skin surface and not the intern
causes so this disease appears again..and again even more powerfull?

DENIPLANT leader in psoriasis...a therapy with plants without ointments
or diet.
Deniplant is a new discovery in medicine because treates the intern
causes that produce and develop psoriasis and other skin diseases. for
more detailes please visit :

http://www.deniplant.ro (the english version)
or http://www.psoriazis-deniplant.ro

JXStern

2006-08-08, 4:28 pm

On 8 Aug 2006 04:04:04 -0700, "giurgiu" <giurgiu@deniplant.ro> wrote:
>Hey i see you have psoriasis aren't you sick of ointments and other
>drugs that just heal momentarilly the skin surface and not the intern
>causes so this disease appears again..and again even more powerfull?
>
>
>DENIPLANT leader in psoriasis...a therapy with plants without ointments
>or diet.
>Deniplant is a new discovery in medicine because treates the intern
>causes that produce and develop psoriasis and other skin diseases. for
>more detailes please visit :

Good idea, I've never seen a plant with psoriasis!

J.

Shooting Star

2006-08-20, 4:25 pm

I think it is one of the symptoms of reactive arthritis. I was diagnosed
with that around 20 years ago. I had in on the soles of my feet. There was
nothing that could be done about it though. It disappeared after 6 months
without any treatment. It looked horrible (much like this
http://162.129.70.33/images/Palmopl...ma_1_040130.jpg)

Susan

2006-08-20, 4:25 pm

x-no-archive: yes

Shooting Star wrote:
> I think it is one of the symptoms of reactive arthritis. I was diagnosed
> with that around 20 years ago. I had in on the soles of my feet. There was
> nothing that could be done about it though. It disappeared after 6 months
> without any treatment. It looked horrible (much like this
> http://162.129.70.33/images/Palmopl...ma_1_040130.jpg)
>
>

There *is* something to be done about it, though. Antibiotics,
specifically, doxycycline, double the daily dose in my case.

Susan