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Home > Archive > Dentistry > September 2006 > Uptake of Hg in *MERCURY* Amalgams-Improvements of removal
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Uptake of Hg in *MERCURY* Amalgams-Improvements of removal
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| Jan Drew 2006-09-29, 4:24 pm |
| http://tinyurl.com/eu2nb
Resolution of orofacial granulomatosis with amalgam removal.
Guttman-Yassky E, Weltfriend S, Bergman R.
Department of Dermatology, Rambam Medical Centre and the Bruce Rappaport
Faculty of Medicine, Haifa, Israel. dermatology@rambam.health.gov.il
A 61-year-old woman presented with a 2-year history of an abnormal
erythematous swelling on the upper lip and cheek. Upon examination there
were no other physical findings. Histological examination found discreet
sarcoidal granulomas in the lower dermis. Routine laboratory studies, chest
radiographs and pulmonary functions were all normal. Clinical presentation
and histological findings were, therefore, compatible with the diagnosis of
orofacial granulomatosis (OFG). The patient was patch tested with an
extended standard series that included metal-salt, dental prosthesis, bakery
and corticosteroids series. The patch test was positive (score ++) after 48
and 72 h for mercury in the metal-salt and dental prosthesis series. During
the past decade the patient had received amalgam fillings of several dental
cavities, including one adjacent to the swollen cheek. The unilateral
localization of the soft tissue swelling adjacent to the amalgam tooth
fillings, along with the positive patch test for mercury, raised the
possibility that the OFG was part of a delayed hypersensitive reaction to
the fillings. The patient therefore underwent a total amalgam replacement
procedure; complete disappearance of the swelling overlying the right cheek
was observed within 7 weeks and the swelling of the upper lip subsided
completely within 6 months. We propose that mercury in amalgam tooth
fillings is another cause of OFG and suggest appropriate patch testing in
patients who do not have an apparent cause of OFG.
Publication Types:
Case Reports
PMID: 12702083 [PubMed - indexed for MEDLINE]
http://tinyurl.com/jxnjj
Oral lichenoid lesions (OLL) and mercury in amalgam fillings.
Wong L, Freeman S.
Skin and Cancer Foundation, Darlinghurst NSW, Australia.
84 patients with oral lichenoid lesions (OLL) were seen in the contact
dermatitis clinic. All these patients had reticulate, lacy, plaque-like or
erosive lichenoid changes adjacent to amalgam fillings. Patch testing to
metallic mercury, 0.1% thimerosal, 1% ammoniated mercury, 0.1% mercuric
chloride, and in some cases 0.05% phenylmercuric nitrate and amalgam discs
was undertaken. 33 (39%) patients had positive patch test findings. 30/33
patch test positive patients had replacement of their amalgam fillings, with
28 (87%) patients experiencing improvement of symptoms and signs within 3
months. This confirms that mercury allergy is a factor in the pathogenesis
of OLL in some cases. In cases where patch test negative patients improve
with amalgam replacement, mercury may be acting as an irritant in the
pathogenesis of OLL.
PMID: 12694209 [PubMed - indexed for MEDLINE]
http://tinyurl.com/lhmpr
Mercury uptake and kinetics after ingestion of dental amalgam.
af Geijersstam E, Sandborgh-Englund G, Jonsson F, Ekstrand J.
Dept. of Basic Oral Sciences, School of Dentistry, Karolinska Institutet,
Huddinge, Sweden.
The aim of the present study was to investigate the G-1 uptake of mercury
(Hg) after intake of a single dose of amalgam-Hg, followed by
pharmacokinetic analysis of the data. Eleven volunteers without amalgam
fillings ingested 1.00 g amalgam powder. Hg in plasma vs. time was analyzed
with a two-compartment model by means of mixed-effects modeling. A fraction
of the absorption rate of Hg to the central compartment was inversely
proportional to the plasma ferritin levels. The population mean half-life of
the terminal phase of Hg in plasma was 37 days, with a considerable standard
deviation in the population. The absorbed fraction of the administered dose
was estimated to be about 0.04%. It is concluded that the G-1 uptake of Hg
is of quantitative importance during dental treatment.
PMID: 11926235 [PubMed - indexed for MEDLINE]
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"Jan Drew" <jdrew1374@sbcglobal.net> wrote in message
news:5rdTg.212$NE6.43@newssvr11.news.prodigy.com...
