| Iconoclaster 2005-09-25, 10:16 am |
| Paper #3 is about monotherapy with Peginterferon a-2b:
>"Results: Five untreated subjects had spontaneous recovery and another 4
subjects scheduled to start treatment at weeks 12 or 20 resolved
spontaneously before therapy. 79 subjects with persistent viremia were
randomized to 3 groups (Table). The end of treatment response was 94% and
the overall SVR was 82%. The SVR was better for genotype 4 compared to
genotype 1. Earlier treatment (week 8 or 12) was associated with higher
SVR particularly in genotype 1. Twelve week therapy was sufficient for
genotype 4 while higher SVR rates in genotype 1 patients were achieved
with 24 wks treatment (86%). Peginterferon c~-2b monotherapy was well
tolerated and associated with significant improvement in the quality of
life."
These genotypes depend on what kind of genetic sludge has been used to
prime the PCR.
Peginterferon a-2b is well-tolerated. As a monotherapy it will not kill
you as easily as in combination with Ribavirin. I can believe that.
But just waiting until the condition clears up by itself, as happened to 9
subjects, works too.
|