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Home > Archive > Psoriasis support > June 2006 > You might want to try this out! Eat Pancreatic enzymes and use Lamisil!
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You might want to try this out! Eat Pancreatic enzymes and use Lamisil!
|
|
| Benjamin Blavat 2006-06-04, 9:15 am |
| Hi,
In trying to find a cure for what causes Psoriasis. I believe I am now
closer than ever. I still believe its has a fungal component, but the
mechanism locking us from clearing turns out I believe, is not enough bile
being delivered to digest the food we eat by ourselves! Overtime other
things have found out about the feast of unclaimed food in our gut. An easy
proof of this is to eat, enzymes to recreate the output of your pancreas.
Within days you should see clearing start to occur, I did, you can hasten
this process with Lamisil AT or any topical OTC or prescription antifungal.
A more permanent solution is to clear the stones and sand that block our
bile ducts in our liver and gall bladders. I have passed one stone in my
life. I had some in my saliva gland, so can believe the hypothesis of more
in my liver and gall bladder. A method to clearing, is an apple juice fast
with a EVO and lime juice purge at the end! Do a Google search on "Liver
Cleansing".
I am only at the testing stage myself, but the results are so wonderful and
the cost so little I felt I should share my good fortune. I should add other
symptoms have faded for me and my wife (who doesn't have Psoriasis but
Fibromyalga/IBS). GL,
BTW, I just applied what someone else found effective for eczema to my
Psoriasis.
--
With good thoughts,
Benjamin Blavat
| |
| randall 2006-06-04, 9:15 am |
|
Benjamin Blavat wrote:
> Hi,
>
> In trying to find a cure for what causes Psoriasis. I believe I am now
> closer than ever.
Congrats!
> I still believe its has a fungal component, but the
> mechanism locking us from clearing turns out I believe, is not enough bile
> being delivered to digest the food we eat by ourselves! Overtime other
> things have found out about the feast of unclaimed food in our gut. An easy
> proof of this is to eat, enzymes to recreate the output of your pancreas.
> Within days you should see clearing start to occur, I did, you can hasten
> this process with Lamisil AT or any topical OTC or prescription antifungal.
I was happy with N-zimes more then a few times,
http://www.nzimes.com/
I took them in conjunction with the wit kit implant and proflora
program.
>
> A more permanent solution is to clear the stones and sand that block our
> bile ducts in our liver and gall bladders. I have passed one stone in my
> life. I had some in my saliva gland, so can believe the hypothesis of more
> in my liver and gall bladder. A method to clearing, is an apple juice fast
> with a EVO and lime juice purge at the end! Do a Google search on "Liver
> Cleansing".
Never tried the evoo purge. Something to look forward to. <g>
>
> I am only at the testing stage myself, but the results are so wonderful and
> the cost so little I felt I should share my good fortune. I should add other
> symptoms have faded for me and my wife (who doesn't have Psoriasis but
> Fibromyalga/IBS). GL,
If fat digestion is and it is, a psoriasis problem, then it's no wonder
that a highly vegetarian diet helps to correct that problem.
http://www.enzymesinc.com/supplemen...me-therapy.html
[...]
According to Dr. Howell's research, _natural_ or supplemental food
enzymes can digest 75% of your food before the lower stomach's
digestive juices are even activated.
By taking advantage of these food enzymes, we increase the nutritional
value of our meals and avoid several of the digestive difficulties so
many of us experience, such as bloating, indigestion, heartburn,
fullness and gas.
Coincidentally, also in 1932 Dr. Francis Pottenger began a ten year
study that showed cats fed raw food diets maintained health and vigor
whereas, cats consuming cooked diets exhibited evidence of degenerative
disease. Pottenger's data supported Howell's theories that raw food
contains a vital factor no longer present in cooked food... ENZYMES!
---------------------------------------------------------------------------
>
> BTW, I just applied what someone else found effective for eczema to my
> Psoriasis.
I remember that page, why didn't you post it?
randall...
> --
> With good thoughts,
> Benjamin Blavat
| |
| Benjamin Blavat 2006-06-04, 9:15 am |
| Hi Randall,
I sent you the URL, several weeks ago, http://www.eczemacure.info. It's so
simple, it would be a shame, if more folks didn't get a chance to see it.
Ben
"randall" <ranhub11@aol.com> wrote in message
news:1148353210.048447.182910@i39g2000cwa.googlegroups.com...
>
> Benjamin Blavat wrote:
>
> Congrats!
>
>
>
> I was happy with N-zimes more then a few times,
> http://www.nzimes.com/
>
> I took them in conjunction with the wit kit implant and proflora
> program.
>
>
> Never tried the evoo purge. Something to look forward to. <g>
>
> If fat digestion is and it is, a psoriasis problem, then it's no wonder
> that a highly vegetarian diet helps to correct that problem.
>
> http://www.enzymesinc.com/supplemen...me-therapy.html
> [...]
>
> According to Dr. Howell's research, _natural_ or supplemental food
> enzymes can digest 75% of your food before the lower stomach's
> digestive juices are even activated.
>
> By taking advantage of these food enzymes, we increase the nutritional
> value of our meals and avoid several of the digestive difficulties so
> many of us experience, such as bloating, indigestion, heartburn,
> fullness and gas.
>
> Coincidentally, also in 1932 Dr. Francis Pottenger began a ten year
> study that showed cats fed raw food diets maintained health and vigor
> whereas, cats consuming cooked diets exhibited evidence of degenerative
> disease. Pottenger's data supported Howell's theories that raw food
> contains a vital factor no longer present in cooked food... ENZYMES!
>
> ---------------------------------------------------------------------------
>
> I remember that page, why didn't you post it?
>
> randall...
>
>
>
| |
| Cruiser 2006-06-04, 9:15 am |
| Ben,
This is an interesting idea, that seems to make sense in some ways.
P sufferers may not get enough B12 because of digestive problems. It is
possible that other nutrients are also not being absorbed due to lack of
digestion. Uwe says we do not get enough of his secret nutrients from diet.
Maybe we *can* get enough, with improved digestion. It could be that we do
not have to figure out what he is supplementing.
With improved digestion, you could be short circuiting Uwe's "cure" by
getting from food, what he is supplmenting because of digestive problems.
It might be a good idea to avoid, stress, alcohol, tobacco, and caffeine,
while trying the pancreatic enzymes.
Cruiser
"Benjamin Blavat" <ben14@adelphia.net> wrote in message
news:3PqdnY_JwONr6e_ZRVn-jQ@adelphia.com...
> Hi,
>
> In trying to find a cure for what causes Psoriasis. I believe I am now
> closer than ever. I still believe its has a fungal component, but the
> mechanism locking us from clearing turns out I believe, is not enough bile
> being delivered to digest the food we eat by ourselves! Overtime other
> things have found out about the feast of unclaimed food in our gut. An
easy
> proof of this is to eat, enzymes to recreate the output of your pancreas.
> Within days you should see clearing start to occur, I did, you can hasten
> this process with Lamisil AT or any topical OTC or prescription
antifungal.
>
> A more permanent solution is to clear the stones and sand that block our
> bile ducts in our liver and gall bladders. I have passed one stone in my
> life. I had some in my saliva gland, so can believe the hypothesis of more
> in my liver and gall bladder. A method to clearing, is an apple juice
fast
> with a EVO and lime juice purge at the end! Do a Google search on "Liver
> Cleansing".
>
> I am only at the testing stage myself, but the results are so wonderful
and
> the cost so little I felt I should share my good fortune. I should add
other
> symptoms have faded for me and my wife (who doesn't have Psoriasis but
> Fibromyalga/IBS). GL,
>
> BTW, I just applied what someone else found effective for eczema to my
> Psoriasis.
> --
> With good thoughts,
> Benjamin Blavat
>
>
| |
| Cruiser 2006-06-04, 9:15 am |
| O.K.
I bit on this one.
I have picked up some digestive enzymes to try out.
I got the Natural Factors full spectrum, high potency digestive enzymes.
I just took two with my turkey submarine and V8 juice.
Cruiser
| |
|
| I take two tablets before and after I eat. I don't know which is more
effective so I am doing the double dose. Not much danger of over
enzyming! The real solution will be the fast/cleansing, I imagine
without changing diet it will be required regularly for life.
I am continuing to feel and look better daily, the clearing is slow but
continous. Today I was able to take the cavitron at the dentist, for
the first time ever, so my teeth are much less sensitive now, than
before the new supplement. Hair is still returning and turning darker,
not bad from a 6 inch bald spot and white hair to now light hair
throughout the baldspot (in the front too)!
