Psoriasis support - Tazorac and Dithranol (Anthralin)

Author

Tazorac and Dithranol (Anthralin)

Richard Blackwood

2006-04-25, 6:21 pm

I have had limited success with Tazorac when I've tried it before.
Dithranol has always been the most effective for me. I can use the 3%
(Micanol) without any problems at all. My elbows have remained defiantly
resistant however. I think I've read somewhere that these two topicals can
be used in tandem. Does anyone have experience of using either of these
topicals in combo with others?

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randall

2006-04-26, 1:20 am

Richard Blackwood wrote:
> I have had limited success with Tazorac when I've tried it before.
> Dithranol has always been the most effective for me. I can use the 3%
> (Micanol) without any problems at all. My elbows have remained defiantly
> resistant however. I think I've read somewhere that these two topicals can
> be used in tandem. Does anyone have experience of using either of these
> topicals in combo with others?
>

Hi Richard,

I'm not a toPical guy. But i can try to run the keywords.

You may want to duplicate the effort substituting anthralin for
dithranol.

http://groups.google.com/groups/sea...ac+&qt_s=Search

http://www.ncbi.nlm.nih.gov/entrez/...t_uids=15180467
[...]
Tazarotene is an alternative for vitamin D(3) treatment if this
treatment fails. In some special cases, dithranol and tar treatment may
be used.
[...]
PMID: 15180467

http://www.ncbi.nlm.nih.gov/entrez/...t_uids=12639460
&
http://www.ncbi.nlm.nih.gov/entrez/...t_uids=10550358
[Tazarotene increases the antipsoriatic effect of dithranol in chronic
psoriasis]

Sander P, Happe M, Stucker M, Hermes N, Hoffmann K, Altmeyer P.

Dermatologische Klinik der Ruhr-Universitat, Bochum im
St.Josef-Hospital, Bochum.

We examined whether it is possible to increase the antipsoriatic action
by combining dithranol with a retinoid (tazarotene). In a randomized,
open, prospective study with 50 psoriatic patients (22 females, 28
males, PASI>10) the antipsoriatic effectiveness of dithranol
monotherapy to was compared combined therapy with dithranol and
retinoid. The combination dithranol/retinoid (collective 2, reduction
of the PASI from 17,2 to 2,8) revealed a significantly faster healing
than the dithranol monotherapy (collective 1, reduction of the PASI
from 18,5 to 4,8). The irritation of the combination therapy as
evaluated with clinical score and laser doppler imaging was increased.
Anti-psoriatic effectiveness of dithranol can be increased by combining
it with tazarotene.

PMID: 10550358

And the web if you haven't already tried,
http://www.google.com/search?q=Dith...rch&sa=N&tab=gw

randall

Richard Blackwood

2006-04-26, 6:20 pm

randall wrote:
<snipped but read>

Thanks Randall. Interesting stuff.
I see that Dovonex has been used in conjunction with dithranol so I may try
that. If I get any success I'll be sure to post it here!

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