> http://tinyurl.com/eu2nb
>
> Resolution of orofacial granulomatosis with amalgam removal.
>
> Guttman-Yassky E, Weltfriend S, Bergman R.
>
> Department of Dermatology, Rambam Medical Centre and the Bruce Rappaport
> Faculty of Medicine, Haifa, Israel. dermatology@rambam.health.gov.il
>
> A 61-year-old woman presented with a 2-year history of an abnormal
> erythematous swelling on the upper lip and cheek. Upon examination there
> were no other physical findings. Histological examination found discreet
> sarcoidal granulomas in the lower dermis. Routine laboratory studies,
> chest radiographs and pulmonary functions were all normal. Clinical
> presentation and histological findings were, therefore, compatible with
> the diagnosis of orofacial granulomatosis (OFG). The patient was patch
> tested with an extended standard series that included metal-salt, dental
> prosthesis, bakery and corticosteroids series. The patch test was positive
> (score ++) after 48 and 72 h for mercury in the metal-salt and dental
> prosthesis series. During the past decade the patient had received amalgam
> fillings of several dental cavities, including one adjacent to the swollen
> cheek. The unilateral localization of the soft tissue swelling adjacent to
> the amalgam tooth fillings, along with the positive patch test for
> mercury, raised the possibility that the OFG was part of a delayed
> hypersensitive reaction to the fillings. The patient therefore underwent a
> total amalgam replacement procedure; complete disappearance of the
> swelling overlying the right cheek was observed within 7 weeks and the
> swelling of the upper lip subsided completely within 6 months. We propose
> that mercury in amalgam tooth fillings is another cause of OFG and suggest
> appropriate patch testing in patients who do not have an apparent cause of
> OFG.
so....this person was allergic to mercury?? what's your point??
should penicillin never be used because "some" are allergic?? LOL..
also you missed the term "we propose" in the last sentence....ie...they are
guessing
>
> Publication Types:
> Case Reports
>
> PMID: 12702083 [PubMed - indexed for MEDLINE]
>
> http://tinyurl.com/jxnjj
>
> Oral lichenoid lesions (OLL) and mercury in amalgam fillings.
>
> Wong L, Freeman S.
>
> Skin and Cancer Foundation, Darlinghurst NSW, Australia.
>
> 84 patients with oral lichenoid lesions (OLL) were seen in the contact
> dermatitis clinic. All these patients had reticulate, lacy, plaque-like or
> erosive lichenoid changes adjacent to amalgam fillings. Patch testing to
> metallic mercury, 0.1% thimerosal, 1% ammoniated mercury, 0.1% mercuric
> chloride, and in some cases 0.05% phenylmercuric nitrate and amalgam discs
> was undertaken. 33 (39%) patients had positive patch test findings. 30/33
> patch test positive patients had replacement of their amalgam fillings,
> with 28 (87%) patients experiencing improvement of symptoms and signs
> within 3 months. This confirms that mercury allergy is a factor in the
> pathogenesis of OLL in some cases. In cases where patch test negative
> patients improve with amalgam replacement, mercury may be acting as an
> irritant in the pathogenesis of OLL.
>
> PMID: 12694209 [PubMed - indexed for MEDLINE]
>
> http://tinyurl.com/lhmpr
>
> Mercury uptake and kinetics after ingestion of dental amalgam.
>
> af Geijersstam E, Sandborgh-Englund G, Jonsson F, Ekstrand J.
>
> Dept. of Basic Oral Sciences, School of Dentistry, Karolinska Institutet,
> Huddinge, Sweden.
>
> The aim of the present study was to investigate the G-1 uptake of mercury
> (Hg) after intake of a single dose of amalgam-Hg, followed by
> pharmacokinetic analysis of the data. Eleven volunteers without amalgam
> fillings ingested 1.00 g amalgam powder. Hg in plasma vs. time was
> analyzed with a two-compartment model by means of mixed-effects modeling.
> A fraction of the absorption rate of Hg to the central compartment was
> inversely proportional to the plasma ferritin levels. The population mean
> half-life of the terminal phase of Hg in plasma was 37 days, with a
> considerable standard deviation in the population. The absorbed fraction
> of the administered dose was estimated to be about 0.04%. It is concluded
> that the G-1 uptake of Hg is of quantitative importance during dental
> treatment.
>
> PMID: 11926235 [PubMed - indexed for MEDLINE]
>
| |
|
|
"Jan Drew" <jdrew1374@sbcglobal.net> wrote in message
news:5rdTg.212$NE6.43@newssvr11.news.prodigy.com...
