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| Cruiser wrote:
> Currently, I am skeptical that folic acid is of any value to me.
> Folic acid in itself is not usable. It must undergo four chemical
> processes to be converted to methylfolate, which the my body can use.
> It is unclear to me that folic acid can be expected to reliably
> undergo those steps. It is known that some people cannot make the
> conversion. Consequently, I am trying to source some Natural Sources
> metafolin (methylfolate made by Merck), or see if I can get my local
> supplement store to buy a bulk amount from Merck, directly.
I came across this snippet:
http://www.findarticles.com/p/artic...ay/ai_100767845
High-dose folic acid for psoriasis - Literature Review & Commentary -
Brief Article
Townsend Letter for Doctors and Patients, May, 2003 by Alan R. Gaby
Seven patients with long-standing psoriasis were given 20 mg of folic
acid 4 times per day. Marked improvements were noted after 3-6 months of
treatment. Three additional patients who had previously received
methotrexate treatment for psoriasis were also given folic acid. In one
patient, new lesions appeared all over the trunk in places where they
had never existed. One patient showed decided worsening and the third
patient improved considerably.
Comment: The rationale for using high-dose folic acid is based on the
fact that allopurinol, a xanthine oxidase inhibitor, is effective
against psoriasis. The author of the present study has found that folio
acid fortified with specific amounts of ascorbic acid (to keep it in the
reduced state as tetrahydrofolate) is also an effective xanthine oxidase
inhibitor. Although no controlled trials have been done with folic acid,
other clinicians have observed the same beneficial effect against
psoriasis that Oster reported more than a quarter-century ago.
Methotrexate interferes with folic acid metabolism and, for reasons that
are not clear, appears to cause an adverse reaction to high-dose folic
acid in some cases. However, for patients who have not previously been
treated with methotrexate, folic acid appears to be a safe and promising
therapy for chronic psoriasis. Of course, when using high-dose folic
acid, it is important to remember that it can mask the laboratory
diagnosis of pernicious anemia.
Oster KA. A cardiologist considers psoriasis. Cutis 1977;20:39-41.
> At Randall's request, I am now adding an IP6/inositol mix to my
> supplements. He suggests that this is working well for him and would
> like to see how it works for me. IP6 has been shown to helpful in
> slowing or arresting uncontrolled cell growth in some cancers. Since
> psoriais manifests uncontrolled cell growth, and since Randall is
> reporting good results, this seems like a good idea.
What do you mean by IP6/Inositol mix? Are you planning on taking both
Inositol Hexaphosphate (IP6) and Inositol
--
All the best,
Pete
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