All Psoriasis areas that weren't controlled by the antifungals ARE
responding to the enzymes. I have some red spots left but no more
plaques! I must be down to 1% or less now. I still take the
prsecription antifungals but less of them now with no change in relief!
All twenty nails are nearing normal thickness lie flat and aren't
painful anymore.
My parathesis, inappropriate feeling response in my thighs, is gone on
the left side and greatly diminished on the right. Cysts that I had for
20+ years through my groin, thigh and anal areas are gone or nearly so.
Btw all arthritis is gone and the calcium deposits on my knuckels are
gone too. I now have great clarity of mind, which had been missing for
a time! These are my initial impressions of taking the enzymes. I had
similar success the other times I took enzmes too, but didn't realize
it was the enzymes at that time. Please update me on your results, I am
very excited by what I am seeing and hope the same for everyone. GL,
| |
| randall 2006-06-04, 9:15 am |
| OK BEN,
FESS Up!
Your taking Uwe's secret formula!?!?
If not it sure sounds like it.
If truly not, then congrats, your a true wonder man!
The insipirations around here are astounding.
ben wrote:
> I take two tablets before and after I eat. I don't know which is more
> effective so I am doing the double dose. Not much danger of over
> enzyming! The real solution will be the fast/cleansing, I imagine
> without changing diet it will be required regularly for life.
Like what do you figure? Once a week, bi-weekly, monthly?
One, two or more days at a time?
>
> I am continuing to feel and look better daily, the clearing is slow but
> continous. Today I was able to take the cavitron at the dentist, for
> the first time ever, so my teeth are much less sensitive now, than
> before the new supplement.
Your saying the new suPPlement are the enzymes? Which brand?
> Hair is still returning and turning darker,
> not bad from a 6 inch bald spot and white hair to now light hair
> throughout the baldspot (in the front too)!
Wow wow wow. So what does your sweet heart say?
>
> All Psoriasis areas that weren't controlled by the antifungals ARE
> responding to the enzymes. I have some red spots left but no more
> plaques! I must be down to 1% or less now.
How large where your plaques at the most recent time period when
they were at least 6% pasi or more? Or should i say thickness etc.
> I still take the
> prsecription antifungals but less of them now with no change in relief!
> All twenty nails are nearing normal thickness lie flat and aren't
> painful anymore.
Wow.
>
> My parathesis, inappropriate feeling response in my thighs, is gone on
> the left side and greatly diminished on the right. Cysts that I had for
> 20+ years through my groin, thigh and anal areas are gone or nearly so.
wow..
>
>
> Btw all arthritis is gone and the calcium deposits on my knuckels are
> gone too. I now have great clarity of mind, which had been missing for
> a time! These are my initial impressions of taking the enzymes. I had
> similar success the other times I took enzmes too, but didn't realize
> it was the enzymes at that time. Please update me on your results, I am
> very excited by what I am seeing and hope the same for everyone. GL,
I hope a bunch of folks verify this.
Btw- how did you liver enzymes look before and after? I would think
that some folks with high alt/ast may need to be quite cautious prior
to embarking on this head strong.
Don't pull a paul bragg on us now. He felt so good he accidentally
died.
But he felt great no doubt when he meet his fate,
http://www.evolutionhealth.com/brag...le_fasting.html
randall...
| |
| Benjamin Blavat 2006-06-04, 9:15 am |
| Hey Randall,
No, don't have the Uwe formulation. Its just the evolution of my search system. Most research into Psoriasis follows the make up of the
plaques. I have been looking at the what (as in what causes it)! Psoriasis, seems to be for me, an undiagnosed Tinea infection, mine reacts to antifungal regimens, but they ultimately fail. So I looked for a locking mechanism. I thought it was Candida for many years. but my father's recent clearing in the hospital, was on top of a horrible case of Candida! So I looked for what else could be causing the failure of my immune system. that pointed to the liver and gallbladder, a failure of the bile system, its a good fit, now the question morphs to what causes the stones to form. If you read the website http://www.eczemacure.info That is where the witches fail for me. Their explanation as to why it works.
I am trying another brand of enzyme (2 for 1 Super Enzymes, Vitaminworld) right now while, waiting to get the "Pancreatin" from Vitaminworld, the Pancreatin seems to work better and is cheaper! Solgar " Pancreatin" is the brand from Edwin's website.
It seems so obvious to look at digestion as the cause of Psoriasis, but I could never put the tail on the donkey. This search should be right up your very talented alley. Find the causes of stones forming and accumulating, this should be the bottom line on our long term return to robust health. This is a real hard condition that could be the cause of the many different symptoms described throughout medicine without known cause.
We need data on what causes sand and stones to form and accumulate. From reading Edwin website, it seems clear to me that he is making new stones every month. So I figure bimonthly flushing to avoid any chance of non or low delivery of bile. It would seem to me that the makeup of bile would adapt over time to supply the exactly right enzymes you require for any diet available, making it preferable to taking the supplements for a long time, I believe with supplements there would be holes in your enzymes supply.
The supplements are the test that shows the need to cleanse the liver and gallbladder.
--
With good thoughts,
Benjamin Blavat
"randall" <ranhub11@aol.com> wrote in message news:1148509143.445849.223090@i39g2000cwa.googlegroups.com...
> OK BEN,
>
>
> FESS Up!
>
> Your taking Uwe's secret formula!?!?
>
> If not it sure sounds like it.
>
>
> If truly not, then congrats, your a true wonder man!
>
> The insipirations around here are astounding.
>
>
>
> ben wrote:
>
> Like what do you figure? Once a week, bi-weekly, monthly?
> One, two or more days at a time?
>
>
> Your saying the new suPPlement are the enzymes? Which brand?
>
>
> Wow wow wow. So what does your sweet heart say?
>
>
>
> How large where your plaques at the most recent time period when
> they were at least 6% pasi or more? Or should i say thickness etc.
>
>
>
> Wow.
>
>
> wow..
>
>
> I hope a bunch of folks verify this.
>
> Btw- how did you liver enzymes look before and after? I would think
> that some folks with high alt/ast may need to be quite cautious prior
> to embarking on this head strong.
>
> Don't pull a paul bragg on us now. He felt so good he accidentally
> died.
> But he felt great no doubt when he meet his fate,
> http://www.evolutionhealth.com/brag...le_fasting.html
>
> randall...
>
| |
|
| Just curious, but have you ever had an ultra-sound of your liver and
gallbladder done? It is one of several tests that will show stones
(particularly large stones like the one shown on the site you linked to) and
provide valuable info towards proving or disproving your theory regarding
blocked bile ducts.
mfl
| |
| randall 2006-06-04, 9:15 am |
|
Benjamin Blavat wrote:
> Hey Randall,
>
> No, don't have the Uwe formulation.
Unless you know his secret, how would you know? You may
be taking it. How else does one grow new hair and have a
rock hard insurection? lol
> Its just the evolution of my search system.
I know that's been a long odyssey. My own homeric epic washed
me up to the shores of thewholewhey.com and after six years i'm still
very happy with it. Not that i haven't gone forward with
supplements to booster individual areas that tweak my
YMMV areas.
OTOH, I think my mom had gsd during one of her pregnancies
http://www.parismuse.com/moxiepix/b3_66.jpg
I wonder if it was me? I'll ask. But the P came from
paternal genes in my family and prior to my dad we
don't know who had it or where that gene PoP'ed uP!
Maybe there was an Ashkenazi Jew in the woodshed in days of yore?
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=12941092
> Most research into Psoriasis follows the make up of the
> plaques. I have been looking at the what
> (as in what causes it)! Psoriasis, seems to be for me,
> an undiagnosed Tinea infection, mine reacts to antifungal
> regimens, but they ultimately fail. So I looked for a locking
> mechanism. I thought it was Candida for many years.
> But my father's recent clearing in the hospital, was on top
> of a horrible case of Candida! So I looked for what else could
> be causing the failure of my immune system. that pointed
> to the liver and gallbladder, a failure of the bile system,
> its a good fit, now the question morphs to what causes
> the stones to form. If you read the website
http://www.eczemacure.info
> That is where the witches fail for me.
> Their explanation as to why it works.
>
> I am trying another brand of enzyme (2 for 1 Super Enzymes,
> Vitaminworld) right now while, waiting to get the
> "Pancreatin" from Vitaminworld, the Pancreatin seems
> to work better and is cheaper! Solgar " Pancreatin" is the
> brand from Edwin's website.
>
>
> It seems so obvious to look at digestion as the
> cause of Psoriasis, but I could never put the tail
> on the donkey.
