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derdrittemann2...@yahoo.com wrote:
> overma...@hotmail.com wrote:
>
Another example of the dearth of information that is so very telling.
> Yes. But the problem there is separating realcases of Lyme from real
> cases of ALS.
>
Yes that is a problem, but I'm not talking autoimmune nonsense.
example...
Detection and cellular localization of enterovirus RNA sequences in
spinal cord of patients with ALS
Berger, M.M, et al. "Detection and cellular localization of enterovirus
RNA sequences in spinal cord of patients with ALS." Neurology, Jan
2000, 54: 20-25.
Enterovirus infection has been suspected as a causative agent of ALS, a
motor neuron disease that leads to degeneration of motor neurons in the
brain stem leading to paralysis and death. In order to correlate
persistent enterovirus infection wit h the development of ALS, Berger
et al. Used RT-PCR and RT-IS-PCR on formaldehyde-fixed spinal cord
samples from 17 patients with ALS and 29 spinal cord samples from
control patients. The RT-PCR analysis revealed that in 88.3% of ALS
patients enterovirus nucleic acid was evident. Using the RT-IS-PCR
analysis, nucleic acid was also found in 76.4% of ALS. The neuronal
cells positive for viral genome were localized to the gray matter of
spinal cord patients with ALS. The detected enterovirus nucleic acid
was sequenced and in the 5* noncoding region there was an 86-94%
homology between the PCR products and the enterovirus echovirus 7. This
evidence suggests a strong relationship between the presence of
enteroviral genomic sequences in neurons and the development of ALS.
However, the evidence does not elucidate the mechanism that leads to
the destruction of motor neurons nor does it suggest that echovirus 7
is specifically the cause of ALS.
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