|
Home > Archive > Depression Medications > January 2005 > Niacin BURNS LIKE HELL
You are viewing an archived Text-only version of the thread.
To view this thread in it's original format and/or if you want to reply to
this thread please [click here]
| Author |
Niacin BURNS LIKE HELL
|
|
|
| Larry recommended Niacin for allergic rhinitis.
I got it and took some tonite.
Within 20 minutes my skin was so burning so hot, I felt like I was
sunburned all over by 200 degree sun!
What gives?
It sure doesn't feel like Niacin is an ANTI-INFLAMMATORY
It feels like Niacin is an inflamatory.
| |
|
|
"Linda" <adinllinda@aol.com> wrote in message
news:1106280833.484654.302100@c13g2000cwb.googlegroups.com...
> Larry recommended Niacin for allergic rhinitis.
>
> I got it and took some tonite.
>
> Within 20 minutes my skin was so burning so hot, I felt like I was
> sunburned all over by 200 degree sun!
>
> What gives?
>
> It sure doesn't feel like Niacin is an ANTI-INFLAMMATORY
> It feels like Niacin is an inflamatory.
>
niacin is a vasodilator. this means it opens up the little veins in your
skin and fills them with blood. this can cause flushing and burning. it
makes some people dizzy and pass out.
some drug dealers cut cocaine or meth with it because when you snort it, you
still get a "rush".
i've heard of B5 being used for allergic rhinitis, but not B3 (niacin).
-kelly
| |
|
|
metta wrote:
> "Linda" <adinllinda@aol.com> wrote in message
> news:1106280833.484654.302100@c13g2000cwb.googlegroups.com...
>
> niacin is a vasodilator. this means it opens up the little veins in
your
> skin and fills them with blood. this can cause flushing and burning.
it
> makes some people dizzy and pass out.
Burning like a hot red pepper for 15 minutes!
>
> some drug dealers cut cocaine or meth with it because when you snort
it, you
> still get a "rush".
>
> i've heard of B5 being used for allergic rhinitis, but not B3
(niacin).
What is B5? Folic Acid?
>
> -kelly
| |
|
|
"Linda" <adinllinda@aol.com> wrote in message
news:1106284014.174099.197660@c13g2000cwb.googlegroups.com...
>
> Burning like a hot red pepper for 15 minutes!
that's an adverse reaction. i wouldn't take it again.
> (niacin).
>
> What is B5? Folic Acid?
nope, Pantothenic Acid
http://www.diagnose-me.com/treat/T47895.html
-kelly
| |
|
|
metta wrote:
> "Linda" <adinllinda@aol.com> wrote in message
> news:1106284014.174099.197660@c13g2000cwb.googlegroups.com...
>
> that's an adverse reaction. i wouldn't take it again.
>
>
>
> nope, Pantothenic Acid
>
> http://www.diagnose-me.com/treat/T47895.html
Thanks, I will check it out.
| |
| Larry Hoover 2005-01-27, 8:19 am |
|
"metta" <culprit@flashmail.nospam.com> wrote in message
news:35bg8rF4hcv7vU1@individual.net...
>
> "Linda" <adinllinda@aol.com> wrote in message
> news:1106280833.484654.302100@c13g2000cwb.googlegroups.com...
NO! I was absolutely specific. I said niacinamide. Niacin causes a skin reaction,
the niacin flush, which is due to histamine release. Niacinamide acts in the
opposite way.
Niacin is the wrong substance. Niacinamide is the right one.
[vbcol=seagreen]
>
> niacin is a vasodilator. this means it opens up the little veins in your skin and
> fills them with blood. this can cause flushing and burning. it makes some people
> dizzy and pass out.
Correct.
Niacinamide has the opposite effect.
Niacin goes by two names. The older one, nicotinic acid, was changed to reduce
confusion with nicotine.
Niacinamide also goes by two names, the older one being nicotinamide.
If it doesn't end in -AMIDE, you've got the wrong stuff.
Lar
| |
|
|
Larry Hoover wrote:
> "metta" <culprit@flashmail.nospam.com> wrote in message
> news:35bg8rF4hcv7vU1@individual.net...
>
> NO! I was absolutely specific. I said niacinamide. Niacin causes a
skin reaction,
> the niacin flush, which is due to histamine release. Niacinamide acts
in the
> opposite way.