> http://tinyurl.com/eu2nb
>
> Resolution of orofacial granulomatosis with amalgam removal.
>
> Guttman-Yassky E, Weltfriend S, Bergman R.
>
> Department of Dermatology, Rambam Medical Centre and the Bruce Rappaport
> Faculty of Medicine, Haifa, Israel. dermatology@rambam.health.gov.il
>
> A 61-year-old woman presented with a 2-year history of an abnormal
> erythematous swelling on the upper lip and cheek. Upon examination there
> were no other physical findings. Histological examination found discreet
> sarcoidal granulomas in the lower dermis. Routine laboratory studies,
> chest radiographs and pulmonary functions were all normal. Clinical
> presentation and histological findings were, therefore, compatible with
> the diagnosis of orofacial granulomatosis (OFG). The patient was patch
> tested with an extended standard series that included metal-salt, dental
> prosthesis, bakery and corticosteroids series. The patch test was positive
> (score ++) after 48 and 72 h for mercury in the metal-salt and dental
> prosthesis series. During the past decade the patient had received amalgam
> fillings of several dental cavities, including one adjacent to the swollen
> cheek. The unilateral localization of the soft tissue swelling adjacent to
> the amalgam tooth fillings, along with the positive patch test for
> mercury, raised the possibility that the OFG was part of a delayed
> hypersensitive reaction to the fillings. The patient therefore underwent a
> total amalgam replacement procedure; complete disappearance of the
> swelling overlying the right cheek was observed within 7 weeks and the
> swelling of the upper lip subsided completely within 6 months. We propose
> that mercury in amalgam tooth fillings is another cause of OFG and suggest
> appropriate patch testing in patients who do not have an apparent cause of
> OFG.
>
> Publication Types:
> Case Reports
>
> PMID: 12702083 [PubMed - indexed for MEDLINE]
>
> http://tinyurl.com/jxnjj
>
> Oral lichenoid lesions (OLL) and mercury in amalgam fillings.
>
> Wong L, Freeman S.
>
> Skin and Cancer Foundation, Darlinghurst NSW, Australia.
>
> 84 patients with oral lichenoid lesions (OLL) were seen in the contact
> dermatitis clinic. All these patients had reticulate, lacy, plaque-like or
> erosive lichenoid changes adjacent to amalgam fillings. Patch testing to
> metallic mercury, 0.1% thimerosal, 1% ammoniated mercury, 0.1% mercuric
> chloride, and in some cases 0.05% phenylmercuric nitrate and amalgam discs
> was undertaken. 33 (39%) patients had positive patch test findings. 30/33
> patch test positive patients had replacement of their amalgam fillings,
> with 28 (87%) patients experiencing improvement of symptoms and signs
> within 3 months. This confirms that mercury allergy is a factor in the
> pathogenesis of OLL in some cases. In cases where patch test negative
> patients improve with amalgam replacement, mercury may be acting as an
> irritant in the pathogenesis of OLL.
again ....so some are allergic to mercury...why...I am allergic to
nickel....should ALL nickel alloys be removed from the market??
get real Janster....many if not all humans are likely to be allergic to
something...so...avoidance is the key....not taking said substance off the
market so the majority who are NOT allergic cannot have it either...
also...note the last sentence..."some cases" "may be acting as an
irritant"...ie...not even a true allergy anyway...
get a grip...
>
> PMID: 12694209 [PubMed - indexed for MEDLINE]
>
> http://tinyurl.com/lhmpr
>
> Mercury uptake and kinetics after ingestion of dental amalgam.
>
> af Geijersstam E, Sandborgh-Englund G, Jonsson F, Ekstrand J.
>
> Dept. of Basic Oral Sciences, School of Dentistry, Karolinska Institutet,
> Huddinge, Sweden.
>
> The aim of the present study was to investigate the G-1 uptake of mercury
> (Hg) after intake of a single dose of amalgam-Hg, followed by
> pharmacokinetic analysis of the data. Eleven volunteers without amalgam
> fillings ingested 1.00 g amalgam powder. Hg in plasma vs. time was
> analyzed with a two-compartment model by means of mixed-effects modeling.