> This search should be right up your very talented alley.
A few things come to mind right off the bat. Look below.
> Find the causes of stones forming and accumulating,
> this should be the bottom line on our long term return
> to robust health. This is a real hard condition that could
> be the cause of the many different symptoms described
> throughout medicine without known cause.
> We need data on what causes sand and stones to form
> and accumulate. From reading Edwin website, it seems
> clear to me that he is making new stones every month.
> So I figure bimonthly flushing to avoid any chance of non
> or low delivery of bile. It would seem to me that the makeup
> of bile would adapt over time to supply the exactly right
> enzymes you require for any diet available, making it
> preferable to taking the supplements for a long time,
> I believe with supplements there would be holes in
> your enzymes supply.
>
> The supplements are the test that shows the need to
> cleanse the liver and gallbladder.
Lets open the funky can of worms again.
http://groups.google.com/groups/sea...ria&qt_s=Search
OR
http://www.ncbi.nlm.nih.gov/entrez/...stones+etiology
GSD is not the cause of P, we can rest assured, unless there's some
connection
between the two and a similar pathogenesis. But thats still not known.
Let's play around with pubmed.
Aha!
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=16597602
Mice with stiffies! Now, this is a uwe pathway!
Whenever this comes uP, <w> i can't help but think
of that gangster. Let me find him,
http://www.americanmafia.com/Feature_Articles_181.html
[...]
Rubirosa was the ultimate pleasure seeker who loved the elegant life.
Most nights would be spent dining on exotic foods and then drinking and
dancing the rest of the evening away to the Latin rhythms that were
then so popular with the international set then.
"He also suffered," said a friend, "from a rare disease called
priapism which kept him in an almost constant state of sexual arousal
and left him unable to be sexually satisfied. He rarely achieved
orgasms during sex and then only after hours of struggle. He knew that
thing of his was his potential meal ticket and he actually trained to
keep it in peak condition. He did exercises for it. He would drink each
day a potion called pago-palo which he said came from the bark of a
certain tree in the Dominican Republic, he believed that it guaranteed
performance ... I once saw him balance a chair with a telephone book on
it atop his erection. He said to me, "It's a muscle like any other, it
can be strengthened."
<sniP>
With those presidential cites, we'd be lax to not mention that
President
Clinton has Peyronie's Disease. Was it something he ate? lol
Being raised in HOT sPrings could hold a clue to a water borne
pathogen? ;-)
http://www.goaskalice.columbia.edu/1133.html
Sorry, couldn't help it. lol
You know how I think. The next step is tyPically easy.
http://www.ncbi.nlm.nih.gov/entrez/...+etiology+flora
The first hit looks good to me.
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=16299351
Bile salt biotransformations by human intestinal bacteria.
Ridlon JM, Kang DJ, Hylemon PB.
Department of Microbiology/Immunology, Medical college of Virginia,
Virginia Commonwealth University, Richmond, VA.
Secondary bile acids, produced solely by intestinal bacteria, can
accumulate to high levels in the enterohepatic circulation of some
individuals and may contribute to the pathogenesis of colon cancer,
gallstones, and other gastrointestinal (GI) diseases. Bile salt
hydrolysis and hydroxy group dehydrogenation reactions are carried out
by a broad spectrum of intestinal anaerobic bacteria, whereas bile acid
7-dehydroxylation appears restricted to a limited number of intestinal
anaerobes representing a small fraction of the total colonic flora.
Microbial enzymes modifying bile salts differ between species with
respect to pH optima, enzyme kinetics, substrate specificity, cellular
location, and possibly physiological function. Crystallization,
site-directed mutagenesis, and comparisons of protein secondary
structure have provided insight into the mechanisms of several bile
acid-biotransforming enzymatic reactions. Molecular cloning of genes
encoding bile salt-modifying enzymes has facilitated the understanding
of the genetic organization of these pathways and is a means of
developing probes for the detection of bile salt-modifying bacteria.
The potential exists for altering the bile acid pool by targeting key
enzymes in the 7alpha/beta-dehydroxylation pathway through the
development of pharmaceuticals or sequestering bile acids biologically
in probiotic bacteria, which may result in their effective removal from
the host after excretion.
PMID: 16299351
# 3 looks like a possible scenario I can grasP,
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=11843027
H. Pylori is ubiquitous to the point that there may be shared pathways
with P and GSD.
Well? Additional searches should include my pet LPS or endotoxin.
But why bother? Just change your gut flora and your in the pink. lol
And enjoy life,
http://katherine09267.tripod.com/ka...x.album?i=0&s=1
& the Mona Lisa smile,
http://www.parismuse.com/about/news/da-vinci-code.shtml
Add uP to uridine!
randall... or - your a bean! Human one at that, sprout where planted!
[vbcol=seagreen]
> --
> With good thoughts,
> Benjamin Blavat
>
>
>
>
> "randall" <ranhub11@aol.com> wrote in message news:1148509143.445849.223090@i39g2000cwa.googlegroups.com...
| |
| randall 2006-06-04, 9:15 am |
|
Benjamin Blavat wrote:
> Hi,
>
> In trying to find a cure for what causes Psoriasis. I believe I am now
> closer than ever. I still believe its has a fungal component, but the
> mechanism locking us from clearing turns out I believe, is not enough bile
> being delivered to digest the food we eat by ourselves!
OK , ok i know we've done this reply once already.
Lets go smaller. Not nanobac's but viral this time.
If your treating for fungi you may inadvertently be knocking back
a viral thingy.
What does P and Cancer have in common with their DNA?
http://www.emediawire.com/releases/2006/5/emw390668.htm
[...]
So here is the mystery. If the gene is not mutated in the great
majority of the breast cancer patients, why are the tumors showing low
levels of the BRCA1 protein? Today, this is one of the biggest
mysteries in cancer research.
The BRCA1 gene is not unique. Many normal (perfect shape, non-mutated)
genes exhibit a mysterious abnormal (increased or decreased) production
of proteins in cancer. Moreover, studies also report abnormal gene
expression of normal genes in other diseases, such as atherosclerosis,
obesity, osteoarthritis, type II diabetes, alopecia, type I diabetes,
multiple sclerosis, asthma, lupus, thyroiditis, inflammatory bowel
disease, rheumatoid arthritis, psoriasis, atopic dermatitis, and graft
versus host disease. <sniP>
------------------------------------------------------
So what's the cause?
http://www.causeofcancer.org/
[...]
To summarize: the cause of cancer, and other chronic diseases, is not a
genetic mutation, or damaged DNA, it is a reallocation of a scarce
genetic resource caused by the latent presence of a virus (or other
types of foreign DNA).
<sniP>
It's the viral crap! Looks like a good idea to me.
Didn't Uwe find his CFS cure by looking at the virusmyth site?
Uwe posted like 20 different pages from that site.
I know, i reposted all of the virus myth pages already.
I'll find them now,
http://groups.google.com/group/alt....199002a4a1471bb
Scrool down and you'll see them.
Whatever uwe's secret is we can be sure he's treating something in a
pathway
for virus.
And I know that i cleared with shegoi's creosote product that directly
kicks rear end on the little viral critters during the worse months of
the year
for psoriasis.
Should we plan on attacking on multiple levels?
If uwe got the results he did, then maybe CFS is like P in that
it stimulates a th1 response due to virus, but uses up something that
can be
suPPlemented for!
I never took him seriously. Now i'm willing to go back over old ground.
My only problem now is i've cleared to sub 3% levels with the
IP6, vitamin C and HA etc. that i've been on for 10-11 months.
I do continue to supplement with proflora whey and a raft of things,
but I consider the whole whey to be #1 on the list for staying clearer.
<sniP>
This breast cancer research is right on. WE need to look at this
closer!
I'll pubmed it tomorrow for a hour or so.
randall... round n round we go, what bug we stoP on nobody knows!
| |
| randall 2006-06-04, 9:15 am |
|
<sniP>
> I'll pubmed it tomorrow for a hour or so.
>
> randall... round n round we go, what bug we stoP on nobody knows!
Yikes!
Indy day is preventing me from concentrationg...
Marco Andretti is running 5th and Danica is 9th with 66 laps run.
If wheldon can hang on he's got two in a role. Somebody crashed..
Good time to do this post....(go to the end of this post for more indy
jpgs)
Ok, back to my hodge podge du jour for P.
Whats the easiest way to think of virus in the body?
How about warts?
http://www.kentucky.com/mld/kentucky/14686381.htm
[...]
