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Home > Archive > Arthritis > February 2007 > The joint is doomed / Blood leakage in joint
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The joint is doomed / Blood leakage in joint
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| ironjustice@aol.com 2007-02-12, 4:24 pm |
| <<snip>>
eventual osteoarthritis set in
<<snip>>
The destructive capabilities of the synovium in the haemophilic joint.
Rodriguez-Merchan EC
Haemophilia. 1998 Jul ; 4(4): 506-10
The pathogenesis of chronic haemophilic synovitis and the destructive
capabilities of the synovium are multifactorial. As a result of
repeated haemarthroses, synovial hyperthrophy occurs, iron and
cellular debris are phagocytized, and hydrolytic enzymes synthesized
by the proliferating synovium are released into the joint. An
inflammatory process develops, and the nutrition of the articular
cartilage is affected by the abnormal synovial fluid, immobilization
of the joint, and the presence of fibrous adhesions. Chronic
hypertrophic synovitis is a progressive destructive condition in the
joint and, unless it is treated, the joint is doomed. With the
development of cartilaginous destruction, progressive chondrolysis and
eventual osteoarthritis set in.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
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| Fire Chief 2007-02-12, 4:24 pm |
| On Feb 11, 10:43 am, numbnutz tom wrote from an 8-year-old study:
> Haemophilia. 1998 Jul ; 4(4): 506-10
> Man Is A Herbivore!http://tinyurl.com/a3cc3
Created with incisor and canine teeth to rip apart, chew and eat
MEAT
.... P.E.T.A -- People Eating Tasty Animals
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| ironjustice 2007-02-12, 4:24 pm |
| [vbcol=seagreen]
On Feb 11, 10:43 am, numbnutz tom wrote from an 8-year-old study:
Haemophilia. 1998 Jul ; 4(4): 506-10<<
What you think it wasn't caused by .. and is STILL caused by .. blood
spillage into the joint .. ?
You have any better ideas .. ?
Seems it is a .. model of .. osteoarthritis and rheumatoid
arthritis .. and since .. BOTH .. resemble the destruction caused by
spillage of blood into the joint .. then .. since blood DOES SPILL
INTO THE JOINT .. upon general wear and walking and moving .. then ..
blood can and DOES .. come into the .. scenario ..
Big .. guy ..
And .. therefore .. the iron binding drugs .. **used** EXTENSIVELY
like sulfasalazine .. indocin .. aspirin .. bucillamine .. etc ,
etc .. make .. sense ..
To anyone with half a .. brain ..
<<snip>>
haemophilia-resembling diseases (Rheumatoid Arthritis and
Osteoarthritis)
<<snip>>
Haemophilia. 2005 Jul;11(4):308-18. Links
Assessing functional health status in adults with haemophilia: towards
a preliminary core set of clinimetric instruments based on a
literature search in Rheumatoid Arthritis and Osteoarthritis.
de Kleijn P, van Genderen FR, van Meeteren NL.
Van Creveldkliniek, university Medical Centre Utrecht, Utrecht, The
Netherlands. P.dekleijn@azu.nl
People with haemophilia experience a progressive deterioration of
their functional health status. Regular clinical assessment of
functional health status provides insight into their process of
disablement. As such, the development of a core-set of measurement
tools is warranted. The aim of this study was to gather data to
prepare a (preliminary) core set of clinically relevant and feasible
instruments to assess the functional health status of adults with
haemophilia, and to indicate their psychometric qualities. Therefore,
clinimetric instruments frequently used in two haemophilia-resembling
diseases (Rheumatoid Arthritis and Osteoarthritis) were reviewed from
the literature. An extensive search in Medline yielded 13 relevant
review articles, incorporating a total of 182 instruments, of which 40
were appropriate for haemophilia. Of these 40 instruments 3 measure
body structures, 13 body functions, 19 activities (of which 5 are
performance based and 14 self-report based), and 3 measure
participation. This classification is based on the International
Classification of Functioning, Disability and Health. Detailed
information regarding the psychometrics (reliability, validity and
responsiveness) of four instruments is described fully in the
literature, whereas the psychometrics of the majority of the other
instruments are only partly described. The results of this literature
study may contribute to the formation of a (preliminary) core set of
clinimetric instruments to assess the functional health status of
adults with haemophilia. Decisions on the final core set should be
held within the Musculoskeletal Committee of the World Federation of
Haemophilia.
PMID: 16011581 [PubMed - indexed for MEDLINE]
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
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