> A fraction of the absorption rate of Hg to the central compartment was
> inversely proportional to the plasma ferritin levels. The population mean
> half-life of the terminal phase of Hg in plasma was 37 days, with a
> considerable standard deviation in the population. The absorbed fraction
> of the administered dose was estimated to be about 0.04%. It is concluded
> that the G-1 uptake of Hg is of quantitative importance during dental
> treatment.
>
> PMID: 11926235 [PubMed - indexed for MEDLINE]
>
| |
| Jason Johnson 2006-09-29, 9:23 pm |
| In article <kWhTg.11630$7I1.317@newssvr27.news.prodigy.net>,
<Hawki63@sbcglobal.net> wrote:
"Jan Drew" <jdrew1374@sbcglobal.net> wrote in message
news:5rdTg.212$NE6.43@newssvr11.news.prodigy.com...
> http://tinyurl.com/eu2nb
>
> Resolution of orofacial granulomatosis with amalgam removal.
>
> Guttman-Yassky E, Weltfriend S, Bergman R.
>
> Department of Dermatology, Rambam Medical Centre and the Bruce Rappaport
> Faculty of Medicine, Haifa, Israel. dermatology@rambam.health.gov.il
>
> A 61-year-old woman presented with a 2-year history of an abnormal
> erythematous swelling on the upper lip and cheek. Upon examination there
> were no other physical findings. Histological examination found discreet
> sarcoidal granulomas in the lower dermis. Routine laboratory studies,
> chest radiographs and pulmonary functions were all normal. Clinical
> presentation and histological findings were, therefore, compatible with
> the diagnosis of orofacial granulomatosis (OFG). The patient was patch
> tested with an extended standard series that included metal-salt, dental
> prosthesis, bakery and corticosteroids series. The patch test was positive
> (score ++) after 48 and 72 h for mercury in the metal-salt and dental
> prosthesis series. During the past decade the patient had received amalgam
> fillings of several dental cavities, including one adjacent to the swollen
> cheek. The unilateral localization of the soft tissue swelling adjacent to
> the amalgam tooth fillings, along with the positive patch test for
> mercury, raised the possibility that the OFG was part of a delayed
> hypersensitive reaction to the fillings. The patient therefore underwent a
> total amalgam replacement procedure; complete disappearance of the
> swelling overlying the right cheek was observed within 7 weeks and the
> swelling of the upper lip subsided completely within 6 months. We propose
> that mercury in amalgam tooth fillings is another cause of OFG and suggest
> appropriate patch testing in patients who do not have an apparent cause of
> OFG.
>
> Publication Types:
> Case Reports
>
> PMID: 12702083 [PubMed - indexed for MEDLINE]
>
> http://tinyurl.com/jxnjj
>
> Oral lichenoid lesions (OLL) and mercury in amalgam fillings.
>
> Wong L, Freeman S.
>
> Skin and Cancer Foundation, Darlinghurst NSW, Australia.
>
> 84 patients with oral lichenoid lesions (OLL) were seen in the contact
> dermatitis clinic. All these patients had reticulate, lacy, plaque-like or
> erosive lichenoid changes adjacent to amalgam fillings. Patch testing to
> metallic mercury, 0.1% thimerosal, 1% ammoniated mercury, 0.1% mercuric
> chloride, and in some cases 0.05% phenylmercuric nitrate and amalgam discs
> was undertaken. 33 (39%) patients had positive patch test findings. 30/33
> patch test positive patients had replacement of their amalgam fillings,
> with 28 (87%) patients experiencing improvement of symptoms and signs
> within 3 months. This confirms that mercury allergy is a factor in the
> pathogenesis of OLL in some cases. In cases where patch test negative
> patients improve with amalgam replacement, mercury may be acting as an
> irritant in the pathogenesis of OLL.
again ....so some are allergic to mercury...why...I am allergic to
nickel....should ALL nickel alloys be removed from the market??
get real Janster....many if not all humans are likely to be allergic to
something...so...avoidance is the key....not taking said substance off the
market so the majority who are NOT allergic cannot have it either...
also...note the last sentence..."some cases" "may be acting as an
irritant"...ie...not even a true allergy anyway...
get a grip...
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Yes, I agree that some people are allergic to mercury. What would happen
if a child that was allegic to mercury was given several vaccines that
contained mercury? That is one of the reasons that children and adults
should NOT be given vaccines that contain mercury. I believe that dentists
should be required to test people to determine if they are allergic to
mercury before making use of dental fillings that contain mercury. Another
even better sollution would be to make it illegal for dentists to use
dental fillings that contain mercury.
Jason
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
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