If cost isn't an issue, Coverman calls imiquimod cream (sold under the
brand name Aldara) "a great treatment." It boosts the immune reaction
to warts and helps the body battle HPV.
<sniP>
Using imiquimod is like creating a mini Th1 response where the toPical
is used.
Since we are psoriatics, we have high levels of Th1 systemic wide and
that may be a reason why psoriatics get less cancer as a group.
So, in order to get rid of a wart, creating an inflammatory response is
sometimes
necessary.
Let's consider the same idea with disease versus disease.
http://www.xagena.it/news/medicinen...d9a4ca9274.html
How one disease may prevent another
The knowledge that one disease may prevent the onset of another is not
new. For example, the discovery that cowpox vaccines can prevent
smallpox dates back to 1798.
E. Richard Stiehm, at the Mattel Children's Hospital at UCLA,
researched examples throughout medical history of ways that one disease
prevents another.
His findings suggest that genetic, infectious and metabolic influences
should be considered when looking for treatments, particularly in
regard to HIV/AIDS.
" Clinical observations of disease-versus-disease interactions have led
to an understanding of the mechanisms of several diseases," Stiehm
said. " In turn, these observations have led to the development of
vaccines, therapeutic antibodies, medications and special diets."
Stiehm's research illustrated 12 disease pairs, reviewed their
therapeutic implications and suggested additional applications.
A few of the pairings that Stiehm described include:
Sickle cell disease and malaria. In 1948, British biologist J.B.
Haldane proposed that malaria was an evolutionary force for selecting
malaria-resistant genes. He suggested that those carrying the gene for
sickle cell anemia were better able to survive in malaria-infected
areas.
Leprosy patients have severe immune defects and cutaneous anergy -- an
inability to respond to skin testing. They hardly ever get psoriasis, a
skin disorder.
Starvation was used since biblical times for the treatment of seizures,
which were believed to be demons.
A 1924 discovery showed that a diet rich in fat and low in
carbohydrates mimicked starvation by causing ketonemia and also
controlled seizures. The ketogenic diet is still used today for cases
of epilepsy resistant to medication.
During the 1994 winter of starvation when bread supplies to the
children's hospital were interrupted at The Hague, young patients with
celiac disease, a digestive disease that damages the small intestine
and interferes with absorption of nutrients from food, thrived on their
"non-bread" diet. Wheat was discovered to be the culprit.
Other diseases that benefit from severe caloric or protein restriction
include kidney failure, type-II diabetes, inflammatory bowel disease
and morbid obesity.
Overall, Stiehm proposed that new evidence can be found for using
certain viruses to treat diseases such as HIV, which do not respond to
other medications.
" There have been several studies indicating that HIV patients
co-infected with a virus related to hepatitis C, called GB virus C,
have less severe HIV disease and improved survival," Stiehm said.
Stiehm got the idea for his historical review from cases he saw while a
pediatric resident at Babies Hospital in New York City.
One case was a kidney disease patient with nephrosis who was
unresponsive to medications but went into remission after contracting
measles.
The other, a cystic fibrosis ( CF ) patient who needed to be admitted
to the hospital, but there were no rooms available. Stiehm's
supervisor, a CF specialist, told him, " put him in the room with the
tuberculosis patient -- CF patients never get tuberculosis." Subsequent
studies have confirmed this observation.
Source: university of California - Los Angeles, 2006
randall note:: crap! I don't want to be a lePer to quell P! Nothing
like going
from the frying pan to the fire. Yet, can the virus for leprosy prevent
P without having to be a lePer?
Recently, i've been on a breast cancer thing.
http://groups.google.com/group/alt....arch+this+group
Thats a little broad, let's shorten it.
http://groups.google.com/group/alt....rt=0&scoring=d&
And some more,
http://groups.google.com/groups/sea...sis&qt_s=Search
That post by Anh Le is interesting.
I posted a topical treatment by a 95y/o man for bcc/scc using efudex
and DMSO about
a week or so back.
http://groups.google.com/groups/sea...dex&qt_s=Search
Let's do some RNA to see what;s new in that venue.
=====================================================
http://www.signaling-gateway.org/up...05/nri1856.html
RNA viruses: all bases covered
The cytoplasmic helicase proteins MDA5 and RIG-I have differential
roles in viral dsRNA recognition.
The cytoplasmic pattern-recognition receptors
melanoma-differentiation-associated protein 5 (MDA5) and
retinoic-acid-inducible gene I (RIG-I) have both been shown to
recognize polyinosinic-polycytidylic acid (poly I:C), which is a
synthetic analogue of double-stranded RNA (dsRNA) that is used as a
mimic of RNA-virus infection. In addition, RIG-I has been shown to be
crucial for the recognition of several RNA viruses, but the function of
MDA5 in vivo and the relationship between these two receptors in vivo
were not known. Now, Shizuo Akira and colleagues show that MDA5 and
RIG-I recognize different types of RNA virus and are important for host
defence against these particular viruses.
To study the in vivo function of MDA5, the authors generated
MDA5-deficient mice and examined their response, together with the
response of RIG-I-deficient mice, to poly I:C. In support of previous
(in vitro) studies, MDA5 was shown to be crucial for the production of
type I interferons (that is, IFNalpha and IFNbeta), an early step in
antiviral immune responses. However, in contrast to these previous in
vitro studies, RIG-I was found to be dispensable for poly-I:C-induced
type-I-IFN production in vivo. Furthermore, RIG-I was shown to be
required for IFNbeta production by mouse embryonic fibroblasts (MEFs)
in response to in vitro-transcribed dsRNAs, whereas MDA5 was not. Taken
together, these results indicate that MDA5 and RIG-I can detect
different types of dsRNA.
This finding raised the possibility that these receptors recognize
different RNA viruses, so the authors assessed the cytokine response of
MEFs to single-stranded RNA (ssRNA) viruses (for which dsRNA is a
replication intermediate) belonging to various virus families. RIG-I,
but not MDA5, was required for the detection of several negative-sense
ssRNA viruses (including influenza virus) and a positive-sense ssRNA
virus, Japanese encephalitis virus (which is a flavivirus). By
contrast, MDA5, but not RIG-I, was required for the detection of a
positive-sense ssRNA virus, encephalomyocarditis virus (which is a
picornavirus). Moreover, RIG-I-deficient mice and MDA5-deficient mice
were highly susceptible to infection with the respective viruses,
confirming that this receptor-mediated viral recognition has an
important role in host defence.
MDA5 and RIG-I are therefore crucial for the recognition of different
groups of viruses. How these receptors detect different viral RNAs
remains unclear, and the authors suggest that analysing the crystal
structures of the helicase (RNA-binding) domains of these proteins
might shed light on the molecular mechanisms of this differential
recognition.
Davina Dadley-Moore
References
1. Kato, H. et al. Differential roles of MDA5 and RIG-I helicases in
the recognition of RNA viruses. Nature 441, 101-105 (04 May 2006)
------------------------------------------------------------------------
Cortistatin to the rescue
Two studies show that a recently discovered endogenous factor,
cortistatin, is an effective anti-inflammatory factor which could be
used to treat inflammatory disorders such as Crohn's disease and septic
shock. The quest to find specific, effective and safe therapeutic
agents for inflammatory disorders such as Crohn's disease and septic
shock is an ongoing struggle. Now, two new studies by Gonzalez-Rey et
al. describe a recently discovered endogenous factor, cortistatin, as
an effective anti-inflammatory factor and a potential multistep
therapeutic agent for inflammatory disorders
Cortistatin is related to the cyclic neuropeptide somatostatin, which
has been shown to have immunomodulatory properties. Administration of
cortistatin 12 hours after induction of colitis using
2,4,6-trinitrobenzene sulphonic acid (TNBS) in mice - which is a
model similar to human Crohn's disease in its clinical, pathological
and immunological features - protected mice against colitis
development. Administration of cortistatin to TNBS-treated mice
ameliorated the associated histopathology and clinical symptoms of
TNBS-induced colitis, including weight loss, diarrhoea, intestinal
inflammation and mortality. Interestingly, treatment with cortistatin 6
days after TNBS administration abrogated ongoing disease and was also
effective at reducing disease recurrence.
Analysis of the inflammatory mediators in the colon showed a
substantial reduction in the production of various pro-inflammatory
cytokines and chemokines in mice treated with cortistatin. Decreased
infiltration of inflammatory cells in the colonic mucosa was also
observed. However, it would seem that the decrease in cytokine and
chemokine production was not a result of reduced numbers of
infiltrating cells but of direct suppression of lamina-propria
mononuclear cells. In addition, CD4+ T cells isolated from
cortistatin-treated mice with colitis produced less interferon-gamma
(IFNgamma) than T cells from untreated mice with colitis.
