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Home > Archive > Arthritis > August 2005 > Mother of young sufferer
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Mother of young sufferer
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| suzidingle@aol.com 2005-04-27, 5:46 pm |
| I am the Mother of "Green" who posted under the topic young sufferer.
I want to be able to support her and try to understand the nature of
this beast. I am a nurse and know somewhat of the process, yet when it
touches someone you love an illness such as this really can knock the
wind out of you.
Does anyone have any suggestions for reading? I just shipped my
daughter a book called Rheumatoid Arthritis: The Infection Connection.
I'd appreciate any feedback as to what I can purchase to educate myself
in this area.
Does RA tend to be cyclitic in nature? Could I have passed this on to
her? I have been very ill with a clinical diagnosed case of Lyme
Disease. Her brother has a high lyme count as well. I am concerned
with how far this will go degeneratively. My daughter is a beautiful
person both inside and out. She has been dealing with this alone and I
want her to know how much she needs support. Thanks to boards like
these that allow us to share feelings and concerns. Knowing the
medical world we generally do not find compassion in those who are
suppose to care for us. Until you read someone else who is enduring
the same as you do only then do you feel less alone. So thanks for all
your input. And thanks for supporting my daughter in answering her
postings. God bless all.
Any news in stem cell work? Or has the Bush team taken that off the
table?
| |
| ironjustice@aol.com 2005-05-02, 8:45 am |
| If you look below .. iron .. seems to be a problem .. and if iron
supplements are a problem .. then .. logic .. tells you .. iron filings
added to every bit of floured product your child .. eats .. WILL ..
cause .. destruction ..
EXPERIMENTAL BIOLOGY UPDATE: Arthritic kids' iron supplements may
hasten joint deterioration
By Diana Swift
WWASHINGTON, D.C. - The iron supplements that many arthritic children
take to combat concomitant anemia may be hastening the deterioration of
their joints, Houston researchers say.
Led by biologist Roman Shypailo of the Children's Nutrition Research
Centre at Baylor college of Medicine, a Texas team looked at eight
children being treated for juvenile rheumatoid arthritis. The patients,
aged five to 15 years, received an intravenous radioactive tracer dose
of iron (0.03 microsievert). Iron activity in affected joints was
monitored on a position/energy-sensitive gamma counter, while a second
machine monitored whole-body iron retention. Iron deposition was
measured two hours post-infusion and again at days seven, 14, 28 and
56.
Anemic
"We found that iron excessively accumulates in arthritic joints and
probably contributes to the chronic damage," said Shypailo. "That puts
you between a rock and a hard place because many of these arthritic
kids are anemic and need iron supplements, which may worsen the
disease."
The study found a high level of agreement between the joint data and
the whole-body data, with a greater than 90% retention rate of the
infused iron both in joints and systemically. Furthermore, six of eight
patients showed increased uptake at the affected joints: 165% over the
first 30 days compared with initial uptake at two hours.
The next step, he says, is to see if there is excessive deposition of
dietary iron in arthritic joints.
Ann Rheum Dis 1989 May;48(5):382-8
Investigation of the anti-inflammatory properties of
hydroxypyridinones.
Hewitt SD, Hider RC, Sarpong P, Morris CJ, Blake DR
Cancer Research Unit, university of York, Heslington.
Synovial iron deposition associated with rheumatoid disease may
result
in the production of highly reactive oxygen free radicals, leading
to
tissue damage. This chain of events can be interrupted by iron
chelation. Families of strong iron (III) chelators have been tested
for their iron scavenging properties in vitro and their effects
assessed in vivo using a rat model of inflammation. All the
chelators
competed successfully for iron with apotransferrin, and some removed
up to 34% of iron from ferritin. The best anti-inflammatory effects
were achieved with the most hydrophilic chelators and those which
chelated iron most avidly. Activity was dependent on dose. The route
of administration was also an important factor with lower affinity
chelators. This work introduces a range of simple bidentate iron
chelators, which under certain conditions exceed desferrioxamine in
their iron scavenging abilities, and some of which, in this simple
animal model, approach indomethacin in their anti-inflammatory
capabilities.
Comments:
* Comment in: Ann Rheum Dis 1990 Nov;49(11):956-7
PMID: 2730166, UI: 89272259
______________________________=AD
Who loves ya.
Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking
| |
| greenknees 2005-05-03, 8:46 am |
| blank faced. <blink blink>
greenknees
| |
| ironjustice@aol.com 2005-05-04, 8:46 am |
| If you look below .. iron .. seems to be a problem .. and if iron
supplements are a problem .. then .. logic .. tells you .. iron filings
added to every bit of floured product your child .. eats .. WILL ..
cause .. destruction ..