>
> Niacin is the wrong substance. Niacinamide is the right one.
>
in your skin and[vbcol=seagreen]
makes some people[vbcol=seagreen]
>
> Correct.
>
> Niacinamide has the opposite effect.
>
> Niacin goes by two names. The older one, nicotinic acid, was changed
to reduce
> confusion with nicotine.
>
> Niacinamide also goes by two names, the older one being nicotinamide.
>
> If it doesn't end in -AMIDE, you've got the wrong stuff.
Egads, Larry did say niacinamide!
Good, because I didn't care for the burning effect of niacin one bit.
I will look for niacinamide, thanks.
| |
| David W Studeman 2005-01-27, 8:19 am |
| On Thu, 20 Jan 2005 20:54:50 -0800, metta wrote:
>
> "Linda" <adinllinda@aol.com> wrote in message
> news:1106280833.484654.302100@c13g2000cwb.googlegroups.com...
>
> niacin is a vasodilator. this means it opens up the little veins in your
> skin and fills them with blood. this can cause flushing and burning. it
> makes some people dizzy and pass out.
>
> some drug dealers cut cocaine or meth with it because when you snort it, you
> still get a "rush".
>
> i've heard of B5 being used for allergic rhinitis, but not B3 (niacin).
>
> -kelly
True, B3 causes histamine release. I have been taking Niacin on and off
for years and the flushing becomes very tolerable in a few days although
it never goes away completely. I get just enough flush after taking it
that it also has nice psychochemical effects. Some take niacin right
before engaging in sex as the histamine release of orgasm is benefitted
by the histamine release of Niacin. Definitely NOT an antihistamine! It
can also be used to reverse the vasoconstriction of nicotine. It's
interesting to note that Niacin is also called Nicotinic Acid but has
reverse effects as far as blood vessels go from that of Nicotine.
Dave
| |
| David W Studeman 2005-01-27, 8:19 am |
| On Fri, 21 Jan 2005 08:42:53 -0500, Larry Hoover wrote:
>
> "metta" <culprit@flashmail.nospam.com> wrote in message
> news:35bg8rF4hcv7vU1@individual.net...
>
> NO! I was absolutely specific. I said niacinamide. Niacin causes a skin reaction,
> the niacin flush, which is due to histamine release. Niacinamide acts in the
> opposite way.
>
> Niacin is the wrong substance. Niacinamide is the right one.
>
>
> Correct.
>
> Niacinamide has the opposite effect.
>
> Niacin goes by two names. The older one, nicotinic acid, was changed to reduce
> confusion with nicotine.
>
> Niacinamide also goes by two names, the older one being nicotinamide.
>
> If it doesn't end in -AMIDE, you've got the wrong stuff.
>
> Lar
Niacinamide doesn't seem to work as well for many things you would use
mega doses of Niacin for. It'd probably prevent a deficiency but would be
useless for any effect. Niacinamide is actually the wrong stuff, save that
for One-A-Day vitamins.
Dave
| |
|
|
David W Studeman wrote:
> On Thu, 20 Jan 2005 20:54:50 -0800, metta wrote:
>
in your[vbcol=seagreen]
burning. it[vbcol=seagreen]
snort it, you[vbcol=seagreen]
(niacin).[vbcol=seagreen]
>
> True, B3 causes histamine release. I have been taking Niacin on and
off
> for years and the flushing becomes very tolerable in a few days
although
> it never goes away completely.
I gave niacin another try the last two days---but, at half the original
dose.
I still got a warm/hot red flush all over----but, not burning red hot
like that first time.
| |
| Larry Hoover 2005-01-27, 8:19 am |
|
"David W Studeman" <eat_your_own_spam@hormel.com> wrote in message
news:pan.2005.01.23.09.55.30.265984@hormel.com...
> On Fri, 21 Jan 2005 08:42:53 -0500, Larry Hoover wrote:
>
> Niacinamide doesn't seem to work as well for many things you would use
> mega doses of Niacin for. It'd probably prevent a deficiency but would be
> useless for any effect. Niacinamide is actually the wrong stuff, save that
> for One-A-Day vitamins.