Interestingly, cortistatin treatment also increased the production of
the anti-inflammatory cytokine interleukin-10 (IL-10). Indeed, the
number of IFNgamma-producing CD4+T cells isolated from the lamina
propria was decreased following cortistatin treatment, whereas the
number of IL-10-producing cells was increased. This observation
indicates that cortistatin induces the generation and/or activation of
IL-10-producing T cells that might contribute to the observed
protection against colitis development.
In a separate study, this group also showed a protective role for
cortistatin in a model of septic shock. Administration of cortistatin
protected mice against endotoxin-induced lethality and associated
histopathology. These effects seem to be mediated through the
suppression of pro-inflammatory cytokine, chemokine and acute-phase
protein production. Cortistatin treatment was also associated with
increased IL-10 production in this model.
These data indicate that cortistatin is a potent anti-inflammatory
agent that suppresses the production of pro-inflammatory mediators
while increasing IL-10 production in two different disease models.
Therefore, the authors suggest that cortistatin might represent a
potential therapeutic agent for Crohn's disease and septic shock.
-------------------------------------------------------------------
Anchors away!
A loss of function analysis reveals that IMPs (IGF-II mRNA-binding
proteins) are directly involved in the post-transcriptional regulation
of mRNAs encoding extracellular matrix and adhesion proteins.
The RNA-binding proteins IMPs (IGF-II mRNA-binding proteins) have been
implicated in mRNA localization, nuclear export and translational
control. Reporting in The EMBO Journal, Vikesaa and colleagues now show
that two IMP proteins, IMP1 and IMP3, also have profound effects on
cellular adhesion and invasion during development and cancer formation.
In an attempt to understand the cellular functions of the IMPs, Vikesaa
et al. used RNA interference (RNAi) and selectively knocked down IMP1
and IMP3 in HeLa cells. Cells that were treated with small interfering
RNAs against IMP1 and IMP3 became spindle-shaped, rounded and had fewer
cellular extensions. Cell-cell contacts were severely reduced and the
number of cells that were floating in the media indicated that IMP
depletion resulted in cell detachment. Using confocal microscopy
combined with a matrix-degradation assay, the authors also showed that
the loss of IMPs almost completely disrupted the formation of
invadopodia - actin-rich structures that degrade and extend into the
extracellular matrix during cell migration.
But how do IMPs regulate adhesion and invasion? Although the IMP
proteins have been extensively studied, only a few RNA targets have
been reported so far. So to identify novel factors and pathways that
are regulated by IMP proteins and to dissect the mechanisms behind the
phenotypic changes that were observed, the authors compared the
gene-expression profiles of IMP RNAi-treated and control cells. They
found that the levels of only 27 transcripts changed significantly -
7 transcripts were upregulated and 20 were downregulated. Strikingly,
despite the small number of transcripts that were identified, 11 of the
transcripts that were downregulated encoded for proteins that are
involved in cellular adhesion and/or invasion.
Of these transcripts, the authors further characterized CD44, a
hyaluronic-acid receptor that has been previously implicated in
cell-matrix adhesion and the formation of invadopodia. Could CD44 be
a direct target of IMPs, and could the reduction of CD44 mRNA have a
role in the loss of invadopodia in IMP-depleted cells? The CD44 gene
generates three transcripts by alternative polyadenylation and Vikesaa
et al. not only showed that the selective knockdown of the longer
transcript recapitulated the effect of IMP depletion and reduced the
number of cells with invadopodia, they also found that IMP1 binds to
and stabilizes this transcript.
These findings show that IMPs are involved in cell adhesion and the
formation of invadopodia by regulating mRNA target genes that are
involved in these processes. IMPs are expressed in various cancers, but
whether the overexpression of IMPs in cancer cells might promote their
invasive capacity remains to be seen.
--------------------------------------------------------
http://www.eurekalert.org/pub_relea...o-mlk052606.php
Mice lacking key immune component still control chronic viral
infections
Despite lack of a key component of the immune system, a line of
genetically engineered mice can control chronic herpes virus
infections, researchers at Washington university School of Medicine in
St. Louis have found.
Scientists can't prove it yet, but they suspect the missing immune
system component, a group of molecules known as the Major
Histocompatibility Complex (MHC) Class Ia, has a previously
unrecognized backup that is similar enough to step in and fill the void
left by its absence. If so, that backup may become a new focus for
efforts to design antiviral vaccines.
"This surprising finding contradicts a long-held belief about control
of viral infection: that the immune system must have MHC Class I
molecules to recognize and destroy virus-infected cells," says senior
author Skip Virgin, M.D., Ph.D., professor of pathology and immunology
and of molecular microbiology. "It also suggests that we may need to
take a more extensive look at what immune system elements play a role
in controlling chronic viral infections."
The study will be published in the May issue of Public Library of
Science Pathogens.
In chronic herpes virus infections, the body brings the invader under
control, reducing its replication and spread, but is unable to
completely eliminate it, resulting in lifelong infection.
<sniP>
------------------------------------------------
Breakthrough for systemic RNAi
Systemic delivery of small interfering RNAs (siRNAs) in stable nucleic
acid-lipid particles silences the disease target apolipoprotein B
(ApoB) in monkeys.
RNAi has become a powerful research tool, but progress in developing
therapeutic applications of this technology has only recently started
to gather momentum. In a major advance for this field, Zimmermann,
MacLachlan and colleagues report the first demonstration of gene
silencing in non-human primates after systemic delivery of small
interfering RNA (siRNA).
RNAi-based therapeutics harness an endogenous cellular regulatory
mechanism in which small dsRNA molecules, or siRNAs, bind to and
mediate the destruction of specific mRNA molecules, preventing their
translation into protein. Despite its great potential, moving siRNA
forward into the clinic is beset by problems with siRNA stability and
in vivo delivery. Current siRNA-based drugs in clinical development
rely on direct delivery to the diseased tissue (by injection, for
example). Until now, few studies have reported successful systemic
siRNA delivery even in rodent models, and strategies to achieve this
are highly sought after. In this study, two collaborating groups
targeted a clinically relevant gene, apolipoprotein B (APOB), in a
non-human primate using systemically delivered siRNA.
siRNA can target molecules that conventional therapeutics cannot reach.
One such target is APOB, a component of low-density lipoprotein (LDL),
which is involved in cholesterol transport and metabolism, and is
linked with various coronary diseases. Conventional drugs are
available, but suffer from variable response and delayed efficacy; new
strategies to reduce LDL are therefore in demand, making APOB an
important target.
Following previous work, in which Apob was successfully silenced in
rodents, the researchers set out to translate this strategy to a more
clinically relevant model, the cynomolgus monkey. Importantly, to
achieve selective and efficient delivery to the liver, where APOB RNA
is synthesized, siRNA was encapsulated into small stable nucleic
acid-lipid particles (SNALP), which remain stable in the bloodstream
and are readily taken up by liver cells. Beginning as early as 24 hours
after a single intravenous dose of siRNA, a drop in APOB protein, LDL
and cholesterol levels lasting at least 11 days was observed. This was
associated with a 90% reduction in APOB mRNA levels in the liver that
was shown to be mediated by RNAi. Interestingly, the gene-silencing
effect was both stronger and longer-lasting than had been predicted
from rodent studies - an early indication of some potentially useful
therapeutic features of this agent.
No evidence of serious toxicity was observed; however, longer-term and
more detailed safety evaluations will clearly be required before this
technology can be transferred to the clinic. Nevertheless, this study
represents a crucial step forward in the application of RNAi-based
therapeutics, demonstrating the potential for siRNA to be delivered
systemically and therefore opening up the range of diseases that could
be tackled using this technology.
++++++++++++++++++++++++++++++++++++++++++++++++++++++
======================================================
+++++++++++++++++++++++++++++++++++++++++++++++++++++++
OK, the race is on LAP 73
I'll post my latest work on Uridine and skew it towards the above.
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=16720550
APOBEC family proteins: novel antiviral innate immunity.
Takaori-Kondo A.
