| JWissmille 2004-10-24, 2:08 am |
| =========================
"Emmy Kleineberger Nobel discovered L-forms at the Lister Institute,
also reported in 1940s about penicillin inducing microbes to produce
L-forms - about the time penicillin was released for mass marketing.
That some antimicrobial substances and conditions can induce microbes
to produce L-forms with potential to evolve to original and/or
atypical forms is largely ignored in our medical research community.
Emmy Kleineberger Nobel's work on L-forms is courtesy the Haffkine
Institute Library, Bombay, India. She worked 1930s-40s at the Lister
Institute, London, that is now closed.
Bartonella
===========
(a) L-forms
------------
As bartonella are pleomorphic Gram negative proteobacteria, alpha 2
subgroup of the purple bacteria, routine Gram staining can obscure
their detection. They grow best at 26-28 degrees centigrade, easily
seen in a first drop of blood from a fingertip puncture, may not be
seen in warmer venous blood except in crisis. The inclusion of
antimicrobial substances in growth media can induce microbes to
produce L-forms and atypical mycoplasma growth seen as "contaminants"
rather than as substance and or condition (heat) induced atypical
forms.
(b) Manifestations dependent on vector
--------------------------------------
Bartonellosis is considered under-reported in the "first" world. An
article by Dirk Elston, then Asst. Chairman and Chief of
Dermatopathology, Brooke Army Medical Center, USA, reports:
"Bartonellosis spread by a louse will have a different manifestation
from bartonellosis spread by a flea or a biting fly. This may, in
part, explain the varying syndromes caused by closely related
species of Bartonella organisms e.g.
(*) acute Oroya Fever,
(*) Peruvian bacillary angiomatosis,
(*) bacillary angiomatosis of AIDS,
(*) bacillary peliosis hepatitis,
(*) cat scratch disease,
(*) infectious endocarditis. The environment of the transmitting
vector can cause change in the organism - a specific species
associated with a specific disease.
D Weinman has called Bartonella bacilliformis infection a
microbiologist's curiosity, peculiar only to Peru? It seems more
reasonable to consider that the environment provided by differing
hosts (human and insect) has caused changes in the organism and that
laboratory practices obscure identification.
(c) Spread
-----------
(*) Brescia University, Italy, has reported on a case of Bartonella
bacilliformis disease in a woman returned from a visit to Peru.
(*) Some of Pizzaro's men that survived invading Peru returned to
Europe - possible carriers; and,
(*) NASA reports on dust clouds carrying infection from continent to
continent and
(*) El Nino linked to outbreaks of bartonellosis - rivers from the
Andes empty into the ocean!
(d) Our work
------------
For our studies, we draw specimen over a 10 mm glass coverslip
cellotape held at edge on a plain glass slide, methanol fix, do not
stain, for color light-micrograph and scanning electron- comparison
of same specimen.
Our work on Bartonella bacilliformis-like infection in India started
in 1987 at the Poona District Indian Red Cross Blood Bank.
Three articles on Bartonella/L-forms/mycoplasma and cardiovascular
disease, immunodeficiency and microbes and sequestered substances as
mechanisms for disease are published in Medical Hypothoses.
<http://www.ncbi.nlm.nih.gov/entrez/...b=PubMed&orig_d
b=PubMed&dispmax=100&doptcmdl=DocSum&term=Kleineberger+bartonella+Medical
hypotheses>
We completed a pilot study on infection and cataract last year -
presented at two eye conferences, article being updated to include
additional clinical data - then submitted for publishing."
|