Arthritis - Long-term use of Advil, Aleve could lead to heart problems

Author

Long-term use of Advil, Aleve could lead to heart problems

Roman Bystrianyk

2005-04-20, 8:46 am

http://www.healthsentinel.com/news....ist_item&id=748

Marilynn Marchione, "Long-term use of Advil, Aleve could lead to heart
problems", Chicago-Sun Times, April 19, 2005,
Link: http://www.suntimes.com/output/heal...-nws-ibu19.html

With prescription drugs Vioxx and Bextra already pulled from the
market, a study has raised questions about the heart safety of
long-term use of over-the-counter pain relievers such as Advil, Motrin
and Aleve.

Smokers in Norway who took such drugs for at least six months had twice
the risk of dying of a heart attack, stroke or other heart-related
problem.

The findings came from a study of whether these pain relievers could
prevent oral cancer. The drugs did cut the risk of developing oral
cancer in half.

But the deaths that were prevented were offset by the increased risk of
dying from cardiovascular disease, according to the study, reported
Monday at an American Association for Cancer Research conference in
Anaheim.

The study was small -- 908 people -- and involved people prone to heart
problems and cancer. But specialists said it supports the Food and Drug
Administration's decision to warn about long-term use of all such
painkillers except aspirin.

The findings add to the suspicion that the heart risk extends beyond
the cox-2 drugs -- Bextra, Vioxx and Celebrex -- to medications known
as non-steroidal anti-inflammatory drugs, or NSAIDs, which include
naproxen, ibuprofen and other over-the-counter pain relievers except
acetaminophen.

''To the best of our knowledge, these are the first data to support
putting a box warning on NSAIDs, not just cox-2s,'' said Dr. Andrew
Dannenberg of Cornell University.

Harvey R. Stone

2005-04-20, 5:46 pm

Hi Roman,,,, I can only tell you that before my RA was confirmed,,,,, I
took prescription Naprosyn for 7 years at the max amount of 3 500 mg pills a
day and it kept me working and supporting two of my four kids in collage.
I know, I know, I have one of those stomachs that seem to be made of iron.
No ulcers, no heart problems,,,, in fact it was a life saver for me for that
period of time.....
I take these scare messages should be taken with a grain of salt with
the advice of a good doctor.
Harv
"Roman Bystrianyk" <rbystrianyk@gmail.com> wrote in message
news:1113999803.810079.110560@l41g2000cwc.googlegroups.com...
> http://www.healthsentinel.com/news....ist_item&id=748
>
> Marilynn Marchione, "Long-term use of Advil, Aleve could lead to heart
> problems", Chicago-Sun Times, April 19, 2005,
> Link: http://www.suntimes.com/output/heal...-nws-ibu19.html
>
> With prescription drugs Vioxx and Bextra already pulled from the
> market, a study has raised questions about the heart safety of
> long-term use of over-the-counter pain relievers such as Advil, Motrin
> and Aleve.
>
> Smokers in Norway who took such drugs for at least six months had twice
> the risk of dying of a heart attack, stroke or other heart-related
> problem.
>
> The findings came from a study of whether these pain relievers could
> prevent oral cancer. The drugs did cut the risk of developing oral
> cancer in half.
>
> But the deaths that were prevented were offset by the increased risk of
> dying from cardiovascular disease, according to the study, reported
> Monday at an American Association for Cancer Research conference in
> Anaheim.
>
> The study was small -- 908 people -- and involved people prone to heart
> problems and cancer. But specialists said it supports the Food and Drug
> Administration's decision to warn about long-term use of all such
> painkillers except aspirin.
>
> The findings add to the suspicion that the heart risk extends beyond
> the cox-2 drugs -- Bextra, Vioxx and Celebrex -- to medications known
> as non-steroidal anti-inflammatory drugs, or NSAIDs, which include
> naproxen, ibuprofen and other over-the-counter pain relievers except
> acetaminophen.
>
> ''To the best of our knowledge, these are the first data to support
> putting a box warning on NSAIDs, not just cox-2s,'' said Dr. Andrew
> Dannenberg of Cornell University.
>

LadyLollipop

2005-04-20, 5:46 pm

"Harvey R. Stone" <none@nobody.net> wrote in message
news:1Uv9e.578$%L1.482@newssvr30.news.prodigy.com...
> Hi Roman,,,, I can only tell you that before my RA was confirmed,,,,, I
> took prescription Naprosyn for 7 years at the max amount of 3 500 mg pills
> a day and it kept me working and supporting two of my four kids in
> collage. I know, I know, I have one of those stomachs that seem to be
> made of iron. No ulcers, no heart problems,,,, in fact it was a life saver
> for me for that period of time.....
> I take these scare messages should be taken with a grain of salt
> with the advice of a good doctor.
> Harv

There ya go, a true *organized medicine* believer, who calls studies scare
messages.

Keep your fingers crossed Harv.

LL/Jan

> "Roman Bystrianyk" <rbystrianyk@gmail.com> wrote in message
> news:1113999803.810079.110560@l41g2000cwc.googlegroups.com...
>
>

Joel M. Eichen

2005-04-20, 5:46 pm

"LadyLollipop" <LadyLollipop@insightbb.com> wrote in message
news:hVw9e.4257$WI3.591@attbi_s71...
>
> "Harvey R. Stone" <none@nobody.net> wrote in message
> news:1Uv9e.578$%L1.482@newssvr30.news.prodigy.com...
I[vbcol=seagreen]
pills[vbcol=seagreen]
saver[vbcol=seagreen]

WE AGREE. Its like amalgamitis and
Break Dancing ... so far, no causal relationship.

Joel

[vbcol=seagreen]
>
> There ya go, a true *organized medicine* believer, who calls studies scare
> messages.
>
> Keep your fingers crossed Harv.
>
> LL/Jan
>
>
>
>
http://www.healthsentinel.com/news....ist_item&id=748[vbcol=seagreen]
>
>

Shyster

2005-04-21, 8:45 am

"Joel M. Eichen" <joeleichen@yahoo.com> wrote in message
news:4266d824_1@x-privat.org...
>
> "LadyLollipop" <LadyLollipop@insightbb.com> wrote in message
> news:hVw9e.4257$WI3.591@attbi_s71...
confirmed,,,,,[vbcol=seagreen]
> I
> pills

Did you ever graduate from collage to abstract?

I know, I know, I have one of those stomachs that seem to be[vbcol=seagreen]
> saver
>
> WE AGREE. Its like amalgamitis and
> Break Dancing ... so far, no causal relationship.
>
> Joel
>
>
>
>
scare[vbcol=seagreen]
> http://www.healthsentinel.com/news....ist_item&id=748
heart[vbcol=seagreen]
Motrin[vbcol=seagreen]
twice[vbcol=seagreen]
of[vbcol=seagreen]
heart[vbcol=seagreen]
Drug[vbcol=seagreen]
>
>

Shyster

2005-04-27, 5:46 pm