|
|
coastalguy wrote:
> Randall,
>
> fyi, This is the post to the Hep C newsgroup
> (concerning a current study) that caused my
> curiosity about Naltrexone:
>
> Cell Studies Shed Light on Liver Disease Immunology
> researchers have demonstrated that alcohol promotes
> the proliferation of hepatitis C virus in human
> liver cells. By studying molecular mechanisms in
> cell cultures, the researchers help explain the
> role of alcohol in aggravating hepatitis C
> infection and interfering with drug treatment for
> the infection. Infecting some 170 million people
> worldwide, hepatitis C virus is one of the leading
> known causes of liver disease in the United States.
>
>
> "It was already known that habitual alcohol
> drinkers have higher blood levels of hepatitis C
> virus, compared to infrequent drinkers, even when
> both are infected with the virus," said Wen-Zhe Ho,
> M.D., the director of retroviral research at The
> Children's Hospital of Philadelphia, who led the
> research team. "We investigated how alcohol affects
> the hepatitis C virus at the cellular level.
>
>
> Our study provides a biological mechanism to
> support clinical observations." The study appears
> in the July issue of Hepatology. The researchers
> found that alcohol increases the activity of a
> protein called nuclear factor kappa B, and thereby
> causes the hepatitis C virus to replicate, or
> produce multiple copies of itself. That protein is
> an important cellular regulator of gene products
> involved in inflammation. Furthermore, they found
> that alcohol interferes with the antiviral activity
> of interferon-alpha, a key therapy used for
> patients infected with hepatitis C.
>
> A third finding that may eventually have
> implications for patient treatment was that
> naltrexone, a drug used to help patients with
> alcoholism avoid relapse, may also block the
> deleterious effects of alcohol in promoting
> hepatitis C infection.
>
> The current research builds on previous research by
> the Children's Hospital team, which found that
> morphine also stimulates hepatitis C virus in liver
> cells by the same mechanisms as those found with
> alcohol.
>
> Both alcohol and morphine activate opioid systems
> present in liver cells, according to Dr. Ho. These
> systems contain biological pathways that produce
> natural opiates that may play a crucial role in
> drug and alcohol addiction. This process may
> explain why naltrexone, which blocks opiates from
> binding to their receptors on cell membranes,
> reduced the effects of alcohol in the current
> study. "Although further study is needed, our
> results suggest that naltrexone might supply
> additional benefits in reducing hepatitis C
> infection," said Dr. Ho.
>
> Ron
Dr Ho, retroviral ?
Not the doctor Ho, man of the year fraud ?
http://www.virusmyth.net/aids/data/cffiction.htm
Hep C is even a bigger fraud than hiv-aids.
Evidence for Hep C are based on the same shaky
foundations as hiv- evidence. There is no direct
isolation of the virus, in both cases.
http://www.virusmyth.net/aids/data/cjinterviewep.htm
I met a young woman, that tested positive, and
positive again on a repeat test. Then six months later
she was negative. And she never took any special
medication.
Uwe Hayek.
--
To be controlled in our economic pursuits,
is to be controlled in everything -- F.A.Hayek.
Magna est veritas et praevalebit
(great is truth, and shall prevail)
-- Del Kennedy
Government is not the solution,
government is the problem.
-- Ronald Reagan.
|
|