Department of Hematology and Oncology, Graduate School of Medicine,
Kyoto University, Kyoto, Japan. atakaori@kuhp.kyoto-u.ac.jp
APOBEC3G has been identified as an anti-human immunodeficiency virus
type 1 (HIV-1) host factor that belongs to the APOBEC superfamily of
cytidine deaminases. It deaminates cytidine to uridine in nascent
minus-strand viral DNA, inducing G-to-A hypermutation in the
plus-strand DNA of HIV-1. The accumulating evidence demonstrates that
APOBEC family proteins also have an antiviral activity against a wide
variety of viruses, including not only retroviruses but also other
types of viruses, and that each virus seems to have its own strategy
for escaping from APOBEC proteins. These results suggest that the
APOBEC3 family plays an important role in antiviral host defense as an
innate immunity. Recent progress in research on APOBEC family proteins
is reviewed.
PMID: 16720550
An overview of cytidine deaminases.
Navaratnam N, Sarwar R.
MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College,
London, United Kingdom. naveenan.navaratnam@csc.mrc.ac.uk
Enzymes that deaminate cytidine to uridine play an important role in a
variety of pathways from bacteria to man. Ancestral members of this
family were able to deaminate cytidine only in a mononucleotide or
nucleoside context. Recently, a family of enzymes has been discovered
with the ability to deaminate cytidines on RNA or DNA. The first member
of this new family is APOBEC1, which deaminates apolipoprotein B
messenger RNA to generate a premature stop codon. APOBEC1 has the
conserved active site motif found in Escherichia coli cytidine
deaminase. In addition, APOBEC1 has a unique motif containing 2
phenylalanine residues and an insert of 4 amino acid residues across
the active site motif. This motif is present in APOBEC family members
including activation-induced cytidine deaminase (AID), APOBEC2, and
APOBEC3A through APOBEC3G. AID is essential for initiating class-switch
recombination, somatic hypermutation, and gene conversion. The APOBEC3
family is unique to primates. APOBEC3G is able to protect cells from
human immunodeficiency virus and other viral infections. This function
is not unique to APOBEC3G; other APOBEC3 family members also have this
ability. Overexpression of enzymes in this family can cause cancer,
suggesting that the genes for the APOBEC family of proteins are
proto-oncogenes. Recent advances in the understanding of the mechanism
of action of this family are summarized in this review.
PMID: 16720547
With all the Brca1 breast cancer stuff this one is interesting,
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=16720348
Uridine phosphorylase in breast cancer: a new prognostic factor?
Yan R, Wan L, Pizzorno G, Cao D.
Department of Medical Microbiology, Immunology, and Cell Biology,
Cancer Institute, Southern Illinois university School of Medicine,
Springfield, IL 62702, USA.
Uridine phosphorylase (UPase) is an enzyme that converts the pyrimidine
nucleoside uridine into uracil. Upon availability of
ribose-1-phosphate, UPase can also catalyze the formation of
nucleosides from uracil as well as from 5-fluorouracil, therefore
involved in fluoropyrimidine metabolism. UPase gene expression is
strictly controlled at the promoter level by oncogenes, tumor
suppressor genes, and cytokines. UPase activity is usually elevated in
various tumor tissues, including breast cancer, compared to matched
normal tissues and this induction appears to contribute to the
therapeutic efficacy of fluoropyrimidines in cancer patients. In this
review, we will discuss in detail the role of UPase in the activation
of fluoropyrimidines and its effect on the prognosis of breast cancer
patients.
PMID: 16720348
Hey Shaq! Put me down, i've got a race to win,
http://ilikeracing.com/u/shaq_castroneves375.jpg
No way dude!
http://www.indyjapan.com/indyracing...nny/wheldon.png
Eat my tail piPe!
----------------------------
Only till we laP you,
http://www.indy500.com/news/2005/im...85-12222005.jpg
randall... my P needs a Pit stoP! Kicking viral behinds laP after
laP...
| |
| manfred95@lycos.com 2006-06-04, 9:15 am |
| Pathophysiology. 2004 Dec;11(3):139-145. Related Articles, Links
Bile acids in physico-chemical host defence.
Bertok L.
"Fodor Jozsef", National Center of Public Health, "Frederic
Joliot-Curie" National Research Institute for Radiobiology and
Radiohygiene, P.O. Box 101, H-1775, Budapest, Hungary.
The discovery of the physico-chemical host defence is closely connected
with the endotoxin research. It is well known that the toxic effects of
endotoxins under experimental conditions can be induced only when they
are administered parenterally. However, in naturally occurring
entero-endotoxemic diseases (e.g. septic and various shocks, etc.), the
endotoxin is absorbed from the intestinal tract. The cause and mode of
translocation have been unknown. The generally used experimental shock
models differ from natural diseases only in the mode by which endotoxin
enters the blood circulation. If the common bile duct of rats was
chronically canulated (bile-deprived animals) orally administered
endotoxin was absorbed from the intestinal tract into blood circulation
and provoked endotoxin shock. This translocation of endotoxins and the
consequent shock can be prevented by sodium deoxycholate or natural
biles. The bile acids split the endotoxin macromolecule into atoxic
fragments. A similar detoxifying detergent action plays a significant
role in host defence against infectious agents with outer lipoprotein
structure (e.g. so-called 'big' viruses). This defence mechanism of
macroorganisms based on the detergent activity of bile acids
(end-products of the cholesterol metabolism) is called as
physico-chemical defence system. Therefore, bile deficiency and the
consequent endotoxemia are important components in the pathogenesis of
certain diseases (e.g. sepsis, intestinal syndrome of radiation
disease, hepato-renal syndrome, parvovirus infection, herpes,
psoriasis, atherosclerosis, etc.). Bile acids may be used for the
prevention and/or therapy of the above mentioned clinical conditions.
PMID: 15561510 [PubMed - as supplied by publisher]
Pathophysiology. 2003 Dec;10(1):57-61. Related Articles, Links
Pathophysiology of psoriasis: coping endotoxins with bile acid therapy.
Gyurcsovics K, Bertok L.
"Petz Aladar" County Hospital, Gyor, Szent Imre u. 41, H-9024, Hungary
The authors have tested the hypothesis that the deficiency of bile
acids and the consequent endotoxin translocation might play a role in
the pathogenesis of psoriasis. Under normal conditions the bile acids
act as detergents (physico-chemical defense) and can protect the body
against enteric endotoxins by splitting them into nontoxic fragments
and thus preventing the consequent release of cytokines [Persp. Biol.
Med. 21 (1977) 70]. A total of 800 psoriasis patients participated in
the study and 551 were treated with oral bile acid (dehydrocholic acid)
supplementation for 1-8 weeks. The efficacy of the treatment was
evaluated clinically and also by means of the Psoriasis Area Severity
Index (PASI score). During this treatment, 434 patients (78.8%) became
asymptomatic. Of 249 psoriatics receiving the conventional therapy,
only 62 (24.9%) showed clinical recovery during the same period of time
(P<0.05). The curative effect of bile acid supplementation was more
pronounced in the acute form of psoriasis (95.1% of the patients became
asymptomatic). Two years later, 319 out of the 551 acute and chronic
psoriasis patients treated with bile acid (57.9%) were asymptomatic,
compared to only 15 out of the 249 patients (6.0%) receiving the
conventional treatment (P<0.05). At the end of the 2-year follow-up,
only 10 out of 139 acute psoriasis patients (7.2%) receiving the
conventional therapy and 147 out of 184 bile acid treated patients
(79.9%) were asymptomatic (P<0.01).To conclude, the results obtained
suggest that psoriasis can be treated with success by oral bile acid
supplementation presumably affecting the microflora and endotoxins
released and their uptake in the gut.
PMID: 14643904 [PubMed - as supplied by publisher]
| |
| sherrybove@gmail.com 2006-06-04, 9:15 am |
| Measles is one of the most contagious viral diseases. It is caused by
paramyxo virus and is the most unpleasant and the most dangerous of the
children's diseases that result in a rash. This is due to the
complications of the disease.
How is measles transmitted?
* Droplets transfer the infections. Although the sick person may be in
isolation, the disease may still spread from room to room.
* Anybody who has not already had measles can be infected.
* Infants up to four months of age will not be infected if their mother
has had measles herself because they will be protected by her
antibodies.
Symptoms of measles include:-
a fever at about 39=BAC.,a cold, coughing, possibly with a barking
cough, sore throat - the lymph nodes in the throat may swell, reddish
eyes etc.
For more information on measles :-
http://www.medical-health-care-info...ren/measles.htm
| |
| manfred95@lycos.com 2006-06-07, 2:29 am |
|
Cruiser,
What happened with your enzyme trial? Was it a bust?
No one responded to my post about the Hungarian bile salts abstract:
"During this treatment, 434 patients (78.8%) became
asymptomatic. The curative effect of bile acid supplementation was more
pronounced in the acute form of psoriasis (95.1% of the patients became
asymptomatic).
