| Andrew B. Chung, MD/PhD 2005-01-07, 7:06 am |
| Robert Klute wrote:
>
> On Sat, 01 Jan 2005 23:25:31 GMT, nospam@pacbell.net wrote:
>
>
> Well, they do need to crunch the numbers first. I see it as a knee jerk
> reaction to recent announcements about COX-2 inhibitors.
>
> The participants in the ADAPT study were over 70 and had a family
> history senility, but were allowed to take 81mg of aspirin per day. The
> preliminary results showed a 50% increased risk of cardiovascular events
> in the naproxen group over the placebo group.
>
> On the other hand, another study showed that taking aspirin and
> ibuprofen had nearly twice the risk of death from any cause -- and a 73%
> increased risk of death from heart disease. So, depending on how many
> of the participants took aspirin daily, the results MAY just show that
> naproxen, like ibuprofen, reduces the effectiveness of aspirin.
I believed the investigators have controlled for the aspirin use.
At His service,
Andrew
--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist
**
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