>
> Dave
Niacinamide is not literally a substitute for niacin, which is used in megadoses to
treat hyperhomocysteinemia, for example. Specific to antihistaminic effects, though,
niacinamide is what you want. Moreover, it is niacinamide that goes on to promote
the formation of NADH, which is essential for the electron transport chain in
mitochondrial oxidative respiration.
The original poster was looking for an antihistaminic effect, not prohistaminic.
Niacinamide inhibits mast cell degranulation, and thus, histamine release. It also
is both a potentiator and partial agonist at the GABA-A receptor.
Lar
| |
|
|
"Larry Hoover" <larryhoover@sympatico.ca> wrote in message
news:g_7Jd.61$Yg6.36782@news20.bellglobal.com...
>
> "David W Studeman" <eat_your_own_spam@hormel.com> wrote in message
> news:pan.2005.01.23.09.55.30.265984@hormel.com...
>
your skin[vbcol=seagreen]
some[vbcol=seagreen]
reduce[vbcol=seagreen]
be[vbcol=seagreen]
that[vbcol=seagreen]
>
> Niacinamide is not literally a substitute for niacin
According to the literature I read---niacinamide and nicotinic acid are
metabolites of Niacin.
| |
|
|
I am not doubting you, this topic interests me as I have been worked up
for mastocytosis and I have severe head and neck flushing. Would you
please be kind enough to provide me with some further information on
this subject? No surprise, of course, that no MD's have mentioned this
yet!
Also, please don't take offense but I am just curious what your
credentials are, if any, or if you are just trying to help. I am just
curious what type of professional would know this type of information
and I was wondering if you were in the business somewhere. Again, I am
not trying to insult you, just trying to gauge the source/reliability
of this information. I have spent three miserable years being worked
up for every conceivable illness so I really do appreciate your post.
I am just a regular person and I have provided help to people in the
past even though I have no credentials, but I do know what I am talking
about in certain areas. You might be the same... again, please don't
take my inquiry the wrong way. :-)
Do you find that Niacinimide counteracts the flushing? If so, do you
have any idea of how it works? Do you recognize any distinction
between "flushing" and "head and neck flushing"?
For other people experiencing flushing, you might want to try a
Ventolin inhaler, beta blockers (such as Propanolol), and/or Singulair
(montelukast) as well as the commonly used H1 and H2 blockers -- should
be Zyrtec and Zantac. Do not use the generic version of Zantac as it
has a reputation of being inferior to the brand name. (hint: Zyrtec is
available OTC in Canada however in both generic and brand forms)
You might consider getting a simple but unusual blood test screening
for a substance called Tryptase and/or a skin biopsy from the commonly
afflicted area(s).
Anyone also experiencing Pruritus ("itching") can use sodium cromolyn
(same as Nasalcrom!) mixed into a lotion, for local application and
relief. (I personally haven't tried this yet, btw)
These haven't entirely worked for me but I have gone all the way to the
NIH with this, and these are the "best practices" I have found out
about so far. I am delighted to be able to share what I have learned.
Head and neck flushing shows up as symptoms in a few other illnesses,
including carcinoid tumor.
There is a very interesting article by Theoharis C. Theoharides (Tufts
University) in the Journal of Clinical Psychopharmacology (vol 22, #2,
page 103) regarding the relationship between anxiety and mast cell
releaase. Bottom line is, a course of anti-anxiety meds might help
also, as anxiety accelerates mast cell degranulation and histamine
release and hence flushing. I am on gobs of anti-anxiety meds and it
hasn't helped me from flushing but you never know I guess.
Hope this helps someone... If so, maybe the last three years hasn't
been a complete waste.
all the best to all you good people.
In article <g_7Jd.61$Yg6.36782@news20.bellglobal.com>, Larry Hoover
<larryhoover@sympatico.ca> wrote:
> Niacinamide is not literally a substitute for niacin, which is used in
> megadoses to
> treat hyperhomocysteinemia, for example. Specific to antihistaminic effects,
> though,
> niacinamide is what you want. Moreover, it is niacinamide that goes on to
> promote
> the formation of NADH, which is essential for the electron transport chain in
> mitochondrial oxidative respiration.
>
> The original poster was looking for an antihistaminic effect, not
> prohistaminic.
> Niacinamide inhibits mast cell degranulation, and thus, histamine release. It
> also
> is both a potentiator and partial agonist at the GABA-A receptor.
>
> Lar
>
|
| |
|
|