..... the results obtained suggest that psoriasis can be treated with
success by oral bile acid
supplementation presumably affecting the microflora and endotoxins
released and their uptake in the gut.
Isn't there anyone out there who has tried this? Seems like the first
thing to try if this were true.
Is it safe to supplement with dehydrocholic acid? 'Haven't had a
chance to research this as I have been away for awhile.
(I am excited about your carnosine/vitamin E trial, also)
| |
|
| Hi Manfred,
At the moment, I'm down to approximately 2 to 3% coverage which I mainly
attribute to a strict diet and lots of fish oils. I've tried digestive
enzymes in the past with no results but I've never tried the bile salt
approach which definitely sparked my interest. So I've just begun taking a
bile salt supplement from Trophic up here in Canada with the ingredients
listed here.
http://www.trophic.net/d1.html
I have no idea if it's strong enough to make any kind of difference but I
thought I'd give it a shot and see what happens over the next while. The
bile salts are from Ox but hopefully I don't end up getting Mad Ox disease!
:-)
Brett
<manfred95@lycos.com> wrote in message
news:1149659109.954783.64720@h76g2000cwa.googlegroups.com...
>
> Cruiser,
> What happened with your enzyme trial? Was it a bust?
>
> No one responded to my post about the Hungarian bile salts abstract:
> "During this treatment, 434 patients (78.8%) became
> asymptomatic. The curative effect of bile acid supplementation was more
>
> pronounced in the acute form of psoriasis (95.1% of the patients became
>
> asymptomatic).
> .... the results obtained suggest that psoriasis can be treated with
> success by oral bile acid
> supplementation presumably affecting the microflora and endotoxins
> released and their uptake in the gut.
>
> Isn't there anyone out there who has tried this? Seems like the first
> thing to try if this were true.
> Is it safe to supplement with dehydrocholic acid? 'Haven't had a
> chance to research this as I have been away for awhile.
>
> (I am excited about your carnosine/vitamin E trial, also)
>
| |
| Cruiser 2006-06-07, 4:25 pm |
|
manfred95@lycos.com wrote:
> Cruiser,
> What happened with your enzyme trial? Was it a bust?
>
I tried only broad spectrum high potency digestive enzymes, without
anti-fungals. I did not see an benefit after going through the a bottle
and starting another. I still pop the odd one or two with a meal or
snack. However, I am no longer using them consistently.
After, gettng food poisoning on Friday, my stomach was a bit sensitive
and I did not take any for a few days, as a precaution. The clearing
affect that I am seeing now started when I started on carnosine and
vitamin E, without digestive enzymes.
Cruiser
| |
| Benjamin Blavat 2006-06-07, 9:24 pm |
| My Psoriasis continues to clear. I have only a few polyps with white heads
left here and there. I take 2 Pancreatin , and two Super strength enzyme
pills made by Vitaminworld, twice a day along with 200 mg Ketoconazole and
500 mg Greisofulvin prescription antifungals too. I also use the chewable
enzymes, they only have 1/10 the content but leave my teeth feeling very
clean. The antifungals might not be needed anymore as I believe that the
enzymes, may clear the reason I have the fungal symptoms. Since I spent so
much money, and the antifungals do help clear me, I feel I should take the
antifungals till finished.
For Psoriasis sufferer's, the application of simple bile may clear one up! I
did read that effect from snake bile on Psoriasis, but probably any bile
will do. I haven't found a butcher shop that gets their carcasses with the
internals still intake! The bile in the Super strength enzymes (bile - 400
mg) is my only source.
But remember that if these enzymes work for you, its only a stop gap measure
(a test or proof of concept), a more effective, more permanent clearing will
come after a purging of the liver and gall bladder of stones and sand.
Allowing a more normal delivery of bile, at the time of digestion. That is
my next step.
With good thoughts,
Benjamin Blavat
----- Original Message -----
From: <manfred95@lycos.com>
Newsgroups: alt.support.skin-diseases.psoriasis
Sent: Wednesday, June 07, 2006 1:45 AM
Subject: Re: You might want to try this out! Eat Pancreatic enzymes and use
Lamisil!
>
> Cruiser,
> What happened with your enzyme trial? Was it a bust?
>
> No one responded to my post about the Hungarian bile salts abstract:
> "During this treatment, 434 patients (78.8%) became
> asymptomatic. The curative effect of bile acid supplementation was more
>
> pronounced in the acute form of psoriasis (95.1% of the patients became
>
> asymptomatic).
> .... the results obtained suggest that psoriasis can be treated with
> success by oral bile acid
> supplementation presumably affecting the microflora and endotoxins
> released and their uptake in the gut.
>
> Isn't there anyone out there who has tried this? Seems like the first
> thing to try if this were true.
> Is it safe to supplement with dehydrocholic acid? 'Haven't had a
> chance to research this as I have been away for awhile.
>
> (I am excited about your carnosine/vitamin E trial, also)
>
| |
|
| What about this post from almost 8 years ago.
http://pinch.com/skinny?skin=pancreatin
Looks like the idea has been around for quite a while but maybe not enough
people have given it a long enough try?
Brett
"Benjamin Blavat" <ben14@adelphia.net> wrote in message
news:pNqdnccWW6s2zhrZnZ2dnUVZ_vqdnZ2d@adelphia.com...
> My Psoriasis continues to clear. I have only a few polyps with white heads
> left here and there. I take 2 Pancreatin , and two Super strength enzyme
> pills made by Vitaminworld, twice a day along with 200 mg Ketoconazole and
> 500 mg Greisofulvin prescription antifungals too. I also use the chewable
> enzymes, they only have 1/10 the content but leave my teeth feeling very
> clean. The antifungals might not be needed anymore as I believe that the
> enzymes, may clear the reason I have the fungal symptoms. Since I spent so
> much money, and the antifungals do help clear me, I feel I should take the
> antifungals till finished.
>
> For Psoriasis sufferer's, the application of simple bile may clear one up!
> I
> did read that effect from snake bile on Psoriasis, but probably any bile
> will do. I haven't found a butcher shop that gets their carcasses with the
> internals still intake! The bile in the Super strength enzymes (bile - 400
> mg) is my only source.
>
> But remember that if these enzymes work for you, its only a stop gap
> measure
> (a test or proof of concept), a more effective, more permanent clearing
> will
> come after a purging of the liver and gall bladder of stones and sand.
> Allowing a more normal delivery of bile, at the time of digestion. That is
> my next step.
>
> With good thoughts,
> Benjamin Blavat
>
> ----- Original Message -----
> From: <manfred95@lycos.com>
> Newsgroups: alt.support.skin-diseases.psoriasis
> Sent: Wednesday, June 07, 2006 1:45 AM
> Subject: Re: You might want to try this out! Eat Pancreatic enzymes and
> use
> Lamisil!
>
>
>
>
| |
|
| Oops! Sorry, I thought the link would take you to the post I was referring
to but I was wrong. It's the Pancreatin/Bromelain post, 4th one down the
page.
"Brett" <brettdaly@telus.net> wrote in message
news:uEIhg.21170$I61.8445@clgrps13...
> What about this post from almost 8 years ago.
> http://pinch.com/skinny?skin=pancreatin
>
> Looks like the idea has been around for quite a while but maybe not enough
> people have given it a long enough try?
>
> Brett
>
> "Benjamin Blavat" <ben14@adelphia.net> wrote in message
> news:pNqdnccWW6s2zhrZnZ2dnUVZ_vqdnZ2d@adelphia.com...
>
>
| |
| manfred95@lycos.com 2006-06-12, 2:29 am |
| More about bile acids:
J Dermatol Sci. 1998 Sep;18(1):35-42. Related Articles, Links
Erratum in:
J Dermatol Sci 1998 Nov;18(2):137.
Taurin-conjugated ursodeoxycholic acid has a reversible inhibitory
effect on human keratinocyte growth.
Yamaguchi Y, Itami S, Nishida K, Ando Y, Okamoto S, Hosokawa K,
Yoshikawa K.
Department of Dermatology, Osaka university School of Medicine, Japan.
Tauroursodeoxycholic acid (TUDC) is one of the most hydrophilic taurin
conjugated bile acids. TUDC has a suppressive effect on DNA synthesis
in primary cultured rat hepatocytes. In this study, we investigated the
growth inhibitory effect of TUDC on cultured human keratinocytes. TUDC
suppressed the proliferation of keratinocytes in a dose dependent
fashion, as measured by both cell counts and 5-bromo-2'-deoxyuridine
(BrdU) uptake. Keratinocytes reproliferated and reached almost the same
cell number as control after removal of TUDC from the medium. TUDC (1
mM) had no effect on the cell viability, as measured by the dye
exclusion test. Epidermal sheets stratified in the presence of TUDC
appeared thinner than those stratified without TUDC. These results
suggest that TUDC has a reversible growth suppressive effect on human
keratinocytes through the mechanism other than cytotoxicity and would
be applicable for the treatment of hyperproliferative skin disorders
such as psoriasis.