EXPERIMENTAL BIOLOGY UPDATE: Arthritic kids' iron supplements may
hasten joint deterioration
By Diana Swift
WWASHINGTON, D.C. - The iron supplements that many arthritic children
take to combat concomitant anemia may be hastening the deterioration of
their joints, Houston researchers say.
Led by biologist Roman Shypailo of the Children's Nutrition Research
Centre at Baylor college of Medicine, a Texas team looked at eight
children being treated for juvenile rheumatoid arthritis. The patients,
aged five to 15 years, received an intravenous radioactive tracer dose
of iron (0.03 microsievert). Iron activity in affected joints was
monitored on a position/energy-sensitive gamma counter, while a second
machine monitored whole-body iron retention. Iron deposition was
measured two hours post-infusion and again at days seven, 14, 28 and
56.
Anemic
"We found that iron excessively accumulates in arthritic joints and
probably contributes to the chronic damage," said Shypailo. "That puts
you between a rock and a hard place because many of these arthritic
kids are anemic and need iron supplements, which may worsen the
disease."
The study found a high level of agreement between the joint data and
the whole-body data, with a greater than 90% retention rate of the
infused iron both in joints and systemically. Furthermore, six of eight
patients showed increased uptake at the affected joints: 165% over the
first 30 days compared with initial uptake at two hours.
The next step, he says, is to see if there is excessive deposition of
dietary iron in arthritic joints.
Ann Rheum Dis 1989 May;48(5):382-8
Investigation of the anti-inflammatory properties of
hydroxypyridinones.
Hewitt SD, Hider RC, Sarpong P, Morris CJ, Blake DR
Cancer Research Unit, university of York, Heslington.
Synovial iron deposition associated with rheumatoid disease may
result
in the production of highly reactive oxygen free radicals, leading
to
tissue damage. This chain of events can be interrupted by iron
chelation. Families of strong iron (III) chelators have been tested
for their iron scavenging properties in vitro and their effects
assessed in vivo using a rat model of inflammation. All the
chelators
competed successfully for iron with apotransferrin, and some removed
up to 34% of iron from ferritin. The best anti-inflammatory effects
were achieved with the most hydrophilic chelators and those which
chelated iron most avidly. Activity was dependent on dose. The route
of administration was also an important factor with lower affinity
chelators. This work introduces a range of simple bidentate iron
chelators, which under certain conditions exceed desferrioxamine in
their iron scavenging abilities, and some of which, in this simple
animal model, approach indomethacin in their anti-inflammatory
capabilities.
Comments:
* Comment in: Ann Rheum Dis 1990 Nov;49(11):956-7
PMID: 2730166, UI: 89272259
______________________________=AD
Who loves ya.
Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking
| |
| greenknees 2005-05-06, 11:46 am |
| blank faced. <blink blink>
greenknees
| |
| LRitchhart 2005-08-01, 5:47 pm |
| please do some research on "glyconutrients" and RA on the internet. Also
www.glycoscience.org
Hope this is helpful.
<suzidingle@aol.com> wrote in message
news:1114123144.447087.37130@z14g2000cwz.googlegroups.com...
>I am the Mother of "Green" who posted under the topic young sufferer.
> I want to be able to support her and try to understand the nature of
> this beast. I am a nurse and know somewhat of the process, yet when it
> touches someone you love an illness such as this really can knock the
> wind out of you.
> Does anyone have any suggestions for reading? I just shipped my
> daughter a book called Rheumatoid Arthritis: The Infection Connection.
> I'd appreciate any feedback as to what I can purchase to educate myself
> in this area.
>
> Does RA tend to be cyclitic in nature? Could I have passed this on to
> her? I have been very ill with a clinical diagnosed case of Lyme
> Disease. Her brother has a high lyme count as well. I am concerned
> with how far this will go degeneratively. My daughter is a beautiful
> person both inside and out. She has been dealing with this alone and I
> want her to know how much she needs support. Thanks to boards like
> these that allow us to share feelings and concerns. Knowing the
> medical world we generally do not find compassion in those who are
> suppose to care for us. Until you read someone else who is enduring
> the same as you do only then do you feel less alone. So thanks for all
> your input. And thanks for supporting my daughter in answering her
> postings. God bless all.
>
> Any news in stem cell work? Or has the Bush team taken that off the
> table?
>
| |
| Harvey R. Stone 2005-08-01, 5:47 pm |
|
"LRitchhart" <LRitchhart@cox.net> wrote in message
news:3MsHe.855$_t.692@okepread01...
> please do some research on "glyconutrients" and RA on the internet. Also
> www
>
> Hope this is helpful.
>
> <som> wrote in message
Aaah a mannatech site. This is advertising for a line of products seen
here many times. Nothing new about this and if seen again,,,, it will be
reported to all ISPs involved.
Harv
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