PMID: 9747660 [PubMed - indexed for MEDLINE]
| |
| manfred95@lycos.com 2006-06-12, 2:29 am |
| Pete,
You and Michael (msaintgeo@hotmail.com) were undertaking a trial a year
ago with bile acids after discussing this Hungarian study. Seems like
the discussion just evaporated. Did anything ever come of it?
http://groups.google.com/group/alt....515f5816889f267
| |
| DennisB99 2006-06-13, 4:25 pm |
| Thank you Mr. Blavat. Finally someone is talking about the fungal
component. My nails get horrible starting in May, then almost clear
through the winter, making me think there must be a fungal component.
Can you post a list of specific things to do, without getting too
technical? What enzymes to try? How much to take? what are the
specifics of the apple juice fast? What is an EPO? etc.
Dennis
zd57@comcast.net
| |
| randall 2006-06-13, 4:25 pm |
|
DennisB99 wrote:
> Thank you Mr. Blavat. Finally someone is talking about the fungal
> component.
It's been done 99 ways to sunday.
http://groups.google.com/group/alt....riasis&q=fungus
Over 400 hits. I've been in over 60 of those,
http://groups.google.com/group/alt....fungus+randall&
You can go to pubmed for more,
http://www.ncbi.nlm.nih.gov/entrez/...soriasis+fungus
H'mmm, that digs up an old bone around here,
http://www.ncbi.nlm.nih.gov/entrez/...soriasis+furfur
http://groups.google.com/group/alt....riasis&q=furfur
And back to pubmed for all furfur hits,
http://www.ncbi.nlm.nih.gov/entrez/...3&dopt=Abstract
> My nails get horrible starting in May, then almost clear
> through the winter, making me think there must be a fungal component.
You can put nails in the search boxes above for pubmed and see what
comes up.
Or simply do the same thing for our group.
> Can you post a list of specific things to do, without getting too
> technical?
Yes. Go to www.thewholewhey.com and do the wit kit and proflora
sweet whey for one month and it will go down to sub 2% levels and
your P will as well.
> What enzymes to try?
I used the N-zimes while on the above program. I don't see the
need after the first month or two and your colon flora has
switched to a slightly acidic medium.
> How much to take?
You need Bens inPut for digestive enzymes and Lamisil treatments. I
haven't
a clue on that program. Or just go to your health food store and
get some and fool around with dosage levels without going to far
astray of the directions.
> what are the
> specifics of the apple juice fast?
Do a fast and only cheat with you guessed it?
> What is an EPO?
Evening primrose oil?
> etc.
>
> Dennis
> zd57@comcast.net
Let us know how you do please.
randall...
| |
|
| Hi,
I'm taking the following from the book Eat Fat Lose Fat by Dr. Mary Enig, world-renowned expert on the biochemistry of food and fat.
When we eat fat, the gallbladder releases bile into the digestive tract to break the fat down into absorbable fatty acids. The gallbladder acts as a holding tank for the bile, which is secreted by the liver and is made out of cholesterol.
In our view, the presence of gallstones means that your body has increased its reservoir of cholesterol. If you have low cholesterol, your body needs such a reservoir on hand because it cannot be assured of getting adequate cholesterol from the bloodstream. Thus, it's actually counterproductive to reduce the fat in your diet, for this would only increase the body's tendency to store fat and hence to form gallstones. Instead, the best way to eliminate gallstones is to give your gallbladder the cholesterol it needs by eating adequate amounts of animal fats.
But it's crucial to eat the right fats. When people eat a lot of vegetable oils and trans fats, the gallbladder can become inflamed easily. That's yet another reason why eliminating those fats is so important. And when someone misguidedly follows a low-fat diet, the gallbladder stops working, still another harmful effect of the low-fat diets we've all been told are so healthy.
Anyway, that's her view as to why gallstones are formed and I thought I'd post it just in case it gives someone a clue as to why bile or pancreatin supplements might work for some people.
Brett
"Benjamin Blavat" <ben14@adelphia.net> wrote in message news:g6Kdnf2EubPu0erZnZ2dnUVZ_sGdnZ2d@adelphia.com...
Hey Randall,
No, don't have the Uwe formulation. Its just the evolution of my search system. Most research into Psoriasis follows the make up of the
plaques. I have been looking at the what (as in what causes it)! Psoriasis, seems to be for me, an undiagnosed Tinea infection, mine reacts to antifungal regimens, but they ultimately fail. So I looked for a locking mechanism. I thought it was Candida for many years. but my father's recent clearing in the hospital, was on top of a horrible case of Candida! So I looked for what else could be causing the failure of my immune system. that pointed to the liver and gallbladder, a failure of the bile system, its a good fit, now the question morphs to what causes the stones to form. If you read the website http://www.eczemacure.info That is where the witches fail for me. Their explanation as to why it works.
I am trying another brand of enzyme (2 for 1 Super Enzymes, Vitaminworld) right now while, waiting to get the "Pancreatin" from Vitaminworld, the Pancreatin seems to work better and is cheaper! Solgar " Pancreatin" is the brand from Edwin's website.
It seems so obvious to look at digestion as the cause of Psoriasis, but I could never put the tail on the donkey. This search should be right up your very talented alley. Find the causes of stones forming and accumulating, this should be the bottom line on our long term return to robust health. This is a real hard condition that could be the cause of the many different symptoms described throughout medicine without known cause.
We need data on what causes sand and stones to form and accumulate. From reading Edwin website, it seems clear to me that he is making new stones every month. So I figure bimonthly flushing to avoid any chance of non or low delivery of bile. It would seem to me that the makeup of bile would adapt over time to supply the exactly right enzymes you require for any diet available, making it preferable to taking the supplements for a long time, I believe with supplements there would be holes in your enzymes supply.
The supplements are the test that shows the need to cleanse the liver and gallbladder.
--
With good thoughts,
Benjamin Blavat
"randall" <ranhub11@aol.com> wrote in message news:1148509143.445849.223090@i39g2000cwa.googlegroups.com...
> OK BEN,
>
>
> FESS Up!
>
> Your taking Uwe's secret formula!?!?
>
> If not it sure sounds like it.
>
>
> If truly not, then congrats, your a true wonder man!
>
> The insipirations around here are astounding.
>
>
>
> ben wrote:
>
> Like what do you figure? Once a week, bi-weekly, monthly?
> One, two or more days at a time?
>
>
> Your saying the new suPPlement are the enzymes? Which brand?
>
>
> Wow wow wow. So what does your sweet heart say?
>
>
>
> How large where your plaques at the most recent time period when
> they were at least 6% pasi or more? Or should i say thickness etc.
>
>
>
> Wow.
>
>
> wow..
>
>
> I hope a bunch of folks verify this.
>
> Btw- how did you liver enzymes look before and after? I would think
> that some folks with high alt/ast may need to be quite cautious prior
> to embarking on this head strong.
>
> Don't pull a paul bragg on us now. He felt so good he accidentally
> died.
> But he felt great no doubt when he meet his fate,
> http://www.evolutionhealth.com/brag...le_fasting.html
>
> randall...
>
| |
| randall 2006-06-13, 4:25 pm |
|
> You can go to pubmed for more,
> http://www.ncbi.nlm.nih.gov/entrez/...soriasis+fungus
>
Let's tweak that last search for more juice,
http://www.ncbi.nlm.nih.gov/entrez/...20psoria*+fungi
Instead of psoriasis+fungus for about 150 hits, we can get almost 750
hits
with psoria* + fungi.
Now, if we can get some more folks relating their P to any and all
quirky things with fungus, who knows? Psoriatics may finally agree to
clean up the colon and take pressure off the liver for things to
try and resemble homeostasis.
Yet i'm the last one to talk. After finding the salvation i've gone
back
to testing suPPlements against individual pathways relating back to
inflammation. And now i'm on, the hoPefully, life extending alcar
supplement (ala + alc) twice a day.
I feel so young and vibrant i'm eating way in excess of those things
i should! Yet i'm not looking to worse for the war and tare. er wear
adn
tear... you know.
randall...its working! fingers are moving faster then brain now!
|
| |
|
|